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SPDR MSCI Europe Health Care UCITS ETF (SPYH.DE) Alternatives

ETF · Currency in EUR · Last updated Jun 5, 2026

SPYH.DE is a passive ETF by State Street tracking the investment results of the MSCI Europe Health Care 20/35 Capped. SPYH.DE launched on Dec 5, 2014 and has a 0.18% expense ratio.

SPDR MSCI Europe Health Care UCITS ETF (SPYH.DE) belongs to the Health & Biotech Equities category. Below you'll find alternative ETFs from the same category, ranked by key criteria, plus funds that investors commonly compare with SPYH.DE. Use the tables to find lower-cost options, better risk-adjusted returns, or a closer substitute for your current allocation.

Cheapest Alternatives to SPYH.DE

SPYH.DE charges 0.18% annually. There are 4 ETFs in the Health & Biotech Equities category with lower expense ratios, going as low as 0.12%.

SymbolNameExpense RatioAUMInception
XUHC.DE
Xtrackers MSCI USA Health Care UCITS ETF 1D0.12%—Sep 2017SPYH.DE vs XUHC.DE
QDVG.DE
iShares S&P 500 Health Care Sector UCITS ETF (Acc)0.15%—Nov 2015SPYH.DE vs QDVG.DE
ZPDH.DE
SPDR S&P US Health Care Select Sector UCITS ETF0.15%—Jul 2015SPYH.DE vs ZPDH.DE
DXSE.DE
Xtrackers MSCI Europe Health Care ESG Screened UCI...0.17%—Jun 2007SPYH.DE vs DXSE.DE
CBUF.DE
iShares MSCI World Health Care Sector ESG UCITS ET...0.18%—Oct 2019SPYH.DE vs CBUF.DE

Best Risk-Adjusted Alternatives to SPYH.DE

SPYH.DE has a PortfoliosLab risk / return rank of 15. There are 18 ETFs in the Health & Biotech Equities category with higher risk-adjusted ranks, going as high as 71.

SymbolNameRisk / Return RankAUMInception
2B70.DE
iShares Nasdaq US Biotechnology UCITS ETF
71
—Oct 2017SPYH.DE vs 2B70.DE
NBTK.DE
Invesco Nasdaq Biotech UCITS ETF
71
—Nov 2014SPYH.DE vs NBTK.DE
GN0M.DE
Global X Genomics & Biotechnology UCITS ETF
58
—Nov 2021SPYH.DE vs GN0M.DE
WRNA.DE
WisdomTree BioRevolution UCITS ETF USD Acc
56
—Dec 2021SPYH.DE vs WRNA.DE
2B77.DE
iShares Ageing Population UCITS ETF
43
—Sep 2016SPYH.DE vs 2B77.DE

Top Performing SPYH.DE Alternatives (YTD)

SPYH.DE is at -1.97% YTD. There are 12 ETFs in the Health & Biotech Equities category with higher YTD returns, going as high as 12.99%.

SymbolNameYTD ReturnAUMInception
GN0M.DE
Global X Genomics & Biotechnology UCITS ETF
12.99%
—Nov 2021SPYH.DE vs GN0M.DE
WRNA.DE
WisdomTree BioRevolution UCITS ETF USD Acc
10.48%
—Dec 2021SPYH.DE vs WRNA.DE
2B70.DE
iShares Nasdaq US Biotechnology UCITS ETF
4.53%
—Oct 2017SPYH.DE vs 2B70.DE
NBTK.DE
Invesco Nasdaq Biotech UCITS ETF
4.27%
—Nov 2014SPYH.DE vs NBTK.DE
2B77.DE
iShares Ageing Population UCITS ETF
2.83%
—Sep 2016SPYH.DE vs 2B77.DE

Lowest Volatility Alternatives to SPYH.DE

SPYH.DE has 17.05% 1-year volatility. There are 17 ETFs in the Health & Biotech Equities category with lower 1-year volatility, going as low as 12.28%.

