Rein Therapeutics Inc (RNTX)

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Rein Therapeutics Inc (RNTX) is down 11.2% since the beginning of the year. At $1 per share, RNTX is trading 52.8% below its 52-week high of $2. Investors who bought $1,000 worth of RNTX shares 5 years ago would now be looking at an investment worth $39.

Rein Therapeutics Inc (RNTX) has returned -11.21% so far this year and -46.63% over the past 12 months. Over the last ten years, RNTX has returned -7.48% per year, falling short of the S&P 500 Index benchmark, which averaged 13.75% annually.

Based on dividend-adjusted daily data since Mar 12, 1986, RNTX's average daily return is +1.12%, while the average monthly return is +21.45%. At this rate, an investment would double in approximately 0.3 years.

Historically, 40% of months were positive and 60% were negative. The best month was Jun 2017 with a return of +9,846.5%, while the worst month was Dec 2018 at -61.3%. The longest winning streak lasted 8 consecutive months, and the longest losing streak was 7 months.

On a daily basis, RNTX closed higher 27% of trading days. The best single day was Jun 29, 2017 with a return of +9,534.3%, while the worst single day was Apr 25, 2013 at -64.2%.

Rein Therapeutics Inc has an annualized alpha of 1543.39%, beta of -0.01, and R2 of 0.00 versus S&P 500 Index. Calculated based on daily prices since March 13, 1986.

• This stock participated in 119.90% of S&P 500 Index downside but only 60.84% of its upside - more exposed to losses than it benefited from rallies.
• Beta of -0.01 may look defensive, but with R2 of 0.00 this stock is largely uncorrelated with S&P 500 Index - low beta reflects independence, not downside protection. See the Volatility section for a true picture of this stock's risk.
• R2 of 0.00 means this stock moves largely independently of S&P 500 Index - capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.

RNTX ranks 16 for risk / return — in the bottom 16% of stocks on our site. This means you're taking on significantly more risk than the returns justify. Consider whether the potential upside is worth the volatility, or explore alternatives with better risk / return profiles.

The table below present risk-adjusted performance metrics for Rein Therapeutics Inc (RNTX) and compare them to S&P 500 Index.

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.

The table below displays the maximum drawdowns of the Rein Therapeutics Inc. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the Rein Therapeutics Inc was 99.81%, occurring on May 20, 2026. The portfolio has not yet recovered.

The current Rein Therapeutics Inc drawdown is 99.80%.

The chart below shows the rolling one-month volatility.

The chart below illustrates the trends in the financial health of Rein Therapeutics Inc over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.

The Valuation section provides an overview of how Rein Therapeutics Inc is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.