XCUR vs. DRUG

Last updated Jun 4, 2026

XCUR (Exicure, Inc.) and DRUG (Bright Minds Biosciences Inc) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. Over the past 5 years, XCUR returned -58.30%/yr vs 26.80%/yr for DRUG. At a 0.04 correlation, their price movements are largely independent.

Performance

XCUR vs. DRUG - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Exicure, Inc. (XCUR) and Bright Minds Biosciences Inc (DRUG). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, XCUR achieves a -41.70% return, which is significantly lower than DRUG's -4.64% return.

XCUR

• 1D: 1.61%
• 1M: -2.77%
• YTD: -41.70%
• 6M: -43.17%
• 1Y: -69.53%
• 3Y*: -11.11%
• 5Y*: -58.30%
• 10Y*: —

DRUG

• 1D: -3.07%
• 1M: -10.62%
• YTD: -4.64%
• 6M: 0.49%
• 1Y: 171.01%
• 3Y*: 193.95%
• 5Y*: 26.80%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

XCUR vs. DRUG - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021
XCUR Exicure, Inc.	-41.70%	-60.35%	371.14%	-49.54%	-81.03%	-92.14%
DRUG Bright Minds Biosciences Inc	-4.64%	116.66%	2,418.88%	-61.35%	-76.66%	-41.30%

Correlation

The correlation between XCUR and DRUG is 0.09, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.09
Correlation (3Y) Calculated over the trailing 3-year period	0.03
Correlation (5Y) Calculated over the trailing 5-year period	0.04
Correlation (All Time) Calculated using the full available price history since Mar 23, 2021	0.04

Fundamentals

Market Cap XCUR : $20.14M DRUG : $713.68M
EPS XCUR : -$1.55 DRUG : -$3.48
PB Ratio XCUR : 9.60 DRUG : 2.31
Total Revenue (TTM) XCUR : $0.00 DRUG : $0.00
Gross Profit (TTM) XCUR : -$157.00K DRUG : -$20.13K
EBITDA (TTM) XCUR : -$8.38M DRUG : -$31.36M

Return for Risk

XCUR vs. DRUG — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

XCUR

XCUR Risk / Return Rank: 12
XCUR Sharpe Ratio Rank: 15
XCUR Sortino Ratio Rank: 15
XCUR Omega Ratio Rank: 16
XCUR Calmar Ratio Rank: 5
XCUR Martin Ratio Rank: 12

DRUG

DRUG Risk / Return Rank: 89
DRUG Sharpe Ratio Rank: 91
DRUG Sortino Ratio Rank: 88
DRUG Omega Ratio Rank: 84
DRUG Calmar Ratio Rank: 93
DRUG Martin Ratio Rank: 91

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

XCUR vs. DRUG - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Exicure, Inc. (XCUR) and Bright Minds Biosciences Inc (DRUG). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	XCUR	DRUG	Difference
Sharpe ratio Return per unit of total volatility	-0.62	2.39	-3.00
Sortino ratio Return per unit of downside risk	-0.78	3.06	-3.84
Omega ratio Gain probability vs. loss probability	0.91	1.34	-0.44
Calmar ratio Return relative to maximum drawdown	-0.93	6.00	-6.92
Martin ratio Return relative to average drawdown	-1.27	13.58	-14.85
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

XCUR vs. DRUG - Sharpe Ratio Comparison

The current XCUR Sharpe Ratio is -0.62, which is lower than the DRUG Sharpe Ratio of 2.39. The chart below compares the historical Sharpe Ratios of XCUR and DRUG, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	XCUR	DRUG	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.62	2.39	-3.00
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.39	0.04	-0.43
Sharpe Ratio (All Time) Calculated using the full available price history	-0.36	0.03	-0.39

Drawdowns

XCUR vs. DRUG - Drawdown Comparison

The maximum XCUR drawdown since its inception was -99.85%, roughly equal to the maximum DRUG drawdown of -97.68%. Use the drawdown chart below to compare losses from any high point for XCUR and DRUG.

Drawdown Indicators

	XCUR	DRUG	Difference
Max Drawdown Largest peak-to-trough decline	-99.85%	-97.68%	-2.17%
Max Drawdown (1Y) Largest decline over 1 year	-75.24%	-28.69%	-46.55%
Max Drawdown (3Y) Largest decline over 3 years	-91.64%	-76.98%	-14.66%
Max Drawdown (5Y) Largest decline over 5 years	-99.45%	-97.68%	-1.77%
Current Drawdown Current decline from peak	-99.68%	-22.47%	-77.21%
Average Drawdown Average peak-to-trough decline	-81.64%	-59.03%	-22.61%
Ulcer Index Depth and duration of drawdowns from previous peaks	54.93%	12.65%	+42.28%

Volatility

XCUR vs. DRUG - Volatility Comparison

Exicure, Inc. (XCUR) has a higher volatility of 23.97% compared to Bright Minds Biosciences Inc (DRUG) at 19.47%. This indicates that XCUR's price experiences larger fluctuations and is considered to be riskier than DRUG based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	XCUR	DRUG	Difference
Volatility (1M) Calculated over the trailing 1-month period	23.97%	19.47%	+4.50%
Volatility (6M) Calculated over the trailing 6-month period	78.47%	46.83%	+31.64%
Volatility (1Y) Calculated over the trailing 1-year period	113.10%	72.13%	+40.97%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	150.39%	662.71%	-512.32%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	130.64%	649.79%	-519.15%

Dividends

XCUR vs. DRUG - Dividend Comparison

Neither XCUR nor DRUG has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both XCUR and DRUG in my portfolio?

XCUR and DRUG have a correlation of 0.09, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, XCUR or DRUG?

XCUR has higher volatility (23.97%) compared to DRUG (19.47%). In terms of maximum drawdown, XCUR dropped -99.85% vs DRUG's -97.68%.

Which has better risk-adjusted returns?

DRUG currently has the higher Sharpe Ratio (2.39 vs -0.62), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.