PortfoliosLab logoPortfoliosLab logo

PainReform Ltd. (PRFX) Sortino Ratio: -1.58

PRFX's Sortino Ratio of -1.58 indicates that for each unit of downside volatility, it generates -1.58 units of excess return. The ratio is calculated using historical daily returns over the past 12 months (as of Apr 1, 2026).

Unlike other measures, Sortino only focuses on downside volatility (losses), making it particularly useful for investors more concerned about protecting against drawdowns than overall price swings.

PRFX Sortino Ratio Rank


PRFX Sortino Ratio Rank: 4.75
Concerning

PRFX ranks above 4.7% of all investments in our database based on Sortino Ratio over the past 12 months, indicating weak returns relative to downside risk taken. Securities are ranked from 0 (worst) to 100 (best).

What moves the rank

  • Strong returns with minimal downside volatility → Higher rank
  • Severe or frequent drawdowns → Lower rank
  • Upside volatility → No impact (Sortino doesn't penalize upside swings)

What you can do with this information

  • Weak downside-adjusted returns relative to category peers
  • Evaluate whether this holding aligns with your risk-return objectives
  • Consider reducing exposure or implementing downside hedges
  • Review higher-ranked alternatives in the same category

PRFX Sortino Ratio Market Positioning

The chart shows PRFX's Sortino Ratio relative to all stocks on our platform, with color zones indicating percentile rankings. Higher ratios indicate better downside-adjusted returns.


  • Red zone (bottom 25%): -0.18 or lower
  • Yellow zone (middle 50%): -0.18 to 1.88
  • Green zone (top 25%): 1.88 or higher
  • Top 1%: 5.63+
  • Median: 0.83 — half of all investments score higher

How it compares to other similar stocks

The table compares PainReform Ltd.'s Sortino Ratio with other stocks in the Drug Manufacturers - Specialty & Generic industry across multiple time periods, showing how PRFX's risk-adjusted performance compares to industry peers.

Data shows 1-, 5-, and 10-year periods, plus each stock's all-time average, as of Apr 1, 2026.


SymbolName1Y Sortino Ratio5Y Sortino Ratio10Y Sortino RatioAll Time Sortino Ratio
EGRXEagle Pharmaceuticals Inc11.13
RGCRegencell Bioscience Holdings Limited6.67
INDVIndivior PLC Ordinary Shares6.06
BIOABioAge Labs, Inc4.80
PAHCPhibro Animal Health Corporation3.96
IXHLIncannex Healthcare Ltd ADR3.95
SDZNYSandoz Group AG3.69
ELANElanco Animal Health Incorporated3.65
TEVATeva Pharmaceutical Industries Limited3.07
AYTUAytu BioPharma, Inc.3.01
PRFXPainReform Ltd.-1.58

S&P 500 Index

How to choose period

Historical Sortino Ratio

The chart shows PRFX's rolling Sortino ratio over time compared to your chosen benchmark. Rising trends indicate improving returns relative to downside risk, while declining trends may signal deteriorating risk-adjusted performance or increased volatility during market stress. Use multiple timeframes to distinguish short-term fluctuations from long-term patterns.

Identify market cycles by observing when PRFX consistently outperforms (line above benchmark), underperforms (below benchmark), or aligns with the benchmark.


Loading graphics...

Explore PRFX risk-adjusted metrics in detail

Dive deeper into individual metrics with historical trends, benchmark comparisons, and performance across different time periods.