2B78.DE vs. GN0M.DE
2B78.DE (iShares Healthcare Innovation UCITS ETF) and GN0M.DE (Global X Genomics & Biotechnology UCITS ETF) are both Health & Biotech Equities funds - 2B78.DE tracks the iSTOXX® FactSet Breakthrough Healthcare while GN0M.DE tracks the Solactive Genomics. Both are passively managed. Over the past 3 years, 2B78.DE returned 2.27%/yr vs -1.90%/yr for GN0M.DE. Their correlation of 0.86 suggests significant overlap in exposure. 2B78.DE charges 0.40%/yr vs 0.50%/yr for GN0M.DE.
Performance
2B78.DE vs. GN0M.DE - Performance Comparison
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Returns By Period
In the year-to-date period, 2B78.DE achieves a -2.07% return, which is significantly lower than GN0M.DE's 12.99% return.
2B78.DE
- 1D
- 0.41%
- 1M
- 1.41%
- YTD
- -2.07%
- 6M
- -3.15%
- 1Y
- 14.42%
- 3Y*
- 2.27%
- 5Y*
- -1.74%
- 10Y*
- —
GN0M.DE
- 1D
- 5.61%
- 1M
- 11.50%
- YTD
- 12.99%
- 6M
- 9.82%
- 1Y
- 55.73%
- 3Y*
- -1.90%
- 5Y*
- —
- 10Y*
- —
2B78.DE vs. GN0M.DE - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | |
|---|---|---|---|---|---|---|
2B78.DE iShares Healthcare Innovation UCITS ETF | -2.07% | 5.50% | 7.24% | -0.29% | -19.03% | -2.64% |
GN0M.DE Global X Genomics & Biotechnology UCITS ETF | 12.99% | 5.67% | -12.40% | -9.04% | -32.50% | -7.90% |
Correlation
The correlation between 2B78.DE and GN0M.DE is 0.83, indicating a strong positive relationship between their price movements. Combining them offers limited diversification - they tend to fall together during downturns.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.83 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.84 |
Correlation (All Time) Calculated using the full available price history since Nov 12, 2021 | 0.86 |
The correlation between 2B78.DE and GN0M.DE has been stable across timeframes, ranging from 0.83 to 0.86 - a consistent structural relationship.
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Return for Risk
2B78.DE vs. GN0M.DE — Risk / Return Rank
2B78.DE
GN0M.DE
2B78.DE vs. GN0M.DE - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for iShares Healthcare Innovation UCITS ETF (2B78.DE) and Global X Genomics & Biotechnology UCITS ETF (GN0M.DE). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| 2B78.DE | GN0M.DE | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -1.05 | ||
| Sortino ratioReturn per unit of downside risk | -1.38 | ||
| Omega ratioGain probability vs. loss probability | 1.17 | 1.33 | -0.16 |
| Calmar ratioReturn relative to maximum drawdown | 1.24 | 3.32 | -2.09 |
| Martin ratioReturn relative to average drawdown | 3.07 | 8.35 | -5.28 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| 2B78.DE | GN0M.DE | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 0.95 | 2.00 | -1.05 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | -0.10 | — | — |
Sharpe Ratio (All Time)Calculated using the full available price history | 0.31 | -0.34 | +0.65 |
Drawdowns
2B78.DE vs. GN0M.DE - Drawdown Comparison
The maximum 2B78.DE drawdown since its inception was -38.58%, smaller than the maximum GN0M.DE drawdown of -67.19%. Use the drawdown chart below to compare losses from any high point for 2B78.DE and GN0M.DE.
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Drawdown Indicators
| 2B78.DE | GN0M.DE | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -38.58% | -67.19% | +28.61% |
Max Drawdown (1Y)Largest decline over 1 year | -12.05% | -16.68% | +4.63% |
Max Drawdown (3Y)Largest decline over 3 years | -25.32% | -48.19% | +22.87% |
Max Drawdown (5Y)Largest decline over 5 years | -36.99% | — | — |
Current DrawdownCurrent decline from peak | -19.03% | -41.03% | +22.00% |
Average DrawdownAverage peak-to-trough decline | -14.36% | -43.13% | +28.77% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 4.86% | 6.65% | -1.79% |
Volatility
2B78.DE vs. GN0M.DE - Volatility Comparison
The current volatility for iShares Healthcare Innovation UCITS ETF (2B78.DE) is 3.74%, while Global X Genomics & Biotechnology UCITS ETF (GN0M.DE) has a volatility of 8.15%. This indicates that 2B78.DE experiences smaller price fluctuations and is considered to be less risky than GN0M.DE based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| 2B78.DE | GN0M.DE | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 3.74% | 8.15% | -4.41% |
Volatility (6M)Calculated over the trailing 6-month period | 10.97% | 19.69% | -8.72% |
Volatility (1Y)Calculated over the trailing 1-year period | 15.67% | 27.68% | -12.01% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 17.91% | 31.49% | -13.58% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 18.79% | 31.49% | -12.70% |
2B78.DE vs. GN0M.DE - Expense Ratio Comparison
2B78.DE has a 0.40% expense ratio, which is lower than GN0M.DE's 0.50% expense ratio.
Dividends
2B78.DE vs. GN0M.DE - Dividend Comparison
Neither 2B78.DE nor GN0M.DE has paid dividends to shareholders.
Frequently Asked Questions
2B78.DE and GN0M.DE have a correlation of 0.83, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
On fees, 2B78.DE is cheaper at 0.40% per year. The better choice depends on whether you care most about return, fees, risk, or income.
2B78.DE is cheaper with a 0.40% expense ratio, compared with 0.50% for GN0M.DE.
2B78.DE tracks iSTOXX® FactSet Breakthrough Healthcare, while GN0M.DE tracks Solactive Genomics. They also come from different issuers: iShares and Global X. Their fees differ too: 0.40% for 2B78.DE and 0.50% for GN0M.DE.
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