- ISIN
- US63909J1088
- CUSIP
- 63909J108
- Sector
- Healthcare
- Industry
- Biotechnology
- IPO Date
- Jun 10, 2021
Highlights
- Market Cap
- $124.33M
- Enterprise Value
- $142.97M
- EPS (TTM)
- -$0.45
- Total Revenue (TTM)
- $190.00K
- Gross Profit (TTM)
- -$3.03M
- EBITDA (TTM)
- -$53.13M
- Year Range
- $0.62 - $4.31
- Target Price
- $2.50
- ROA (TTM)
- -34.55%
- ROE (TTM)
- -43.11%
- Avg. Volume (1M)
- 913K
- Avg. Volume Value (1M)
- $1.42M
Share Price Chart
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Performance
NAUT Performance Chart
Nautilus Biotechnology, Inc. (NAUT) is down 49.9% since the beginning of the year. At $1 per share, NAUT is trading 77.3% below its 52-week high of $4. Investors who bought $1,000 worth of NAUT shares 5 years ago would now be looking at an investment worth $125.
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Returns By Period
Nautilus Biotechnology, Inc. (NAUT) has returned -49.90% so far this year and 27.83% over the past 12 months.
Nautilus Biotechnology, Inc.
- 1D
- -5.15%
- 1M
- -43.53%
- 6M
- -49.90%
- YTD
- -49.90%
- 1Y
- 27.83%
- 3Y*
- -32.31%
- 5Y*
- -34.07%
- 10Y*
- —
- ALL TIME*
- -38.10%
Benchmark (S&P 500 Index)
- 1D
- 0.70%
- 1M
- 0.09%
- 6M
- 7.94%
- YTD
- 9.41%
- 1Y
- 20.07%
- 3Y*
- 17.84%
- 5Y*
- 11.25%
- 10Y*
- 13.26%
- ALL TIME*
- 8.09%
NAUT Monthly Returns History
Based on dividend-adjusted daily data since Jun 10, 2021, NAUT's average daily return is -0.06%, while the average monthly return is -1.62%.
Historically, 44% of months were positive and 56% were negative. The best month was Nov 2025 with a return of +69.2%, while the worst month was Jul 2026 at -47.8%. The longest winning streak lasted 3 consecutive months, and the longest losing streak was 4 months.
On a daily basis, NAUT closed higher 45% of trading days. The best single day was Nov 3, 2025 with a return of +39.1%, while the worst single day was Jul 28, 2026 at -27.7%.
| Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec | Total | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026 | -0.00% | 24.10% | 60.33% | -32.22% | 4.18% | -31.75% | -47.75% | -49.90% | |||||
| 2025 | 1.79% | -23.98% | -33.77% | -20.02% | 8.48% | -2.96% | 4.84% | -10.53% | 24.25% | 57.42% | 69.17% | -13.33% | 16.07% |
| 2024 | -7.02% | -3.24% | 9.29% | -13.61% | 7.87% | -14.60% | 15.81% | -4.06% | 9.62% | -8.77% | -13.85% | -25.00% | -43.81% |
| 2023 | 8.89% | 8.16% | 30.66% | -6.86% | 10.85% | 35.31% | -14.99% | -1.82% | -2.17% | -18.99% | 7.42% | 8.73% | 66.11% |
| 2022 | -24.32% | 2.04% | 8.50% | 7.60% | -21.63% | -26.50% | 8.18% | -24.05% | -4.07% | 16.51% | -26.72% | -0.55% | -65.25% |
| 2021 | -12.10% | -22.38% | 0.64% | -22.18% | -13.03% | -9.18% | 6.80% | -54.92% |
Benchmark Metrics
Nautilus Biotechnology, Inc. has an annualized alpha of -30.60%, beta of 1.60, and R2 of 0.11 versus S&P 500 Index. Calculated based on daily prices since June 10, 2021.
- This stock participated in 227.04% of S&P 500 Index downside but only 49.01% of its upside - more exposed to losses than it benefited from rallies.
- R2 of 0.11 means this stock moves largely independently of S&P 500 Index - capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.