SymbolNameVolatility 1YAUMInception
2B77.DE
iShares Ageing Population UCITS ETF12.28%—Sep 2016SPYH.DE vs 2B77.DE
XDWH.DE
Xtrackers MSCI World Health Care UCITS ETF 1C13.69%—Mar 2016SPYH.DE vs XDWH.DE
LYPE.DE
Amundi MSCI World Health Care UCITS ETF EUR Acc13.82%—Aug 2010SPYH.DE vs LYPE.DE
CBUF.DE
iShares MSCI World Health Care Sector ESG UCITS ET...13.98%—Oct 2019SPYH.DE vs CBUF.DE
XUHC.DE
Xtrackers MSCI USA Health Care UCITS ETF 1D14.51%—Sep 2017SPYH.DE vs XUHC.DE

Lowest Drawdown Alternatives to SPYH.DE

SPYH.DE has a 1-year max drawdown of -12.58%. There are 17 ETFs in the Health & Biotech Equities category with shallower 1-year drawdowns, going as shallow as -6.24%.

SymbolNameMax Drawdown 1YAUMInception
NBTK.DE
Invesco Nasdaq Biotech UCITS ETF
-6.24%
—Nov 2014SPYH.DE vs NBTK.DE
2B70.DE
iShares Nasdaq US Biotechnology UCITS ETF
-6.33%
—Oct 2017SPYH.DE vs 2B70.DE
2B77.DE
iShares Ageing Population UCITS ETF
-6.80%
—Sep 2016SPYH.DE vs 2B77.DE
ETLI.DE
L&G Pharma Breakthrough UCITS ETF
-9.06%
—Jan 2018SPYH.DE vs ETLI.DE
LYPE.DE
Amundi MSCI World Health Care UCITS ETF EUR Acc
-10.21%
—Aug 2010SPYH.DE vs LYPE.DE

Other ETFs from State Street

The 10 most viewed State Street ETFs shown here include SPYL.DE, SPYY.DE, ZPRV.DE and span 7 categories.

SymbolNameCategoryRisk / Return RankYTD ReturnAUMInception
SPYL.DE
State Street SPDR S&P 500 UCITS ETF USD Unhedged (...S&P 500, Large Cap Blend Equities
69
11.37%
—Oct 2023SPYH.DE vs SPYL.DE
SPYY.DE
SPDR MSCI ACWI UCITS ETFGlobal Equities
77
12.54%
—May 2011SPYH.DE vs SPYY.DE
ZPRV.DE
SPDR MSCI USA Small Cap Value Weighted UCITS ETFSmall Cap Value Equities
74
14.58%
—Feb 2015SPYH.DE vs ZPRV.DE
SPYI.DE
SPDR MSCI ACWI IMI UCITS ETFGlobal Equities
79
13.27%
—May 2011SPYH.DE vs SPYI.DE
SPPW.DE
SPDR MSCI World UCITS ETFGlobal Equities
70
10.85%
—Feb 2019SPYH.DE vs SPPW.DE
SPY5.DE
SPDR S&P 500 UCITS ETFS&P 500
69
11.39%
—Mar 2012SPYH.DE vs SPY5.DE
ZPRX.DE
SPDR MSCI Europe Small Cap Value Weighted UCITS ET...Europe Equities
34
7.81%
—Feb 2015SPYH.DE vs ZPRX.DE
SPYW.DE
SPDR S&P Euro Dividend Aristocrats UCITS ETF (Dist...Europe Equities
22
5.36%
—Feb 2012SPYH.DE vs SPYW.DE
SPYM.DE
SPDR MSCI Emerging Markets UCITS ETFEmerging Markets Equities
85
27.39%
—May 2011SPYH.DE vs SPYM.DE
SPPY.DE
State Street SPDR S&P 500 Leaders UCITS ETFS&P 500, ESG
78
11.08%
—Dec 2019SPYH.DE vs SPPY.DE

Often Compared With SPYH.DE

Investors most often compare SPYH.DE with SPYI, SPY, EXV4.DE. These 20 comparison targets span 6 categories, based on PortfoliosLab usage data.

