Talphera Inc (TLPH)

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Talphera Inc (TLPH) is down 32.0% since the beginning of the year. At $1 per share, TLPH is trading 50.6% below its 52-week high of $2. Investors who bought $1,000 worth of TLPH shares 5 years ago would now be looking at an investment worth $27.

Talphera Inc (TLPH) has returned -31.99% so far this year and 62.84% over the past 12 months. Over the last ten years, TLPH has returned -36.26% per year, falling short of the S&P 500 Index benchmark, which averaged 13.75% annually.

Based on dividend-adjusted daily data since Feb 11, 2011, TLPH's average daily return is +0.03%, while the average monthly return is +0.12%. At this rate, an investment would double in approximately 48.2 years.

Historically, 44% of months were positive and 56% were negative. The best month was Jul 2017 with a return of +81.4%, while the worst month was Oct 2017 at -58.7%. The longest winning streak lasted 5 consecutive months, and the longest losing streak was 12 months.

On a daily basis, TLPH closed higher 43% of trading days. The best single day was Jan 12, 2021 with a return of +60.3%, while the worst single day was Oct 12, 2017 at -59.8%.

Talphera Inc has an annualized alpha of -5.19%, beta of 0.90, and R2 of 0.03 versus S&P 500 Index. Calculated based on daily prices since February 14, 2011.

• This stock participated in 201.87% of S&P 500 Index downside but only 26.46% of its upside - more exposed to losses than it benefited from rallies.
• R2 of 0.03 means this stock moves largely independently of S&P 500 Index - capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.

TLPH ranks 65 for risk / return — better than 65% of stocks on our site. You're getting solid returns for the risk taken. A good sign, especially for investors who want growth without excessive volatility.

The table below present risk-adjusted performance metrics for Talphera Inc (TLPH) and compare them to S&P 500 Index.

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.

The table below displays the maximum drawdowns of the Talphera Inc. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the Talphera Inc was 99.85%, occurring on Aug 7, 2025. The portfolio has not yet recovered.

The current Talphera Inc drawdown is 99.70%.

The chart below shows the rolling one-month volatility.

The chart below illustrates the trends in the financial health of Talphera Inc over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.

The Valuation section provides an overview of how Talphera Inc is priced in the market compared to other companies in the Drug Manufacturers - Specialty & Generic industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.