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L&G Pharma Breakthrough UCITS ETF (ETLI.DE) Alternatives

ETF · Currency in EUR · Last updated Jun 26, 2026

ETLI.DE is a passive ETF by Legal & General tracking the investment results of the Solactive Pharma Breakthrough Value. ETLI.DE launched on Jan 18, 2018 and has a 0.49% expense ratio.

L&G Pharma Breakthrough UCITS ETF (ETLI.DE) belongs to the Health & Biotech Equities category. Below you'll find alternative ETFs from the same category, ranked by key criteria, plus funds that investors commonly compare with ETLI.DE. Use the tables to find lower-cost options, better risk-adjusted returns, or a closer substitute for your current allocation.

Cheapest Alternatives to ETLI.DE

ETLI.DE charges 0.49% annually. There are 24 ETFs in the Health & Biotech Equities category with lower expense ratios, going as low as 0.12%.

SymbolNameExpense RatioAUMInception
XUHC.DE
Xtrackers MSCI USA Health Care UCITS ETF 1D0.12%—Sep 2017ETLI.DE vs XUHC.DE
QDVG.DE
iShares S&P 500 Health Care Sector UCITS ETF (Acc)0.15%—Nov 2015ETLI.DE vs QDVG.DE
ZPDH.DE
SPDR S&P US Health Care Select Sector UCITS ETF0.15%—Jul 2015ETLI.DE vs ZPDH.DE
DXSE.DE
Xtrackers MSCI Europe Health Care ESG Screened UCI...0.17%—Jun 2007ETLI.DE vs DXSE.DE
WELS.DE
Amundi S&P Global Health Care ESG UCITS ETF EUR Ac...0.18%—Sep 2022ETLI.DE vs WELS.DE

Best Risk-Adjusted Alternatives to ETLI.DE

ETLI.DE has a PortfoliosLab risk / return rank of 76. There are 4 ETFs in the Health & Biotech Equities category with higher risk-adjusted ranks, going as high as 92.

SymbolNameRisk / Return RankAUMInception
NBTK.DE
Invesco Nasdaq Biotech UCITS ETF
92
—Nov 2014ETLI.DE vs NBTK.DE
2B70.DE
iShares Nasdaq US Biotechnology UCITS ETF
92
—Oct 2017ETLI.DE vs 2B70.DE
GN0M.DE
Global X Genomics & Biotechnology UCITS ETF
80
—Nov 2021ETLI.DE vs GN0M.DE
2B77.DE
iShares Ageing Population UCITS ETF
77
—Sep 2016ETLI.DE vs 2B77.DE
WRNA.DE
WisdomTree BioRevolution UCITS ETF USD Acc
74
—Dec 2021ETLI.DE vs WRNA.DE

Top Performing ETLI.DE Alternatives (YTD)

ETLI.DE is at 9.42% YTD. There are 6 ETFs in the Health & Biotech Equities category with higher YTD returns, going as high as 25.35%.

SymbolNameYTD ReturnAUMInception
WELP.DE
HANetf HAN-GINS Indxx Healthcare Megatrend Equal W...
25.35%
—Sep 2022ETLI.DE vs WELP.DE
GN0M.DE
Global X Genomics & Biotechnology UCITS ETF
21.92%
—Nov 2021ETLI.DE vs GN0M.DE
WRNA.DE
WisdomTree BioRevolution UCITS ETF USD Acc
19.25%
—Dec 2021ETLI.DE vs WRNA.DE
2B70.DE
iShares Nasdaq US Biotechnology UCITS ETF
14.41%
—Oct 2017ETLI.DE vs 2B70.DE
NBTK.DE
Invesco Nasdaq Biotech UCITS ETF
13.45%
—Nov 2014ETLI.DE vs NBTK.DE

Lowest Volatility Alternatives to ETLI.DE

ETLI.DE has 19.01% 1-year volatility. There are 20 ETFs in the Health & Biotech Equities category with lower 1-year volatility, going as low as 12.13%.

SymbolNameVolatility 1YAUMInception
2B77.DE
iShares Ageing Population UCITS ETF12.13%—Sep 2016ETLI.DE vs 2B77.DE
XDWH.DE
Xtrackers MSCI World Health Care UCITS ETF 1C14.03%—Mar 2016ETLI.DE vs XDWH.DE
LYPE.DE
Amundi MSCI World Health Care UCITS ETF EUR Acc14.20%—Aug 2010ETLI.DE vs LYPE.DE
CBUF.DE
iShares MSCI World Health Care Sector ESG UCITS ET...14.56%—Oct 2019ETLI.DE vs CBUF.DE
WELG.DE
Amundi S&P Global Health Care ESG UCITS ETF EUR Di...14.82%—Sep 2022ETLI.DE vs WELG.DE

Lowest Drawdown Alternatives to ETLI.DE

ETLI.DE has a 1-year max drawdown of -9.04%. There are 3 ETFs in the Health & Biotech Equities category with shallower 1-year drawdowns, going as shallow as -6.24%.

SymbolNameMax Drawdown 1YAUMInception
NBTK.DE
Invesco Nasdaq Biotech UCITS ETF
-6.24%
—Nov 2014ETLI.DE vs NBTK.DE
2B70.DE
iShares Nasdaq US Biotechnology UCITS ETF
-6.28%
—Oct 2017ETLI.DE vs 2B70.DE
2B77.DE
iShares Ageing Population UCITS ETF
-6.76%
—Sep 2016ETLI.DE vs 2B77.DE
XDWH.DE
Xtrackers MSCI World Health Care UCITS ETF 1C
-9.82%
—Mar 2016ETLI.DE vs XDWH.DE
LYPE.DE
Amundi MSCI World Health Care UCITS ETF EUR Acc
-9.83%
—Aug 2010ETLI.DE vs LYPE.DE

Other ETFs from Legal & General

The 10 most viewed Legal & General ETFs shown here include LGGE.DE, XMLD.DE, USPY.DE and span 9 categories.