- Alpha
- -30.60%
- Beta
- 1.60
- R²
- 0.11
- Upside Capture
- 49.01%
- Downside Capture
- 227.04%
Return for Risk
Risk / Return Rank
NAUT ranks 58 for risk / return — above 58% of stocks peers on PortfoliosLab. Its historical combined result is near the middle of the peer group.
Risk / Return Metrics
The table below present risk-adjusted performance metrics for Nautilus Biotechnology, Inc. (NAUT) and compare them to S&P 500 Index.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| NAUT | Benchmark | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -1.15 | ||
| Sortino ratioReturn per unit of downside risk | -0.74 | ||
| Omega ratioGain probability vs. loss probability | 1.15 | 1.25 | -0.10 |
| Calmar ratioReturn relative to maximum drawdown | 0.38 | 2.00 | -1.62 |
| Martin ratioReturn relative to average drawdown | 1.08 | 8.49 | -7.41 |
Dividends
Dividend History
Drawdowns
Drawdowns Chart
The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.
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Worst Drawdowns
The table below displays the maximum drawdowns of the Nautilus Biotechnology, Inc.. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.
The maximum drawdown for the Nautilus Biotechnology, Inc. was 94.44%, occurring on Sep 3, 2025. The portfolio has not yet recovered.
The current Nautilus Biotechnology, Inc. drawdown is 91.50%.
Drawdown | Fall | Recovery | Underwater | Related event |
|---|---|---|---|---|
-94.44%Sep 2025 | 4y 2mo | — | 5y 1moJun 2021 - now | — |
Drawdown Indicators
| NAUT | Benchmark | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -94.44% | -56.78% | -37.66% |
Max Drawdown (1Y)Largest decline over 1 year | -75.27% | -9.10% | -66.17% |
Max Drawdown (3Y)Largest decline over 3 years | -83.78% | -18.90% | -64.88% |
Max Drawdown (5Y)Largest decline over 5 years | -92.25% | -25.43% | -66.82% |
Max Drawdown (10Y)Largest decline over 10 years | — | -33.92% | — |
Current DrawdownCurrent decline from peak | -91.50% | -1.58% | -89.92% |
Average DrawdownAverage peak-to-trough decline | -74.68% | -10.70% | -63.98% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 26.48% | 2.14% | +24.34% |
Volatility
Volatility Chart
The chart below shows the rolling one-month volatility.
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Financials
Financial Performance
The chart below illustrates the trends in the financial health of Nautilus Biotechnology, Inc. over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.
Valuation
The Valuation section provides an overview of how Nautilus Biotechnology, Inc. is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.
PS Ratio
This chart shows the Price-to-Sales (P/S) ratio for NAUT relative to other companies in the Biotechnology industry. Currently, NAUT has a P/S ratio of 650.6. This P/S ratio is high relative to other companies in the industry. It could mean the stock is overvalued, or that investors expect strong future growth and profitability.
PB Ratio
The chart illustrates the Price-to-Book (P/B) ratio for NAUT in comparison with other companies in the Biotechnology industry. Currently, NAUT has a P/B value of 0.9. This P/B ratio is low compared to industry peers. It might indicate the stock is undervalued or that the company’s assets are not expected to generate strong returns.
Income Statement
| TTM | |
|---|---|
Revenue | |
Total Revenue | — |
Cost Of Revenue | — |
Gross Profit | — |
Operating Expenses | |
Selling, General & Admin Expenses | — |
R&D Expenses | — |
Depreciation And Amortization | — |
Total Operating Expenses | — |
Income | |
Income Before Tax | — |
Operating Income | — |
EBITDA | — |
EBIT | — |
Earnings From Continuing Operations | — |
Net Income | — |
Income Tax Expense | — |
Other Non-Operating Income (Expenses) | — |
Extraordinary Items | — |
Discontinued Operations | — |
Effect Of Accounting Charges | — |
Non Recurring | — |
Minority Interest | — |
Other Items | — |
Interest Income | — |
Interest Expense | — |
Net Interest Income | — |
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