- ISIN
- US4037831033
- Sector
- Healthcare
- Industry
- Biotechnology
- IPO Date
- Apr 12, 2006
Highlights
- Market Cap
- $519.75M
- Enterprise Value
- $483.82M
- EPS (TTM)
- -$0.02
- Total Revenue (TTM)
- $117.05M
- Gross Profit (TTM)
- $111.30M
- EBITDA (TTM)
- $2.55M
- Year Range
- $5.44 - $9.42
- Target Price
- $17.00
- ROA (TTM)
- -3.88%
- ROE (TTM)
- -6.21%
Share Price Chart
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Performance
GYRE Performance Chart
Gyre Therapeutics Inc (GYRE) is down 19.4% since the beginning of the year. At $6 per share, GYRE is trading 39.6% below its 52-week high of $9. Investors who bought $1,000 worth of GYRE shares 5 years ago would now be looking at an investment worth $555.
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Returns By Period
Gyre Therapeutics Inc (GYRE) has returned -19.41% so far this year and -30.78% over the past 12 months. Over the last ten years, GYRE has returned -20.75% per year, falling short of the S&P 500 Index benchmark, which averaged 13.66% annually.
Gyre Therapeutics Inc
- 1D
- 2.34%
- 1M
- -28.16%
- YTD
- -19.41%
- 6M
- -25.52%
- 1Y
- -30.78%
- 3Y*
- 17.98%
- 5Y*
- -11.11%
- 10Y*
- -20.75%
Benchmark (S&P 500 Index)
- 1D
- -0.74%
- 1M
- 4.90%
- YTD
- 10.35%
- 6M
- 10.28%
- 1Y
- 26.52%
- 3Y*
- 20.83%
- 5Y*
- 12.30%
- 10Y*
- 13.66%
GYRE Monthly Returns History
Based on dividend-adjusted daily data since Apr 12, 2006, GYRE's average daily return is +0.11%, while the average monthly return is +1.61%. At this rate, an investment would double in approximately 3.6 years.
Historically, 45% of months were positive and 55% were negative. The best month was Jul 2009 with a return of +338.0%, while the worst month was Nov 2021 at -63.5%. The longest winning streak lasted 5 consecutive months, and the longest losing streak was 7 months.
On a daily basis, GYRE closed higher 47% of trading days. The best single day was May 23, 2022 with a return of +234.2%, while the worst single day was Jun 18, 2018 at -63.9%.
| Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec | Total | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026 | 14.59% | 1.85% | -15.41% | 10.19% | -23.05% | -3.72% | -19.41% | ||||||
| 2025 | -4.88% | 0.78% | -33.45% | 26.42% | -7.07% | -18.96% | -4.08% | 9.79% | -3.62% | 3.89% | -0.00% | -8.90% | -41.65% |
| 2024 | -51.85% | 46.65% | -3.64% | -10.76% | -27.18% | 5.02% | 21.29% | -4.84% | -8.93% | 14.04% | -12.52% | -3.28% | -52.90% |
| 2023 | -13.80% | 5.51% | -30.30% | 2.42% | 3.77% | 59.82% | 7.79% | 47.68% | -13.83% | -6.97% | 249.48% | 9.23% | 424.48% |
| 2022 | -36.54% | 11.90% | 1.69% | -27.42% | 158.87% | 43.55% | -1.69% | 12.57% | -2.68% | 7.16% | 3.24% | -5.40% | 119.54% |
| 2021 | -10.46% | 6.73% | -16.42% | 0.00% | -15.28% | 1.41% | -6.00% | 12.53% | -10.26% | -19.95% | -63.53% | -23.83% | -85.52% |
Benchmark Metrics
Gyre Therapeutics Inc has an annualized alpha of 12.16%, beta of 1.46, and R2 of 0.06 versus S&P 500 Index. Calculated based on daily prices since April 13, 2006.
- This stock participated in 196.46% of S&P 500 Index downside but only 70.15% of its upside - more exposed to losses than it benefited from rallies.
- R2 of 0.06 means this stock moves largely independently of S&P 500 Index - capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.
- Alpha
- 12.16%
- Beta
- 1.46
- R²
- 0.06
- Upside Capture
- 70.15%
- Downside Capture
- 196.46%
Return for Risk
Risk / Return Rank
GYRE ranks 15 for risk / return — in the bottom 15% of stocks on our site. This means you're taking on significantly more risk than the returns justify. Consider whether the potential upside is worth the volatility, or explore alternatives with better risk / return profiles.