SymbolNameCategoryRisk / Return RankYTD ReturnAUMInception
LGGE.DE
L&G Quality Equity Dividends ESG Exclusions Europe...Europe Equities
85
12.88%
—Apr 2021ETLI.DE vs LGGE.DE
XMLD.DE
L&G Artificial Intelligence UCITS ETFTechnology Equities
77
37.67%
—Jun 2019ETLI.DE vs XMLD.DE
USPY.DE
L&G Cyber Security UCITS ETFTechnology Equities
31
34.15%
—Sep 2015ETLI.DE vs USPY.DE
RENW.DE
L&G Clean Energy UCITS ETFEnergy Equities
92
35.68%
—Nov 2020ETLI.DE vs RENW.DE
ETLX.DE
L&G Gold Mining UCITS ETFGold, Precious Metals
33
-11.01%
—Sep 2008ETLI.DE vs ETLX.DE
XMLC.DE
L&G Clean Water UCITS ETFWater Equities
27
8.02%
—Jun 2019ETLI.DE vs XMLC.DE
ETL2.DE
L&G Longer Dated All Commodities UCITS ETFCommodities
52
11.73%
—Mar 2010ETLI.DE vs ETL2.DE
IROB.DE
L&G ROBO Global Robotics and Automation UCITS ETFTechnology Equities
72
22.94%
—Oct 2014ETLI.DE vs IROB.DE
ETLK.DE
L&G Asia Pacific ex Japan Equity UCITS ETFAsia Pacific Equities
44
8.83%
—Oct 2018ETLI.DE vs ETLK.DE
ETLQ.DE
L&G Global Equity UCITS ETFGlobal Equities
79
10.95%
—Nov 2018ETLI.DE vs ETLQ.DE

Often Compared With ETLI.DE

Investors most often compare ETLI.DE with ESIH.DE, CIB0.DE, PPH. These 16 comparison targets span 4 categories, based on PortfoliosLab usage data.

SymbolNameCategoryRisk / Return RankYTD ReturnAUMInception
ESIH.DE
iShares MSCI Europe Health Care Sector UCITS ETF E...Health & Biotech Equities
26
2.95%
—Nov 2020ETLI.DE vs ESIH.DE
CIB0.DE
VanEck Bionic Engineering UCITS ETF AHealth & Biotech Equities
5
-11.68%
—Dec 2022ETLI.DE vs CIB0.DE
PPH
VanEck Pharmaceutical ETFHealth & Biotech Equities
46
4.38%
865.56MDec 2011ETLI.DE vs PPH
XDG3.DE
Xtrackers MSCI Global SDG 3 Good Health UCITS ETF ...Health & Biotech Equities
15
-2.12%
—Jan 2023ETLI.DE vs XDG3.DE
GLD
SPDR Gold SharesGold, Precious Metals
22
-6.77%
138.96BNov 2004ETLI.DE vs GLD
EHLT.DE
Lyxor STOXX Europe 600 Healthcare UCITS ETF DistHealth & Biotech Equities
26
2.61%
—Jul 2020ETLI.DE vs EHLT.DE
XGEN.DE
Xtrackers MSCI Genomic Healthcare Innovation UCITS...Health & Biotech Equities—
5.88%
—Jul 2022ETLI.DE vs XGEN.DE
SC0T.DE
Invesco European Health Care Sector UCITS ETFHealth & Biotech Equities
22
1.58%
—Jul 2009ETLI.DE vs SC0T.DE
DDOC.DE
Global X Telemedicine & Digital Health UCITS ETF A...Health & Biotech Equities
12
5.12%
—Dec 2020ETLI.DE vs DDOC.DE
2B78.DE
iShares Healthcare Innovation UCITS ETFHealth & Biotech Equities
52
6.74%
—Sep 2016ETLI.DE vs 2B78.DE
W311.DE
HANetf HAN-GINS Indxx Healthcare Megatrend Equal W...Health & Biotech Equities, Equal Weight
27
4.11%
—Apr 2019ETLI.DE vs W311.DE
WH2E.DE
Invesco S&P World Health Care ESG UCITS ETF AccHealth & Biotech Equities
29
-0.57%
—Apr 2023ETLI.DE vs WH2E.DE
LHTC.DE
Lyxor STOXX Europe 600 Healthcare UCITS ETF AccHealth & Biotech Equities
25
2.57%
—Aug 2006ETLI.DE vs LHTC.DE
SPYH.DE
State Street SPDR MSCI Europe Health Care UCITS ET...Health & Biotech Equities
28
3.28%
—Dec 2014ETLI.DE vs SPYH.DE
EXV4.DE
iShares STOXX Europe 600 Health Care UCITS ETF (DE...Health & Biotech Equities
25
2.38%
—Apr 2001ETLI.DE vs EXV4.DE
CURE.DE
VanEck Genomics and Healthcare Innovators UCITS ET...Health & Biotech Equities
20
0.01%
—Sep 2022ETLI.DE vs CURE.DE

Compare ETLI.DE with Any Fund or Stock

Compare ETLI.DE with any ETF, mutual fund, or stock using PortfoliosLab's comparison tool.

 

Diversifiers

Pair ETLI.DE with funds that move differently

L&G Pharma Breakthrough UCITS ETF alternatives help with substitution. Diversifiers are the next step when you want funds with lower historical correlation to ETLI.DE.

Explore ETLI.DE Diversifiers