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ISIN
US98943L1070
CUSIP
98943L107
IPO Date
Apr 3, 2020

Highlights

Market Cap
$257.87M
Enterprise Value
$260.59M
EPS (TTM)
-$1.74
Gross Profit (TTM)
-$157.00K
EBITDA (TTM)
-$136.37M
Year Range
$1.13 - $6.95
Target Price
$10.00
ROA (TTM)
-49.05%
ROE (TTM)
-67.95%

Share Price Chart


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Zentalis Pharmaceuticals, Inc.

Performance

ZNTL Performance Chart

Zentalis Pharmaceuticals, Inc. (ZNTL) is up 171.9% since the beginning of the year. At $4 per share, ZNTL is trading 47.2% below its 52-week high of $7. Investors who bought $1,000 worth of ZNTL shares 5 years ago would now be looking at an investment worth $70.


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S&P 500 Index

Returns By Period

Zentalis Pharmaceuticals, Inc. (ZNTL) has returned 171.85% so far this year and 182.31% over the past 12 months.


Zentalis Pharmaceuticals, Inc.

1D
-0.81%
1M
-9.61%
YTD
171.85%
6M
162.14%
1Y
182.31%
3Y*
-49.79%
5Y*
-41.23%
10Y*

Benchmark (S&P 500 Index)

1D
-0.37%
1M
-0.01%
YTD
9.16%
6M
8.64%
1Y
25.22%
3Y*
19.78%
5Y*
11.99%
10Y*
13.88%
*Multi-year figures are annualized to reflect compound growth (CAGR)

ZNTL Monthly Returns History

Based on dividend-adjusted daily data since Apr 3, 2020, ZNTL's average daily return is +0.04%, while the average monthly return is +0.39%. At this rate, an investment would double in approximately 14.8 years.

Historically, 41% of months were positive and 59% were negative. The best month was Jan 2026 with a return of +80.0%, while the worst month was Jun 2024 at -65.6%. The longest winning streak lasted 3 consecutive months, and the longest losing streak was 5 months.

On a daily basis, ZNTL closed higher 48% of trading days. The best single day was Apr 9, 2026 with a return of +60.1%, while the worst single day was Jun 18, 2024 at -50.7%.


JanFebMarAprMayJunJulAugSepOctNovDecTotal
202680.00%-1.65%-2.09%71.37%-0.25%-8.25%171.85%
2025-42.57%18.97%-23.19%-10.69%-14.79%-4.13%18.97%22.46%-10.65%-0.66%-4.67%-5.59%-55.45%
2024-21.78%25.82%5.70%-29.82%7.41%-65.57%-4.89%-10.80%6.05%-25.82%32.23%-16.07%-80.00%
202317.18%-19.79%-9.14%28.08%18.20%8.33%-5.32%-0.56%-24.47%-18.44%-31.23%34.67%-24.78%
2022-32.10%-12.60%-7.52%-42.52%-9.09%16.55%3.91%-8.18%-19.21%15.84%-11.84%-8.95%-76.04%
2021-26.13%9.56%3.21%36.71%-5.85%-4.74%0.02%28.15%-2.27%20.71%2.00%2.45%61.84%

Benchmark Metrics

Zentalis Pharmaceuticals, Inc. has an annualized alpha of -17.58%, beta of 1.55, and R2 of 0.09 versus S&P 500 Index. Calculated based on daily prices since April 03, 2020.

  • This stock participated in 222.14% of S&P 500 Index downside but only 67.25% of its upside - more exposed to losses than it benefited from rallies.
  • R2 of 0.09 means this stock moves largely independently of S&P 500 Index - capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.

Alpha
-17.58%
Beta
1.55
0.09
Upside Capture
67.25%
Downside Capture
222.14%

Return for Risk

Risk / Return Rank

ZNTL ranks 85 for risk / return — in the top 85% of stocks on our site. This means strong returns relative to risk — exactly what professional investors look for. Well-suited for investors who want to maximize return per unit of risk.