Return / Risk — by metrics
The table below present risk-adjusted performance metrics for Gyre Therapeutics Inc (GYRE) and compare them to S&P 500 Index.
| GYRE | Benchmark | Difference | |
|---|---|---|---|
Sharpe ratioReturn per unit of total volatility | -0.52 | 2.24 | -2.76 |
Sortino ratioReturn per unit of downside risk | -0.47 | 3.07 | -3.55 |
Omega ratioGain probability vs. loss probability | 0.95 | 1.41 | -0.46 |
Calmar ratioReturn relative to maximum drawdown | -0.81 | 2.93 | -3.74 |
Martin ratioReturn relative to average drawdown | -1.85 | 13.52 | -15.37 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
Dividends
Dividend History
Gyre Therapeutics Inc provided a 0.00% dividend yield over the last twelve months, with an annual payout of $0.00 per share.
| Period | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dividend | $0.00 | $0.00 | $0.00 | $3.60 | $21.45 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $896.49 |
Dividend yield | 0.00% | 0.00% | 0.00% | 14.01% | 271.09% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 127.30% |
Monthly Dividends
The table displays the monthly dividend distributions for Gyre Therapeutics Inc. The dividends shown in the table have been adjusted to account for any splits that may have occurred.
| Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec | Total | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | ||||||
| 2025 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 |
| 2024 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 |
| 2023 | $3.60 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $3.60 |
| 2022 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $21.45 | $0.00 | $0.00 | $0.00 | $21.45 |
| 2021 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 |
Drawdowns
Drawdowns Chart
The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.
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Worst Drawdowns
The table below displays the maximum drawdowns of the Gyre Therapeutics Inc. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.
The maximum drawdown for the Gyre Therapeutics Inc was 99.98%, occurring on May 13, 2022. The portfolio has not yet recovered.
The current Gyre Therapeutics Inc drawdown is 99.90%.
Related event | Drawdown | Fall | Recovery | Underwater |
|---|---|---|---|---|
Bear market2022 | -99.98%May 2022 | 11y 2mo | — | 15y 3moMar 2011 - now |
Financial crisis2007–2009 | -84.89%Dec 2008 | 1y 4mo | 7mo 29d | 1y 12moJul 2007 - Jul 2009 |
2006 bear market2006 | -38.22%Sep 2006 | 5mo 5d | 3mo 13d | 8mo 18dApr 2006 - Dec 2006 |
2010 bear market2010 | -25.89%Aug 2010 | 3mo 24d | 2mo | 5mo 24dMay 2010 - Oct 2010 |
2010 bear market2010 | -21.70%Mar 2010 | 3mo 10d | 1mo 12d | 4mo 22dDec 2009 - Apr 2010 |
Drawdown Indicators
| GYRE | Benchmark | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -99.98% | -56.78% | -43.20% |
Max Drawdown (1Y)Largest decline over 1 year | -38.22% | -9.10% | -29.12% |
Max Drawdown (3Y)Largest decline over 3 years | -81.27% | -18.90% | -62.37% |
Max Drawdown (5Y)Largest decline over 5 years | -93.05% | -25.43% | -67.62% |
Max Drawdown (10Y)Largest decline over 10 years | -98.99% | -33.92% | -65.07% |
Current DrawdownCurrent decline from peak | -99.90% | -0.74% | -99.16% |
Average DrawdownAverage peak-to-trough decline | -76.29% | -10.72% | -65.57% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 16.69% | 1.97% | +14.72% |
Volatility
Volatility Chart
The chart below shows the rolling one-month volatility.
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Financials
Financial Performance
The chart below illustrates the trends in the financial health of Gyre Therapeutics Inc over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.
Valuation
The Valuation section provides an overview of how Gyre Therapeutics Inc is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.
PS Ratio
This chart shows the Price-to-Sales (P/S) ratio for GYRE relative to other companies in the Biotechnology industry. Currently, GYRE has a P/S ratio of 14.7. This P/S ratio falls within the average range for the industry, suggesting the stock is fairly valued based on its revenue.
PB Ratio
The chart illustrates the Price-to-Book (P/B) ratio for GYRE in comparison with other companies in the Biotechnology industry. Currently, GYRE has a P/B value of 5.1. This P/B ratio is in line with the industry average, suggesting the stock is valued fairly in relation to its book value.
Income Statement
| TTM | |
|---|---|
Revenue | — |
Total Revenue | — |
Cost Of Revenue | — |
Gross Profit | — |
Operating Expenses | — |
Selling, General & Admin Expenses | — |
R&D Expenses | — |
Depreciation And Amortization | — |
Total Operating Expenses | — |
Income | — |
Income Before Tax | — |
Operating Income | — |
EBITDA | — |
EBIT | — |
Earnings From Continuing Operations | — |
Net Income | — |
Income Tax Expense | — |
Other Non-Operating Income (Expenses) | — |
Extraordinary Items | — |
Discontinued Operations | — |
Effect Of Accounting Charges | — |
Non Recurring | — |
Minority Interest | — |
Other Items | — |
Interest Income | — |
Interest Expense | — |
Net Interest Income | — |
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