TTMIX vs. THISX

Last updated Jun 3, 2026

TTMIX (T. Rowe Price Total Return Fund Class I) and THISX (T. Rowe Price Health Sciences Fund Class I) are both mutual funds - TTMIX is a Global Allocation fund managed by T. Rowe Price, while THISX is a Health & Biotech Equities fund actively managed by T. Rowe Price. Over the past 5 years, TTMIX returned 5.75%/yr vs 6.09%/yr for THISX. A 0.65 correlation means they provide meaningful diversification when combined. TTMIX charges 0.37%/yr vs 0.67%/yr for THISX.

Performance

TTMIX vs. THISX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in T. Rowe Price Total Return Fund Class I (TTMIX) and T. Rowe Price Health Sciences Fund Class I (THISX). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, TTMIX achieves a 4.51% return, which is significantly higher than THISX's -3.02% return.

TTMIX

• 1D: 0.68%
• 1M: 4.07%
• YTD: 4.51%
• 6M: 2.55%
• 1Y: 4.42%
• 3Y*: 21.34%
• 5Y*: 5.75%
• 10Y*: 14.91%

THISX

• 1D: -1.74%
• 1M: 2.22%
• YTD: -3.02%
• 6M: -2.49%
• 1Y: 20.81%
• 3Y*: 10.98%
• 5Y*: 6.09%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

TTMIX vs. THISX - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
TTMIX T. Rowe Price Total Return Fund Class I	4.51%	6.97%	38.33%	39.41%	-40.85%	9.92%	53.86%	35.84%	-1.73%	31.93%
THISX T. Rowe Price Health Sciences Fund Class I	-3.02%	17.92%	16.75%	3.17%	-12.11%	13.62%	30.35%	38.29%	1.20%	26.96%

Correlation

The correlation between TTMIX and THISX is 0.35, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.35
Correlation (3Y) Calculated over the trailing 3-year period	0.47
Correlation (5Y) Calculated over the trailing 5-year period	0.61
Correlation (All Time) Calculated using the full available price history since Jan 4, 2017	0.65

Over the past year, the correlation between TTMIX and THISX has dropped to 0.35 - well below their long-term average of 0.65, suggesting their price drivers have been diverging.

Return for Risk

TTMIX vs. THISX — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

TTMIX

TTMIX Risk / Return Rank: 4
TTMIX Sharpe Ratio Rank: 5
TTMIX Sortino Ratio Rank: 5
TTMIX Omega Ratio Rank: 5
TTMIX Calmar Ratio Rank: 4
TTMIX Martin Ratio Rank: 4

THISX

THISX Risk / Return Rank: 23
THISX Sharpe Ratio Rank: 26
THISX Sortino Ratio Rank: 27
THISX Omega Ratio Rank: 23
THISX Calmar Ratio Rank: 21
THISX Martin Ratio Rank: 18

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

TTMIX vs. THISX - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for T. Rowe Price Total Return Fund Class I (TTMIX) and T. Rowe Price Health Sciences Fund Class I (THISX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	TTMIX	THISX	Difference
Sharpe ratio Return per unit of total volatility	0.37	1.47	-1.10
Sortino ratio Return per unit of downside risk	0.62	2.18	-1.56
Omega ratio Gain probability vs. loss probability	1.07	1.25	-0.18
Calmar ratio Return relative to maximum drawdown	0.36	1.71	-1.36
Martin ratio Return relative to average drawdown	0.87	5.00	-4.13
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

TTMIX vs. THISX - Sharpe Ratio Comparison

The current TTMIX Sharpe Ratio is 0.37, which is lower than the THISX Sharpe Ratio of 1.47. The chart below compares the historical Sharpe Ratios of TTMIX and THISX, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	TTMIX	THISX	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	0.37	1.47	-1.10
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.27	0.33	-0.06
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.72	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	0.74	0.66	+0.08

Drawdowns

TTMIX vs. THISX - Drawdown Comparison

The maximum TTMIX drawdown since its inception was -47.11%, which is greater than THISX's maximum drawdown of -28.97%. Use the drawdown chart below to compare losses from any high point for TTMIX and THISX.

Drawdown Indicators

	TTMIX	THISX	Difference
Max Drawdown Largest peak-to-trough decline	-47.11%	-28.97%	-18.14%
Max Drawdown (1Y) Largest decline over 1 year	-17.25%	-12.78%	-4.47%
Max Drawdown (3Y) Largest decline over 3 years	-20.68%	-15.80%	-4.88%
Max Drawdown (5Y) Largest decline over 5 years	-47.11%	-27.53%	-19.58%
Max Drawdown (10Y) Largest decline over 10 years	-47.11%	—	—
Current Drawdown Current decline from peak	-3.71%	-6.07%	+2.36%
Average Drawdown Average peak-to-trough decline	-10.28%	-7.18%	-3.10%
Ulcer Index Depth and duration of drawdowns from previous peaks	7.16%	4.39%	+2.77%

Volatility

TTMIX vs. THISX - Volatility Comparison

The current volatility for T. Rowe Price Total Return Fund Class I (TTMIX) is 3.62%, while T. Rowe Price Health Sciences Fund Class I (THISX) has a volatility of 4.35%. This indicates that TTMIX experiences smaller price fluctuations and is considered to be less risky than THISX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	TTMIX	THISX	Difference
Volatility (1M) Calculated over the trailing 1-month period	3.62%	4.35%	-0.73%
Volatility (6M) Calculated over the trailing 6-month period	10.97%	11.77%	-0.80%
Volatility (1Y) Calculated over the trailing 1-year period	14.57%	15.32%	-0.75%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	21.21%	18.41%	+2.80%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	20.73%	19.96%	+0.77%

TTMIX vs. THISX - Expense Ratio Comparison

TTMIX has a 0.37% expense ratio, which is lower than THISX's 0.67% expense ratio.

Dividends

TTMIX vs. THISX - Dividend Comparison

TTMIX's dividend yield for the trailing twelve months is around 24.18%, more than THISX's 12.64% yield.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016
THISX T. Rowe Price Health Sciences Fund Class I	12.64%	12.25%	26.10%	5.20%	1.76%	7.62%	7.25%	12.58%	6.70%	7.55%	0.00%
TTMIX T. Rowe Price Total Return Fund Class I	24.18%	25.27%	7.45%	7.80%	17.43%	8.53%	5.27%	2.44%	1.41%	2.47%	2.23%

Frequently Asked Questions

Can I hold both TTMIX and THISX in my portfolio?

TTMIX and THISX have a correlation of 0.35, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, TTMIX or THISX?

THISX has higher volatility (4.35%) compared to TTMIX (3.62%). In terms of maximum drawdown, TTMIX dropped -47.11% vs THISX's -28.97%.

Which has better risk-adjusted returns?

THISX currently has the higher Sharpe Ratio (1.47 vs 0.37), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.