JNGLX vs. VOO
Compare and contrast key facts about Janus Henderson Global Life Sciences Fund (JNGLX) and Vanguard S&P 500 ETF (VOO).
JNGLX is managed by Janus Henderson. It was launched on Dec 30, 1998. VOO is a passively managed fund by Vanguard that tracks the performance of the S&P 500 Index. It was launched on Sep 7, 2010.
Performance
JNGLX vs. VOO - Performance Comparison
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JNGLX vs. VOO - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
JNGLX Janus Henderson Global Life Sciences Fund | -3.73% | 24.84% | 3.60% | 7.51% | -2.69% | 6.78% | 25.66% | 29.20% | 4.17% | 22.13% |
VOO Vanguard S&P 500 ETF | -3.66% | 17.82% | 24.98% | 26.32% | -18.17% | 28.79% | 18.32% | 31.37% | -4.50% | 21.77% |
Returns By Period
The year-to-date returns for both investments are quite close, with JNGLX having a -3.73% return and VOO slightly higher at -3.66%. Over the past 10 years, JNGLX has underperformed VOO with an annualized return of 11.02%, while VOO has yielded a comparatively higher 14.14% annualized return.
JNGLX
- 1D
- 3.08%
- 1M
- -5.55%
- YTD
- -3.73%
- 6M
- 11.88%
- 1Y
- 21.71%
- 3Y*
- 10.69%
- 5Y*
- 7.33%
- 10Y*
- 11.02%
VOO
- 1D
- 0.79%
- 1M
- -4.29%
- YTD
- -3.66%
- 6M
- -1.41%
- 1Y
- 18.17%
- 3Y*
- 18.58%
- 5Y*
- 11.93%
- 10Y*
- 14.14%
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JNGLX vs. VOO - Expense Ratio Comparison
JNGLX has a 0.80% expense ratio, which is higher than VOO's 0.03% expense ratio.
Return for Risk
JNGLX vs. VOO — Risk / Return Rank
JNGLX
VOO
JNGLX vs. VOO - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Janus Henderson Global Life Sciences Fund (JNGLX) and Vanguard S&P 500 ETF (VOO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| JNGLX | VOO | Difference | |
|---|---|---|---|
Sharpe ratioReturn per unit of total volatility | 1.07 | 1.01 | +0.06 |
Sortino ratioReturn per unit of downside risk | 1.54 | 1.53 | +0.01 |
Omega ratioGain probability vs. loss probability | 1.20 | 1.23 | -0.03 |
Calmar ratioReturn relative to maximum drawdown | 1.80 | 1.55 | +0.25 |
Martin ratioReturn relative to average drawdown | 4.97 | 7.31 | -2.34 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| JNGLX | VOO | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 1.07 | 1.01 | +0.06 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | 0.47 | 0.71 | -0.24 |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | 0.63 | 0.79 | -0.15 |
Sharpe Ratio (All Time)Calculated using the full available price history | 0.57 | 0.83 | -0.26 |
Correlation
The correlation between JNGLX and VOO is 0.72, which is considered to be high. That indicates a strong positive relationship between their price movements. Having highly-correlated positions in a portfolio may signal a lack of diversification, potentially leading to increased risk during market downturns.
Dividends
JNGLX vs. VOO - Dividend Comparison
JNGLX's dividend yield for the trailing twelve months is around 4.74%, more than VOO's 1.18% yield.
| TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
JNGLX Janus Henderson Global Life Sciences Fund | 4.74% | 4.56% | 5.84% | 4.26% | 0.25% | 9.85% | 7.80% | 6.23% | 13.32% | 0.89% | 0.30% | 8.81% |
VOO Vanguard S&P 500 ETF | 1.18% | 1.13% | 1.24% | 1.46% | 1.69% | 1.25% | 1.54% | 1.88% | 2.06% | 1.78% | 2.02% | 2.10% |
Drawdowns
JNGLX vs. VOO - Drawdown Comparison
The maximum JNGLX drawdown since its inception was -59.00%, which is greater than VOO's maximum drawdown of -33.99%. Use the drawdown chart below to compare losses from any high point for JNGLX and VOO.
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Drawdown Indicators
| JNGLX | VOO | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -59.00% | -33.99% | -25.01% |
Max Drawdown (1Y)Largest decline over 1 year | -9.68% | -11.98% | +2.30% |
Max Drawdown (5Y)Largest decline over 5 years | -22.21% | -24.52% | +2.31% |
Max Drawdown (10Y)Largest decline over 10 years | -27.37% | -33.99% | +6.62% |
Current DrawdownCurrent decline from peak | -6.62% | -5.55% | -1.07% |
Average DrawdownAverage peak-to-trough decline | -17.73% | -3.72% | -14.01% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 3.61% | 2.55% | +1.06% |
Volatility
JNGLX vs. VOO - Volatility Comparison
Janus Henderson Global Life Sciences Fund (JNGLX) has a higher volatility of 5.98% compared to Vanguard S&P 500 ETF (VOO) at 5.34%. This indicates that JNGLX's price experiences larger fluctuations and is considered to be riskier than VOO based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| JNGLX | VOO | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 5.98% | 5.34% | +0.64% |
Volatility (6M)Calculated over the trailing 6-month period | 10.63% | 9.47% | +1.16% |
Volatility (1Y)Calculated over the trailing 1-year period | 17.86% | 18.11% | -0.25% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 15.69% | 16.82% | -1.13% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 17.42% | 17.99% | -0.57% |