- ISIN
- US63909J1088
- CUSIP
- 63909J108
- Sector
- Healthcare
- Industry
- Biotechnology
- IPO Date
- Jun 10, 2021
Highlights
- Market Cap
- $326.72M
- Enterprise Value
- $344.82M
- EPS (TTM)
- -$0.45
- Gross Profit (TTM)
- -$4.84M
- EBITDA (TTM)
- -$37.55M
- Year Range
- $0.62 - $4.31
- Target Price
- $2.50
- ROA (TTM)
- -32.11%
- ROE (TTM)
- -39.53%
Share Price Chart
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Performance
NAUT Performance Chart
Nautilus Biotechnology, Inc. (NAUT) is up 32.3% since the beginning of the year. At $3 per share, NAUT is trading 40.1% below its 52-week high of $4.
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Returns By Period
Nautilus Biotechnology, Inc. (NAUT) has returned 32.31% so far this year and 236.03% over the past 12 months.
Nautilus Biotechnology, Inc.
- 1D
- -3.73%
- 1M
- -10.73%
- YTD
- 32.31%
- 6M
- 24.04%
- 1Y
- 236.03%
- 3Y*
- -2.46%
- 5Y*
- —
- 10Y*
- —
Benchmark (S&P 500 Index)
- 1D
- -0.74%
- 1M
- 4.90%
- YTD
- 10.35%
- 6M
- 10.28%
- 1Y
- 26.52%
- 3Y*
- 20.83%
- 5Y*
- 12.30%
- 10Y*
- 13.66%
NAUT Monthly Returns History
Based on dividend-adjusted daily data since Jun 10, 2021, NAUT's average daily return is +0.01%, while the average monthly return is -0.38%.
Historically, 46% of months were positive and 54% were negative. The best month was Nov 2025 with a return of +69.2%, while the worst month was Mar 2025 at -33.8%. The longest winning streak lasted 3 consecutive months, and the longest losing streak was 4 months.
On a daily basis, NAUT closed higher 46% of trading days. The best single day was Nov 3, 2025 with a return of +39.1%, while the worst single day was Mar 11, 2024 at -19.1%.
| Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec | Total | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026 | 0.00% | 24.10% | 60.33% | -32.22% | 4.18% | -5.84% | 32.31% | ||||||
| 2025 | 1.79% | -23.98% | -33.77% | -20.02% | 8.48% | -2.96% | 4.84% | -10.53% | 24.25% | 57.42% | 69.17% | -13.33% | 16.07% |
| 2024 | -7.02% | -3.24% | 9.29% | -13.61% | 7.87% | -14.60% | 15.81% | -4.06% | 9.62% | -8.77% | -13.85% | -25.00% | -43.81% |
| 2023 | 8.89% | 8.16% | 30.66% | -6.86% | 10.85% | 35.31% | -14.99% | -1.82% | -2.17% | -18.99% | 7.42% | 8.73% | 66.11% |
| 2022 | -24.32% | 2.04% | 8.50% | 7.60% | -21.63% | -26.50% | 8.18% | -24.05% | -4.07% | 16.51% | -26.72% | -0.55% | -65.25% |
| 2021 | -8.18% | -22.38% | 0.64% | -22.18% | -13.03% | -9.18% | 6.80% | -52.91% |
Benchmark Metrics
Nautilus Biotechnology, Inc. has an annualized alpha of -17.64%, beta of 1.61, and R2 of 0.12 versus S&P 500 Index. Calculated based on daily prices since June 11, 2021.
- This stock participated in 191.69% of S&P 500 Index downside but only 52.29% of its upside - more exposed to losses than it benefited from rallies.
- R2 of 0.12 means this stock moves largely independently of S&P 500 Index - capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.
- Alpha
- -17.64%
- Beta
- 1.61
- R²
- 0.12
- Upside Capture
- 52.29%
- Downside Capture
- 191.69%
Return for Risk
Risk / Return Rank
NAUT ranks 90 for risk / return — in the top 90% of stocks on our site. This means strong returns relative to risk — exactly what professional investors look for. Well-suited for investors who want to maximize return per unit of risk.
Return / Risk — by metrics
The table below present risk-adjusted performance metrics for Nautilus Biotechnology, Inc. (NAUT) and compare them to S&P 500 Index.
| NAUT | Benchmark | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +0.05 | ||
| Sortino ratioReturn per unit of downside risk | -0.08 | ||
| Omega ratioGain probability vs. loss probability | 1.37 | 1.41 | -0.04 |
| Calmar ratioReturn relative to maximum drawdown | 5.90 | 2.93 | +2.98 |
| Martin ratioReturn relative to average drawdown | 14.18 | 13.52 | +0.66 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
Dividends
Dividend History
Drawdowns
Drawdowns Chart
The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.
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Worst Drawdowns
The table below displays the maximum drawdowns of the Nautilus Biotechnology, Inc.. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.
The maximum drawdown for the Nautilus Biotechnology, Inc. was 94.19%, occurring on Sep 3, 2025. The portfolio has not yet recovered.
The current Nautilus Biotechnology, Inc. drawdown is 76.55%.
Related event | Drawdown | Fall | Recovery | Underwater |
|---|---|---|---|---|
2025 bear market2025 | -94.19%Sep 2025 | 4y 2mo | — | 4y 11moJun 2021 - now |
Drawdown Indicators
| NAUT | Benchmark | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -94.19% | -56.78% | -37.41% |
Max Drawdown (1Y)Largest decline over 1 year | -40.25% | -9.10% | -31.15% |
Max Drawdown (3Y)Largest decline over 3 years | -85.86% | -18.90% | -66.96% |
Max Drawdown (5Y)Largest decline over 5 years | — | -25.43% | — |
Max Drawdown (10Y)Largest decline over 10 years | — | -33.92% | — |
Current DrawdownCurrent decline from peak | -76.55% | -0.74% | -75.81% |
Average DrawdownAverage peak-to-trough decline | -73.32% | -10.72% | -62.60% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 16.73% | 1.97% | +14.76% |
Volatility
Volatility Chart
The chart below shows the rolling one-month volatility.
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Financials
Financial Performance
The chart below illustrates the trends in the financial health of Nautilus Biotechnology, Inc. over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.
Valuation
The Valuation section provides an overview of how Nautilus Biotechnology, Inc. is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.
PB Ratio
The chart illustrates the Price-to-Book (P/B) ratio for NAUT in comparison with other companies in the Biotechnology industry. Currently, NAUT has a P/B value of 2.3. This P/B ratio is in line with the industry average, suggesting the stock is valued fairly in relation to its book value.
Income Statement
| TTM | |
|---|---|
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Total Revenue | — |
Cost Of Revenue | — |
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Income | — |
Income Before Tax | — |
Operating Income | — |
EBITDA | — |
EBIT | — |
Earnings From Continuing Operations | — |
Net Income | — |
Income Tax Expense | — |
Other Non-Operating Income (Expenses) | — |
Extraordinary Items | — |
Discontinued Operations | — |
Effect Of Accounting Charges | — |
Non Recurring | — |
Minority Interest | — |
Other Items | — |
Interest Income | — |
Interest Expense | — |
Net Interest Income | — |
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