Sera Prognostics, Inc. (SERA)

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The chart shows the growth of an initial investment of $10,000 in Sera Prognostics, Inc., comparing it to the performance of the S&P 500 index or another benchmark. All prices have been adjusted for splits and dividends.

Sera Prognostics, Inc. (SERA) has returned -31.19% so far this year and -44.84% over the past 12 months.

Based on dividend-adjusted daily data since Jul 15, 2021, SERA's average daily return is +0.10%, while the average monthly return is +2.15%. At this rate, your investment would double in approximately 2.7 years.

Historically, 40% of months were positive and 60% were negative. The best month was Dec 2023 with a return of +208.3%, while the worst month was May 2025 at -46.9%. The longest winning streak lasted 6 consecutive months, and the longest losing streak was 6 months.

On a daily basis, SERA closed higher 44% of trading days. The best single day was Dec 6, 2023 with a return of +161.4%, while the worst single day was Jun 30, 2025 at -32.3%.

Sera Prognostics, Inc. has an annualized alpha of 17.59%, beta of 0.86, and R² of 0.01 versus S&P 500 Index. Calculated based on daily prices since July 16, 2021.

• This stock participated in 137.23% of S&P 500 Index downside but only -25.93% of its upside — more exposed to losses than it benefited from rallies.
• R² of 0.01 means this stock moves largely independently of S&P 500 Index — capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.

SERA ranks 25 for risk / return — below 25% of stocks on our site. The returns aren't fully compensating for the risk involved. This isn't necessarily a dealbreaker, but factor it into your decision — especially if you're risk-averse.

The table below present risk-adjusted performance metrics for Sera Prognostics, Inc. (SERA) and compare them to a chosen benchmark (S&P 500 Index).

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.

The table below displays the maximum drawdowns of the Sera Prognostics, Inc.. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the Sera Prognostics, Inc. was 91.10%, occurring on Dec 28, 2022. The portfolio has not yet recovered.

The current Sera Prognostics, Inc. drawdown is 84.43%.

The chart below shows the rolling one-month volatility.

The chart below illustrates the trends in the financial health of Sera Prognostics, Inc. over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.

The Valuation section provides an overview of how Sera Prognostics, Inc. is priced in the market compared to other companies in the Diagnostics & Research industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.