2B78.DE vs. ESIH.DE
2B78.DE (iShares Healthcare Innovation UCITS ETF) and ESIH.DE (iShares MSCI Europe Health Care Sector UCITS ETF EUR (Acc)) are both Health & Biotech Equities funds from iShares - 2B78.DE tracks the iSTOXX® FactSet Breakthrough Healthcare while ESIH.DE tracks the MSCI World/Health Care NR USD. Both are passively managed. Over the past 5 years, 2B78.DE returned -1.74%/yr vs 5.74%/yr for ESIH.DE. A 0.56 correlation means they provide meaningful diversification when combined. 2B78.DE charges 0.40%/yr vs 0.18%/yr for ESIH.DE.
Performance
2B78.DE vs. ESIH.DE - Performance Comparison
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Returns By Period
In the year-to-date period, 2B78.DE achieves a -2.07% return, which is significantly higher than ESIH.DE's -2.35% return.
2B78.DE
- 1D
- 0.41%
- 1M
- 1.41%
- YTD
- -2.07%
- 6M
- -3.15%
- 1Y
- 14.42%
- 3Y*
- 2.27%
- 5Y*
- -1.74%
- 10Y*
- —
ESIH.DE
- 1D
- 3.10%
- 1M
- 0.16%
- YTD
- -2.35%
- 6M
- -1.01%
- 1Y
- 6.11%
- 3Y*
- 2.72%
- 5Y*
- 5.74%
- 10Y*
- —
2B78.DE vs. ESIH.DE - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | |
|---|---|---|---|---|---|---|---|
2B78.DE iShares Healthcare Innovation UCITS ETF | -2.07% | 5.50% | 7.24% | -0.29% | -19.03% | 1.15% | 7.59% |
ESIH.DE iShares MSCI Europe Health Care Sector UCITS ETF EUR (Acc) | -2.35% | 7.95% | 4.09% | 7.63% | -4.59% | 25.93% | -0.69% |
Correlation
The correlation between 2B78.DE and ESIH.DE is 0.64, which is moderate. They share some common price drivers but move independently often enough to provide real diversification benefit when combined.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.64 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.56 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.56 |
Correlation (All Time) Calculated using the full available price history since Nov 23, 2020 | 0.56 |
The correlation between 2B78.DE and ESIH.DE has been stable across timeframes, ranging from 0.56 to 0.64 - a consistent structural relationship.
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Return for Risk
2B78.DE vs. ESIH.DE — Risk / Return Rank
2B78.DE
ESIH.DE
2B78.DE vs. ESIH.DE - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for iShares Healthcare Innovation UCITS ETF (2B78.DE) and iShares MSCI Europe Health Care Sector UCITS ETF EUR (Acc) (ESIH.DE). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| 2B78.DE | ESIH.DE | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +0.60 | ||
| Sortino ratioReturn per unit of downside risk | +0.81 | ||
| Omega ratioGain probability vs. loss probability | 1.17 | 1.07 | +0.09 |
| Calmar ratioReturn relative to maximum drawdown | 1.24 | 0.47 | +0.77 |
| Martin ratioReturn relative to average drawdown | 3.07 | 1.05 | +2.02 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| 2B78.DE | ESIH.DE | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 0.95 | 0.35 | +0.60 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | -0.10 | 0.36 | -0.45 |
Sharpe Ratio (All Time)Calculated using the full available price history | 0.31 | 0.41 | -0.10 |
Drawdowns
2B78.DE vs. ESIH.DE - Drawdown Comparison
The maximum 2B78.DE drawdown since its inception was -38.58%, which is greater than ESIH.DE's maximum drawdown of -26.69%. Use the drawdown chart below to compare losses from any high point for 2B78.DE and ESIH.DE.
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Drawdown Indicators
| 2B78.DE | ESIH.DE | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -38.58% | -26.69% | -11.89% |
Max Drawdown (1Y)Largest decline over 1 year | -12.05% | -12.82% | +0.77% |
Max Drawdown (3Y)Largest decline over 3 years | -25.32% | -26.69% | +1.37% |
Max Drawdown (5Y)Largest decline over 5 years | -36.99% | -26.69% | -10.30% |
Current DrawdownCurrent decline from peak | -19.03% | -10.96% | -8.07% |
Average DrawdownAverage peak-to-trough decline | -14.36% | -7.24% | -7.12% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 4.86% | 5.75% | -0.89% |
Volatility
2B78.DE vs. ESIH.DE - Volatility Comparison
The current volatility for iShares Healthcare Innovation UCITS ETF (2B78.DE) is 3.74%, while iShares MSCI Europe Health Care Sector UCITS ETF EUR (Acc) (ESIH.DE) has a volatility of 5.87%. This indicates that 2B78.DE experiences smaller price fluctuations and is considered to be less risky than ESIH.DE based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| 2B78.DE | ESIH.DE | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 3.74% | 5.87% | -2.13% |
Volatility (6M)Calculated over the trailing 6-month period | 10.97% | 11.96% | -0.99% |
Volatility (1Y)Calculated over the trailing 1-year period | 15.67% | 17.18% | -1.51% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 17.91% | 15.86% | +2.05% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 18.79% | 15.61% | +3.18% |
2B78.DE vs. ESIH.DE - Expense Ratio Comparison
2B78.DE has a 0.40% expense ratio, which is higher than ESIH.DE's 0.18% expense ratio.
Dividends
2B78.DE vs. ESIH.DE - Dividend Comparison
Neither 2B78.DE nor ESIH.DE has paid dividends to shareholders.
Frequently Asked Questions
2B78.DE and ESIH.DE have a correlation of 0.64, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
On fees, ESIH.DE is cheaper at 0.18% per year. The better choice depends on whether you care most about return, fees, risk, or income.
ESIH.DE is cheaper with a 0.18% expense ratio, compared with 0.40% for 2B78.DE.
2B78.DE tracks iSTOXX® FactSet Breakthrough Healthcare, while ESIH.DE tracks MSCI World/Health Care NR USD. Their fees differ too: 0.40% for 2B78.DE and 0.18% for ESIH.DE.
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