STRO vs. NVDA

Last updated Aug 1, 2026

STRO (Sutro Biopharma, Inc.) and NVDA (NVIDIA Corporation) are both stocks. STRO operates in Biotechnology (Healthcare), while NVDA operates in Semiconductors (Technology). Over the past 5 years, STRO returned -32.33%/yr vs 59.52%/yr for NVDA. Their 0.24 correlation means their historical movements had little consistent relationship.

Performance

STRO vs. NVDA - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Sutro Biopharma, Inc. (STRO) and NVIDIA Corporation (NVDA). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, STRO achieves a 108.90% return, which is significantly higher than NVDA's 7.77% return.

STRO

• 1D: -2.62%
• 1M: -20.57%
• 6M: 61.67%
• YTD: 108.90%
• 1Y: 198.40%
• 3Y*: -18.41%
• 5Y*: -32.33%
• 10Y*: —
• ALL TIME*: -20.85%

NVDA

• 1D: 2.93%
• 1M: 3.04%
• 6M: 5.16%
• YTD: 7.77%
• 1Y: 15.71%
• 3Y*: 62.93%
• 5Y*: 59.52%
• 10Y*: 64.62%
• ALL TIME*: 36.28%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison

Position	Avg. Volume Value (2W)	Avg. Volume Value (1M)	Avg. Volume Value (3M)
NVDA NVIDIA Corporation	$25.46B	$26.13B	$31.85B
STRO Sutro Biopharma, Inc.	$6.33M	$8.37M	$10.40M

STRO vs. NVDA - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018
STRO Sutro Biopharma, Inc.	108.90%	-37.12%	-57.11%	-46.91%	-45.70%	-31.46%	97.36%	21.95%	-40.34%
NVDA NVIDIA Corporation	7.77%	38.92%	171.25%	239.02%	-50.26%	125.48%	122.30%	76.94%	-49.93%

Correlation

The correlation between STRO and NVDA is 0.10, which is low. Their historical price movements had little consistent relationship.

	Correlation
Correlation (1Y) Focuses on recent behavior, but can change the most.	0.10
Correlation (3Y) Balances recent behavior with more history.	0.16
Correlation (5Y) Shows whether the relationship held over a longer period.	0.21
Correlation (All Time) Calculated using the full available price history since Sep 27, 2018	0.24

The correlation between STRO and NVDA shifts across timeframes, from 0.10 (1 year) to 0.24 (all time), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap STRO : $233.90M NVDA : $4.86T
EPS STRO : -$15.28 NVDA : $6.53
PS Ratio STRO : 2.44 NVDA : 19.35
Total Revenue (TTM) STRO : $99.61M NVDA : $253.49B
Gross Profit (TTM) STRO : $83.46M NVDA : $187.95B
EBITDA (TTM) STRO : -$105.17M NVDA : $192.76B

Return for Risk

STRO vs. NVDA — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

STRO

STRO Risk / Return Rank: 91
STRO Sharpe Ratio Rank: 94
STRO Sortino Ratio Rank: 89
STRO Omega Ratio Rank: 87
STRO Calmar Ratio Rank: 94
STRO Martin Ratio Rank: 91

NVDA

NVDA Risk / Return Rank: 56
NVDA Sharpe Ratio Rank: 58
NVDA Sortino Ratio Rank: 53
NVDA Omega Ratio Rank: 51
NVDA Calmar Ratio Rank: 60
NVDA Martin Ratio Rank: 59

The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

STRO vs. NVDA - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Sutro Biopharma, Inc. (STRO) and NVIDIA Corporation (NVDA). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	STRO	NVDA	Difference
Sharpe ratio: Return per unit of total volatility	2.24	0.36	+1.88
Sortino ratio: Return per unit of downside risk	2.71	0.76	+1.95
Omega ratio: Gain probability vs. loss probability	1.32	1.09	+0.24
Calmar ratio: Return relative to maximum drawdown	4.50	0.65	+3.85
Martin ratio: Return relative to average drawdown	10.46	1.32	+9.14

STRO vs. NVDA - Sharpe Ratio Comparison

The current STRO Sharpe Ratio is 2.24, which is higher than the NVDA Sharpe Ratio of 0.36. The chart below compares the historical Sharpe Ratios of STRO and NVDA, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

STRO vs. NVDA - Drawdown Comparison

The maximum STRO drawdown since its inception was -98.10%, which is greater than NVDA's maximum drawdown of -89.72%. Use the drawdown chart below to compare losses from any high point for STRO and NVDA.

Drawdown Indicators

	STRO	NVDA	Difference
Max Drawdown Largest peak-to-trough decline	-98.10%	-89.72%	-8.38%
Max Drawdown (1Y) Largest decline over 1 year	-44.78%	-20.21%	-24.57%
Max Drawdown (3Y) Largest decline over 3 years	-90.72%	-36.88%	-53.84%
Max Drawdown (5Y) Largest decline over 5 years	-97.77%	-66.34%	-31.43%
Max Drawdown (10Y) Largest decline over 10 years	—	-66.34%	—
Current Drawdown Current decline from peak	-91.22%	-14.74%	-76.48%
Average Drawdown Average peak-to-trough decline	-61.80%	-36.07%	-25.73%
Ulcer Index Depth and duration of drawdowns from previous peaks	19.22%	9.90%	+9.32%

Volatility

STRO vs. NVDA - Volatility Comparison

Sutro Biopharma, Inc. (STRO) has a higher volatility of 18.26% compared to NVIDIA Corporation (NVDA) at 12.04%. This indicates that STRO's price experiences larger fluctuations and is considered to be riskier than NVDA based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	STRO	NVDA	Difference
Volatility (1M) Calculated over the trailing 1-month period	18.26%	12.04%	+6.22%
Volatility (6M) Calculated over the trailing 6-month period	59.56%	28.30%	+31.26%
Volatility (1Y) Calculated over the trailing 1-year period	90.29%	36.41%	+53.88%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	88.71%	51.87%	+36.84%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	85.24%	49.95%	+35.29%

Dividends

STRO vs. NVDA - Dividend Comparison

STRO has not paid dividends to shareholders, while NVDA's dividend yield for the trailing twelve months is around 0.14%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
NVDA NVIDIA Corporation	0.14%	0.02%	0.03%	0.03%	0.11%	0.05%	0.12%	0.27%	0.46%	0.29%	0.45%	1.20%
STRO Sutro Biopharma, Inc.	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Financials

Frequently Asked Questions

Can I hold both STRO and NVDA in my portfolio?

STRO and NVDA have a correlation of 0.10, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, STRO or NVDA?

STRO has higher volatility (18.26%) compared to NVDA (12.04%). In terms of maximum drawdown, STRO dropped -98.10% vs NVDA's -89.72%.

Which has better risk-adjusted returns?

STRO currently has the higher Sharpe Ratio (2.24 vs 0.36), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.