SymbolNameCategoryRisk / Return RankYTD ReturnAUMInception
SPYI
NEOS S&P 500 High Income ETFDerivative Income, S&P 500
66
5.65%
10.07BAug 2022SPYH.DE vs SPYI
SPY
State Street SPDR S&P 500 ETFS&P 500
66
8.45%
781.00BJan 1993SPYH.DE vs SPY
EXV4.DE
iShares STOXX Europe 600 Health Care UCITS ETF (DE...Health & Biotech Equities
13
-2.60%
—Apr 2001SPYH.DE vs EXV4.DE
XNAS.DE
Xtrackers Nasdaq 100 UCITS ETF 1CNasdaq-100
71
20.53%
—Jan 2021SPYH.DE vs XNAS.DE
^STOXX
STOXX Europe 600 Index
45
5.45%
——SPYH.DE vs ^STOXX
MSTR
Strategy Inc
7
-20.74%
——SPYH.DE vs MSTR
VOO
Vanguard S&P 500 ETFS&P 500
66
8.45%
1.60TSep 2010SPYH.DE vs VOO
SPYV.DE
SPDR S&P Emerging Markets Dividend Aristocrats UCI...Emerging Markets Equities
26
5.71%
—Oct 2011SPYH.DE vs SPYV.DE
NFLY
YieldMax NFLX Option Income Strategy ETFDerivative Income
2
-8.18%
52.62MAug 2023SPYH.DE vs NFLY
VJPU.L
Vanguard FTSE Japan UCITS ETF USD Hedged AccJapan Equities
88
19.64%
4.45BJan 2020SPYH.DE vs VJPU.L
DDOC.DE
Global X Telemedicine & Digital Health UCITS ETF A...Health & Biotech Equities
9
-1.35%
—Dec 2020SPYH.DE vs DDOC.DE
SC0T.DE
Invesco European Health Care Sector UCITS ETFHealth & Biotech Equities
12
-3.57%
—Jul 2009SPYH.DE vs SC0T.DE
WELS.DE
Amundi S&P Global Health Care ESG UCITS ETF EUR Ac...Health & Biotech Equities
16
-3.35%
—Sep 2022SPYH.DE vs WELS.DE
ESIH.DE
iShares MSCI Europe Health Care Sector UCITS ETF E...Health & Biotech Equities
15
-2.35%
—Nov 2020SPYH.DE vs ESIH.DE
WELG.DE
Amundi S&P Global Health Care ESG UCITS ETF EUR Di...Health & Biotech Equities
16
-3.60%
—Sep 2022SPYH.DE vs WELG.DE
XGEN.DE
Xtrackers MSCI Genomic Healthcare Innovation UCITS...Health & Biotech Equities
32
-1.40%
—Jul 2022SPYH.DE vs XGEN.DE
EHLT.DE
Lyxor STOXX Europe 600 Healthcare UCITS ETF DistHealth & Biotech Equities
14
-2.49%
—Jul 2020SPYH.DE vs EHLT.DE
2B78.DE
iShares Healthcare Innovation UCITS ETFHealth & Biotech Equities
26
-2.07%
—Sep 2016SPYH.DE vs 2B78.DE
XDG3.DE
Xtrackers MSCI Global SDG 3 Good Health UCITS ETF ...Health & Biotech Equities
11
-6.02%
—Jan 2023SPYH.DE vs XDG3.DE
W311.DE
HANetf HAN-GINS Indxx Healthcare Megatrend Equal W...Health & Biotech Equities
18
-3.63%
—Apr 2019SPYH.DE vs W311.DE

Compare SPYH.DE with Any Fund or Stock

Compare SPYH.DE with any ETF, mutual fund, or stock using PortfoliosLab's comparison tool.

 

Diversifiers

Pair SPYH.DE with funds that move differently

SPDR MSCI Europe Health Care UCITS ETF alternatives help with substitution. Diversifiers are the next step when you want funds with lower historical correlation to SPYH.DE.

Explore SPYH.DE Diversifiers