2359.HK vs. NTRA

Last updated Jun 13, 2026

2359.HK (WuXi AppTec Co Ltd H) and NTRA (Natera, Inc.) are both stocks. Both operate in the Diagnostics & Research industry within the Healthcare sector. Over the past 5 years, 2359.HK returned -4.01%/yr vs 15.56%/yr for NTRA. At a 0.05 correlation, their price movements are largely independent.

Performance

2359.HK vs. NTRA - Performance Comparison

The chart below illustrates the hypothetical performance of a HK$10,000 investment in WuXi AppTec Co Ltd H (2359.HK) and Natera, Inc. (NTRA). The values are adjusted to include any dividend payments, if applicable.

Different Trading Currencies

2359.HK is traded in HKD, while NTRA is traded in USD. To make them comparable, the NTRA values have been converted to HKD using the latest available exchange rates.

Returns By Period

In the year-to-date period, 2359.HK achieves a 30.06% return, which is significantly higher than NTRA's -6.81% return.

2359.HK

• 1D: 2.67%
• 1M: -7.72%
• YTD: 30.06%
• 6M: 22.14%
• 1Y: 64.19%
• 3Y*: 26.47%
• 5Y*: -4.01%
• 10Y*: —

NTRA

• 1D: -3.28%
• 1M: 8.65%
• YTD: -6.81%
• 6M: -7.97%
• 1Y: 28.80%
• 3Y*: 61.11%
• 5Y*: 15.56%
• 10Y*: 33.66%

*Multi-year figures are annualized to reflect compound growth (CAGR)

2359.HK vs. NTRA - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018
2359.HK WuXi AppTec Co Ltd H	30.06%	79.26%	-26.51%	-2.22%	-38.51%	28.35%	208.93%	182.07%	1.47%
NTRA Natera, Inc.	-6.81%	45.00%	151.41%	55.92%	-56.91%	-5.65%	194.07%	140.06%	-17.21%

Correlation

The correlation between 2359.HK and NTRA is -0.08, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	-0.08
Correlation (3Y) Calculated over the trailing 3-year period	-0.01
Correlation (5Y) Calculated over the trailing 5-year period	0.05
Correlation (All Time) Calculated using the full available price history since Dec 13, 2018	0.05

The correlation between 2359.HK and NTRA shifts across timeframes, from -0.08 (1 year) to 0.05 (all time), reflecting how their relationship changes across market environments.

Return for Risk

2359.HK vs. NTRA — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

2359.HK

2359.HK Risk / Return Rank: 81
2359.HK Sharpe Ratio Rank: 81
2359.HK Sortino Ratio Rank: 80
2359.HK Omega Ratio Rank: 76
2359.HK Calmar Ratio Rank: 86
2359.HK Martin Ratio Rank: 82

NTRA

NTRA Risk / Return Rank: 62
NTRA Sharpe Ratio Rank: 65
NTRA Sortino Ratio Rank: 60
NTRA Omega Ratio Rank: 59
NTRA Calmar Ratio Rank: 64
NTRA Martin Ratio Rank: 63

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

2359.HK vs. NTRA - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for WuXi AppTec Co Ltd H (2359.HK) and Natera, Inc. (NTRA). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	2359.HK	NTRA	Difference
Sharpe ratio: Return per unit of total volatility	1.40	0.67	+0.73
Sortino ratio: Return per unit of downside risk	2.15	1.14	+1.01
Omega ratio: Gain probability vs. loss probability	1.25	1.14	+0.11
Calmar ratio: Return relative to maximum drawdown	3.33	1.04	+2.29
Martin ratio: Return relative to average drawdown	6.82	2.19	+4.63

2359.HK vs. NTRA - Sharpe Ratio Comparison

The current 2359.HK Sharpe Ratio is 1.40, which is higher than the NTRA Sharpe Ratio of 0.67. The chart below compares the historical Sharpe Ratios of 2359.HK and NTRA, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

2359.HK vs. NTRA - Drawdown Comparison

The maximum 2359.HK drawdown since its inception was -84.67%, which is greater than NTRA's maximum drawdown of -77.54%. Use the drawdown chart below to compare losses from any high point for 2359.HK and NTRA.

Drawdown Indicators

	2359.HK	NTRA	Difference
Max Drawdown Largest peak-to-trough decline	-84.67%	-77.54%	-7.13%
Max Drawdown (1Y) Largest decline over 1 year	-19.77%	-27.78%	+8.01%
Max Drawdown (3Y) Largest decline over 3 years	-72.09%	-40.13%	-31.96%
Max Drawdown (5Y) Largest decline over 5 years	-84.67%	-77.54%	-7.13%
Max Drawdown (10Y) Largest decline over 10 years	—	-77.54%	—
Current Drawdown Current decline from peak	-26.84%	-16.12%	-10.72%
Average Drawdown Average peak-to-trough decline	-36.43%	-33.31%	-3.12%
Ulcer Index Depth and duration of drawdowns from previous peaks	9.56%	13.19%	-3.63%

Volatility

2359.HK vs. NTRA - Volatility Comparison

The current volatility for WuXi AppTec Co Ltd H (2359.HK) is 11.22%, while Natera, Inc. (NTRA) has a volatility of 14.28%. This indicates that 2359.HK experiences smaller price fluctuations and is considered to be less risky than NTRA based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	2359.HK	NTRA	Difference
Volatility (1M) Calculated over the trailing 1-month period	11.22%	14.28%	-3.06%
Volatility (6M) Calculated over the trailing 6-month period	30.62%	35.18%	-4.56%
Volatility (1Y) Calculated over the trailing 1-year period	47.16%	42.95%	+4.21%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	61.35%	57.02%	+4.33%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	61.02%	60.92%	+0.10%

Dividends

2359.HK vs. NTRA - Dividend Comparison

2359.HK's dividend yield for the trailing twelve months is around 1.73%, while NTRA has not paid dividends to shareholders.

Position	TTM	2025	2024	2023	2022	2021	2020	2019
2359.HK WuXi AppTec Co Ltd H	1.73%	1.84%	1.92%	1.24%	0.75%	0.27%	0.19%	0.82%
NTRA Natera, Inc.	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Financials

Frequently Asked Questions

Can I hold both 2359.HK and NTRA in my portfolio?

2359.HK and NTRA have a correlation of -0.08, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.