TPST vs. RPTX

Last updated Apr 1, 2026

Compare and contrast key facts about Tempest Therapeutics, Inc. (TPST) and Repare Therapeutics Inc. (RPTX).

Performance

TPST vs. RPTX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Tempest Therapeutics, Inc. (TPST) and Repare Therapeutics Inc. (RPTX). The values are adjusted to include any dividend payments, if applicable.

TPST vs. RPTX - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020
TPST Tempest Therapeutics, Inc.	-42.86%	-73.54%	-81.03%	282.61%	-78.22%	-83.55%	-22.18%
RPTX Repare Therapeutics Inc.	1.92%	98.47%	-82.05%	-50.37%	-30.25%	-38.51%	11.36%

Fundamentals

Market Cap TPST : $6.81M RPTX : $114.09M
EPS TPST : -$6.36 RPTX : -$1.68
PB Ratio TPST : 1.02 RPTX : 0.99
Total Revenue (TTM) TPST : $0.00 RPTX : $11.87M
Gross Profit (TTM) TPST : -$133.00K RPTX : $10.23M
EBITDA (TTM) TPST : -$10.27M RPTX : -$71.98M

Returns By Period

TPST

• 1D: 7.89%
• 1M: -26.13%
• YTD: -42.86%
• 6M: -83.84%
• 1Y: -82.35%
• 3Y*: -62.11%
• 5Y*: -63.34%
• 10Y*: -62.01%

RPTX

• 1D: —
• 1M: —
• YTD: —
• 6M: —
• 1Y: —
• 3Y*: —
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

TPST vs. RPTX — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

TPST

TPST Risk / Return Rank: 6
TPST Sharpe Ratio Rank: 9
TPST Sortino Ratio Rank: 7
TPST Omega Ratio Rank: 6
TPST Calmar Ratio Rank: 5
TPST Martin Ratio Rank: 5

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

TPST vs. RPTX - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Tempest Therapeutics, Inc. (TPST) and Repare Therapeutics Inc. (RPTX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	TPST	RPTX	Difference
Sharpe ratio Return per unit of total volatility	-0.80	—	—
Sortino ratio Return per unit of downside risk	-1.39	—	—
Omega ratio Gain probability vs. loss probability	0.80	—	—
Calmar ratio Return relative to maximum drawdown	-0.96	—	—
Martin ratio Return relative to average drawdown	-1.68	—	—
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

Sharpe Ratios by Period

	TPST	RPTX	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.80	—	—
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.04	—	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	-0.05	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.05	—	—

Correlation

The correlation between TPST and RPTX is 0.17, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

TPST vs. RPTX - Dividend Comparison

Neither TPST nor RPTX has paid dividends to shareholders.

Tickers have no history of dividend payments

Drawdowns

Drawdown Indicators

	TPST	RPTX	Difference
Max Drawdown Largest peak-to-trough decline	-100.00%	—	—
Max Drawdown (1Y) Largest decline over 1 year	-87.15%	—	—
Max Drawdown (5Y) Largest decline over 5 years	-99.52%	—	—
Max Drawdown (10Y) Largest decline over 10 years	-100.00%	—	—
Current Drawdown Current decline from peak	-100.00%	—	—
Average Drawdown Average peak-to-trough decline	-82.65%	—	—
Ulcer Index Depth and duration of drawdowns from previous peaks	49.91%	—	—

Volatility

Volatility by Period

	TPST	RPTX	Difference
Volatility (1M) Calculated over the trailing 1-month period	29.88%	—	—
Volatility (6M) Calculated over the trailing 6-month period	92.95%	—	—
Volatility (1Y) Calculated over the trailing 1-year period	103.55%	—	—
Volatility (5Y) Calculated over the trailing 5-year period, annualized	1,784.28%	—	—
Volatility (10Y) Calculated over the trailing 10-year period, annualized	1,262.43%	—	—

Financials