ZNTL Risk / Return Rank: 8585
Overall Rank
ZNTL Sharpe Ratio Rank: 8282
Sharpe Ratio Rank
ZNTL Sortino Ratio Rank: 8989
Sortino Ratio Rank
ZNTL Omega Ratio Rank: 8686
Omega Ratio Rank
ZNTL Calmar Ratio Rank: 8888
Calmar Ratio Rank
ZNTL Martin Ratio Rank: 8181
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

Return / Risk — by metrics

The table below present risk-adjusted performance metrics for Zentalis Pharmaceuticals, Inc. (ZNTL) and compare them to S&P 500 Index.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.


ZNTLBenchmarkDifference
Sharpe ratioReturn per unit of total volatility

-0.57

Sortino ratioReturn per unit of downside risk

+0.20

Omega ratioGain probability vs. loss probability

1.36

1.37

-0.01

Calmar ratioReturn relative to maximum drawdown

3.92

2.78

+1.14

Martin ratioReturn relative to average drawdown

6.54

12.44

-5.90

Dividends

Dividend History


Zentalis Pharmaceuticals, Inc. doesn't pay dividends

Drawdowns

Drawdowns Chart

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.


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Worst Drawdowns

The table below displays the maximum drawdowns of the Zentalis Pharmaceuticals, Inc.. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the Zentalis Pharmaceuticals, Inc. was 98.77%, occurring on Apr 8, 2025. The portfolio has not yet recovered.

The current Zentalis Pharmaceuticals, Inc. drawdown is 95.67%.


Related event

Drawdown

Fall

Recovery

Underwater

2025 selloff2025
-98.77%Apr 2025
3y 5mo
4y 7moNov 2021 - now
2020 bear market2020
-50.68%Sep 2020
2mo 10d3mo 5d
5mo 15dJun 2020 - Dec 2020
2021 bear market2021
-38.43%Feb 2021
2mo 11d2mo 4d
4mo 15dDec 2020 - Apr 2021
2021 bear market2021
-24.77%Jul 2021
2mo 10d1mo 20d
4moApr 2021 - Aug 2021
2020 bear market2020
-21.35%Jun 2020
10d6d
16dJun 2020 - Jun 2020

Drawdown Indicators


ZNTLBenchmarkDifference

Max Drawdown

Largest peak-to-trough decline

-98.77%

-56.78%

-41.99%

Max Drawdown (1Y)

Largest decline over 1 year

-46.75%

-9.10%

-37.65%

Max Drawdown (3Y)

Largest decline over 3 years

-96.41%

-18.90%

-77.51%

Max Drawdown (5Y)

Largest decline over 5 years

-98.77%

-25.43%

-73.34%

Max Drawdown (10Y)

Largest decline over 10 years

-33.92%

Current Drawdown

Current decline from peak

-95.67%

-1.80%

-93.87%

Average Drawdown

Average peak-to-trough decline

-64.32%

-10.71%

-53.61%

Ulcer Index

Depth and duration of drawdowns from previous peaks

28.01%

2.03%

+25.98%

Volatility

Volatility Chart

The chart below shows the rolling one-month volatility.


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Financials

Financial Performance

The chart below illustrates the trends in the financial health of Zentalis Pharmaceuticals, Inc. over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.


Annual
Quarterly

0.0

Valuation

The Valuation section provides an overview of how Zentalis Pharmaceuticals, Inc. is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.


PB Ratio

The chart illustrates the Price-to-Book (P/B) ratio for ZNTL in comparison with other companies in the Biotechnology industry. Currently, ZNTL has a P/B value of 1.4. This P/B ratio is in line with the industry average, suggesting the stock is valued fairly in relation to its book value.

Income Statement



TTM
Revenue

Total Revenue

Cost Of Revenue

Gross Profit

Operating Expenses

Selling, General & Admin Expenses

R&D Expenses

Depreciation And Amortization

Total Operating Expenses

Income

Income Before Tax

Operating Income

EBITDA

EBIT

Earnings From Continuing Operations

Net Income

Income Tax Expense

Other Non-Operating Income (Expenses)

Extraordinary Items

Discontinued Operations

Effect Of Accounting Charges

Non Recurring

Minority Interest

Other Items

Interest Income

Interest Expense

Net Interest Income

Values in undefined except per share items
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