- ISIN
- US81749D1072
- CUSIP
- 81749D107
- Sector
- Healthcare
- Industry
- Diagnostics & Research
- IPO Date
- Jul 15, 2021
Highlights
- Market Cap
- $92.98M
- Enterprise Value
- $91.31M
- EPS (TTM)
- -$0.65
- Total Revenue (TTM)
- $57.00K
- Gross Profit (TTM)
- -$109.00K
- EBITDA (TTM)
- -$36.96M
- Year Range
- $1.56 - $4.09
- Target Price
- $5.00
- ROA (TTM)
- -34.36%
- ROE (TTM)
- -47.53%
Share Price Chart
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Performance
SERA Performance Chart
Sera Prognostics, Inc. (SERA) is down 37.3% since the beginning of the year. At $2 per share, SERA is trading 54.8% below its 52-week high of $4.
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Returns By Period
Sera Prognostics, Inc. (SERA) has returned -37.29% so far this year and -3.65% over the past 12 months.
Sera Prognostics, Inc.
- 1D
- 5.71%
- 1M
- -10.63%
- YTD
- -37.29%
- 6M
- -48.61%
- 1Y
- -3.65%
- 3Y*
- -22.54%
- 5Y*
- —
- 10Y*
- —
Benchmark (S&P 500 Index)
- 1D
- -0.37%
- 1M
- -0.01%
- YTD
- 9.16%
- 6M
- 8.64%
- 1Y
- 25.22%
- 3Y*
- 19.78%
- 5Y*
- 11.99%
- 10Y*
- 13.88%
SERA Monthly Returns History
Based on dividend-adjusted daily data since Jul 15, 2021, SERA's average daily return is +0.08%, while the average monthly return is +1.60%. At this rate, an investment would double in approximately 3.6 years.
Historically, 40% of months were positive and 60% were negative. The best month was Dec 2023 with a return of +208.3%, while the worst month was May 2025 at -46.9%. The longest winning streak lasted 6 consecutive months, and the longest losing streak was 6 months.
On a daily basis, SERA closed higher 44% of trading days. The best single day was Dec 6, 2023 with a return of +161.4%, while the worst single day was Jun 30, 2025 at -32.3%.
| Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec | Total | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026 | -6.44% | -17.03% | -11.35% | -4.43% | 11.34% | -14.35% | -37.29% | ||||||
| 2025 | -20.52% | -34.47% | -13.21% | -20.11% | -46.94% | 77.56% | 0.36% | 16.19% | -5.26% | 7.19% | 1.52% | -11.41% | -63.76% |
| 2024 | 17.06% | 27.43% | 2.02% | 28.46% | -23.01% | -34.22% | 40.03% | -11.34% | 6.12% | -1.41% | -12.35% | 20.77% | 36.12% |
| 2023 | 20.63% | 140.79% | 4.64% | -12.53% | -3.58% | 2.01% | -11.08% | -39.25% | 4.49% | -9.14% | 14.79% | 208.25% | 374.60% |
| 2022 | -1.75% | -20.59% | -29.29% | -39.31% | -39.57% | 17.99% | 39.02% | -7.89% | -23.81% | -3.75% | -12.99% | -5.97% | -81.66% |
| 2021 | -25.18% | -11.40% | 11.66% | -7.02% | 2.61% | -35.19% | -54.23% |
Benchmark Metrics
Sera Prognostics, Inc. has an annualized alpha of 9.10%, beta of 0.84, and R2 of 0.01 versus S&P 500 Index. Calculated based on daily prices since July 15, 2021.
- This stock participated in 146.66% of S&P 500 Index downside but only -31.05% of its upside - more exposed to losses than it benefited from rallies.
- R2 of 0.01 means this stock moves largely independently of S&P 500 Index - capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.
