UTHR vs. FFIV

Last updated Jun 13, 2026

UTHR (United Therapeutics Corporation) and FFIV (F5 Networks, Inc.) are both stocks. UTHR operates in Biotechnology (Healthcare), while FFIV operates in Software - Infrastructure (Technology). Over the past 10 years, UTHR returned 17.67%/yr vs 12.87%/yr for FFIV. At a 0.25 correlation, their price movements are largely independent.

Performance

UTHR vs. FFIV - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in United Therapeutics Corporation (UTHR) and F5 Networks, Inc. (FFIV). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, UTHR achieves a 12.05% return, which is significantly lower than FFIV's 55.20% return. Over the past 10 years, UTHR has outperformed FFIV with an annualized return of 17.67%, while FFIV has yielded a comparatively lower 12.87% annualized return.

UTHR

• 1D: 0.10%
• 1M: -5.79%
• YTD: 12.05%
• 6M: 10.52%
• 1Y: 90.80%
• 3Y*: 33.49%
• 5Y*: 24.97%
• 10Y*: 17.67%

FFIV

• 1D: 0.59%
• 1M: 10.84%
• YTD: 55.20%
• 6M: 50.82%
• 1Y: 35.83%
• 3Y*: 38.11%
• 5Y*: 15.50%
• 10Y*: 12.87%

*Multi-year figures are annualized to reflect compound growth (CAGR)

UTHR vs. FFIV - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
UTHR United Therapeutics Corporation	12.05%	38.09%	60.46%	-20.93%	28.70%	42.35%	72.33%	-19.12%	-26.39%	3.15%
FFIV F5 Networks, Inc.	55.20%	1.51%	40.50%	24.72%	-41.36%	39.09%	25.99%	-13.81%	23.48%	-9.33%

Correlation

The correlation between UTHR and FFIV is 0.01, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.01
Correlation (3Y) Calculated over the trailing 3-year period	0.11
Correlation (5Y) Calculated over the trailing 5-year period	0.17
Correlation (10Y) Calculated over the trailing 10-year period	0.23
Correlation (All Time) Calculated using the full available price history since Jun 17, 1999	0.25

Over the past year, the correlation between UTHR and FFIV has dropped to 0.01 - well below their long-term average of 0.25, suggesting their price drivers have been diverging.

Fundamentals

Market Cap UTHR : $25.77B FFIV : $22.70B
EPS UTHR : $27.00 FFIV : $12.19
PE Ratio UTHR : 20.22 FFIV : 32.50
PEG Ratio UTHR : 0.66 FFIV : 1.42
PS Ratio UTHR : 8.21 FFIV : 9.54
PB Ratio UTHR : 4.37 FFIV : 6.22
Total Revenue (TTM) UTHR : $3.17B FFIV : $2.41B
Gross Profit (TTM) UTHR : $2.74B FFIV : $2.63B
EBITDA (TTM) UTHR : $1.75B FFIV : $889.95M

Return for Risk

UTHR vs. FFIV — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

UTHR

UTHR Risk / Return Rank: 94
UTHR Sharpe Ratio Rank: 89
UTHR Sortino Ratio Rank: 96
UTHR Omega Ratio Rank: 94
UTHR Calmar Ratio Rank: 97
UTHR Martin Ratio Rank: 96

FFIV

FFIV Risk / Return Rank: 69
FFIV Sharpe Ratio Rank: 75
FFIV Sortino Ratio Rank: 69
FFIV Omega Ratio Rank: 70
FFIV Calmar Ratio Rank: 65
FFIV Martin Ratio Rank: 64

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

UTHR vs. FFIV - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for United Therapeutics Corporation (UTHR) and F5 Networks, Inc. (FFIV). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	UTHR	FFIV	Difference
Sharpe ratio: Return per unit of total volatility	1.92	1.08	+0.85
Sortino ratio: Return per unit of downside risk	4.23	1.58	+2.65
Omega ratio: Gain probability vs. loss probability	1.49	1.21	+0.28
Calmar ratio: Return relative to maximum drawdown	8.58	1.04	+7.54
Martin ratio: Return relative to average drawdown	20.13	2.28	+17.85

UTHR vs. FFIV - Sharpe Ratio Comparison

The current UTHR Sharpe Ratio is 1.92, which is higher than the FFIV Sharpe Ratio of 1.08. The chart below compares the historical Sharpe Ratios of UTHR and FFIV, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

UTHR vs. FFIV - Drawdown Comparison

The maximum UTHR drawdown since its inception was -93.18%, roughly equal to the maximum FFIV drawdown of -97.59%. Use the drawdown chart below to compare losses from any high point for UTHR and FFIV.

Drawdown Indicators

	UTHR	FFIV	Difference
Max Drawdown Largest peak-to-trough decline	-93.18%	-97.59%	+4.41%
Max Drawdown (1Y) Largest decline over 1 year	-10.64%	-34.73%	+24.09%
Max Drawdown (3Y) Largest decline over 3 years	-33.00%	-34.73%	+1.73%
Max Drawdown (5Y) Largest decline over 5 years	-33.00%	-47.42%	+14.42%
Max Drawdown (10Y) Largest decline over 10 years	-55.56%	-54.59%	-0.97%
Current Drawdown Current decline from peak	-8.51%	-3.17%	-5.34%
Average Drawdown Average peak-to-trough decline	-35.31%	-40.16%	+4.85%
Ulcer Index Depth and duration of drawdowns from previous peaks	4.53%	15.77%	-11.24%

Volatility

UTHR vs. FFIV - Volatility Comparison

The current volatility for United Therapeutics Corporation (UTHR) is 5.01%, while F5 Networks, Inc. (FFIV) has a volatility of 8.89%. This indicates that UTHR experiences smaller price fluctuations and is considered to be less risky than FFIV based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	UTHR	FFIV	Difference
Volatility (1M) Calculated over the trailing 1-month period	5.01%	8.89%	-3.88%
Volatility (6M) Calculated over the trailing 6-month period	25.94%	24.72%	+1.22%
Volatility (1Y) Calculated over the trailing 1-year period	47.55%	33.48%	+14.07%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	35.08%	29.97%	+5.11%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	35.06%	29.56%	+5.50%

Dividends

UTHR vs. FFIV - Dividend Comparison

Neither UTHR nor FFIV has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both UTHR and FFIV in my portfolio?

UTHR and FFIV have a correlation of 0.01, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, UTHR or FFIV?

FFIV has higher volatility (8.89%) compared to UTHR (5.01%). In terms of maximum drawdown, UTHR dropped -93.18% vs FFIV's -97.59%.

Which has better risk-adjusted returns?

UTHR currently has the higher Sharpe Ratio (1.92 vs 1.08), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.