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VNDA's Sortino Ratio of 1.25 indicates that for each unit of downside volatility, it generates 1.25 units of excess return. The ratio is calculated using historical daily returns over the past 12 months (as of Jun 23, 2026).

Unlike other measures, Sortino only focuses on downside volatility (losses), making it particularly useful for investors more concerned about protecting against drawdowns than overall price swings.

VNDA Sortino Ratio Rank


VNDA Sortino Ratio Rank: 61.361
Above Average

VNDA ranks above 61.3% of all investments in our database based on Sortino Ratio over the past 12 months, indicating above-average returns relative to downside risk taken. Securities are ranked from 0 (worst) to 100 (best).

What moves the rank

  • Strong returns with minimal downside volatility → Higher rank
  • Severe or frequent drawdowns → Lower rank
  • Upside volatility → No impact (Sortino doesn't penalize upside swings)

What you can do with this information

  • Above-average downside protection with room for improvement
  • Compare against category peers to gauge relative positioning
  • Monitor for movement toward top tier or decline toward median
  • Consider pairing with top-tier holdings to improve portfolio risk profile

VNDA Sortino Ratio Market Positioning

The chart shows VNDA's Sortino Ratio relative to all stocks on our platform, with color zones indicating percentile rankings. Higher ratios indicate better downside-adjusted returns.


  • Red zone (bottom 25%): -0.29 or lower
  • Yellow zone (middle 50%): -0.29 to 1.94
  • Green zone (top 25%): 1.94 or higher
  • Top 1%: 6.39+
  • Median: 0.76 — half of all investments score higher

How it compares to other similar stocks

The table compares Vanda Pharmaceuticals Inc.'s Sortino Ratio with other stocks in the Biotechnology industry across multiple time periods, showing how VNDA's risk-adjusted performance compares to industry peers.

Data shows 1-, 5-, and 10-year periods, plus each stock's all-time average, as of Jun 23, 2026.


SymbolName1Y Sortino Ratio5Y Sortino Ratio10Y Sortino RatioAll Time Sortino Ratio
CARMCarisma Therapeutics Inc.77.79
ABVXAbivax SA American Depositary Shares13.18
INKTMiNK Therapeutics, Inc.8.54
NKGNNKGen Biotech Inc. Common Stock7.53
PROKProKidney Corp.7.52
COGTCogent Biosciences, Inc.7.27
NKTRNektar Therapeutics6.83
PRAXPraxis Precision Medicines, Inc.6.70
ALMSAlumis Inc6.47
SYRESpyre Therapeutics Inc.6.29
VNDAVanda Pharmaceuticals Inc.1.25

S&P 500 Index

How to choose period

Historical Sortino Ratio

The chart shows VNDA's rolling Sortino ratio over time compared to your chosen benchmark. Rising trends indicate improving returns relative to downside risk, while declining trends may signal deteriorating risk-adjusted performance or increased volatility during market stress. Use multiple timeframes to distinguish short-term fluctuations from long-term patterns.

Identify market cycles by observing when VNDA consistently outperforms (line above benchmark), underperforms (below benchmark), or aligns with the benchmark.


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