- Alpha
- 9.10%
- Beta
- 0.84
- R²
- 0.01
- Upside Capture
- -31.05%
- Downside Capture
- 146.66%
Return for Risk
Risk / Return Rank
SERA ranks 47 for risk / return — on par with similar stocks. You're getting a typical balance of risk and reward. Not a standout, but not a red flag either — a reasonable choice if other factors align with your goals.
Return / Risk — by metrics
The table below present risk-adjusted performance metrics for Sera Prognostics, Inc. (SERA) and compare them to S&P 500 Index.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| SERA | Benchmark | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -2.06 | ||
| Sortino ratioReturn per unit of downside risk | -1.63 | ||
| Omega ratioGain probability vs. loss probability | 1.13 | 1.37 | -0.23 |
| Calmar ratioReturn relative to maximum drawdown | -0.06 | 2.78 | -2.84 |
| Martin ratioReturn relative to average drawdown | -0.10 | 12.44 | -12.54 |
Dividends
Dividend History
Drawdowns
Drawdowns Chart
The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.
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Worst Drawdowns
The table below displays the maximum drawdowns of the Sera Prognostics, Inc.. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.
The maximum drawdown for the Sera Prognostics, Inc. was 92.27%, occurring on Dec 28, 2022. The portfolio has not yet recovered.
The current Sera Prognostics, Inc. drawdown is 87.67%.
Related event | Drawdown | Fall | Recovery | Underwater |
|---|---|---|---|---|
Bear market2022 | -92.27%Dec 2022 | 1y 5mo | — | 4y 11moJul 2021 - now |
Drawdown Indicators
| SERA | Benchmark | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -92.27% | -56.78% | -35.49% |
Max Drawdown (1Y)Largest decline over 1 year | -61.12% | -9.10% | -52.02% |
Max Drawdown (3Y)Largest decline over 3 years | -87.25% | -18.90% | -68.35% |
Max Drawdown (5Y)Largest decline over 5 years | — | -25.43% | — |
Max Drawdown (10Y)Largest decline over 10 years | — | -33.92% | — |
Current DrawdownCurrent decline from peak | -87.67% | -1.80% | -85.87% |
Average DrawdownAverage peak-to-trough decline | -69.25% | -10.71% | -58.54% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 36.66% | 2.03% | +34.63% |
Volatility
Volatility Chart
The chart below shows the rolling one-month volatility.
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Financials
Financial Performance
The chart below illustrates the trends in the financial health of Sera Prognostics, Inc. over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.
Valuation
The Valuation section provides an overview of how Sera Prognostics, Inc. is priced in the market compared to other companies in the Diagnostics & Research industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.
PS Ratio
This chart shows the Price-to-Sales (P/S) ratio for SERA relative to other companies in the Diagnostics & Research industry. Currently, SERA has a P/S ratio of 1,613.3. This P/S ratio is high relative to other companies in the industry. It could mean the stock is overvalued, or that investors expect strong future growth and profitability.
PB Ratio
The chart illustrates the Price-to-Book (P/B) ratio for SERA in comparison with other companies in the Diagnostics & Research industry. Currently, SERA has a P/B value of 1.4. This P/B ratio is in line with the industry average, suggesting the stock is valued fairly in relation to its book value.
Income Statement
| TTM | |
|---|---|
Revenue | — |
Total Revenue | — |
Cost Of Revenue | — |
Gross Profit | — |
Operating Expenses | — |
Selling, General & Admin Expenses | — |
R&D Expenses | — |
Depreciation And Amortization | — |
Total Operating Expenses | — |
Income | — |
Income Before Tax | — |
Operating Income | — |
EBITDA | — |
EBIT | — |
Earnings From Continuing Operations | — |
Net Income | — |
Income Tax Expense | — |
Other Non-Operating Income (Expenses) | — |
Extraordinary Items | — |
Discontinued Operations | — |
Effect Of Accounting Charges | — |
Non Recurring | — |
Minority Interest | — |
Other Items | — |
Interest Income | — |
Interest Expense | — |
Net Interest Income | — |
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