RPTX vs. TPST

Last updated Apr 1, 2026

Compare and contrast key facts about Repare Therapeutics Inc. (RPTX) and Tempest Therapeutics, Inc. (TPST).

Performance

RPTX vs. TPST - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Repare Therapeutics Inc. (RPTX) and Tempest Therapeutics, Inc. (TPST). The values are adjusted to include any dividend payments, if applicable.

RPTX vs. TPST - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020
RPTX Repare Therapeutics Inc.	1.92%	98.47%	-82.05%	-50.37%	-30.25%	-38.51%	11.36%
TPST Tempest Therapeutics, Inc.	-42.86%	-73.54%	-81.03%	282.61%	-78.22%	-83.55%	-22.18%

Fundamentals

Market Cap RPTX : $114.09M TPST : $6.81M
EPS RPTX : -$1.68 TPST : -$6.36
PB Ratio RPTX : 0.99 TPST : 1.02
Total Revenue (TTM) RPTX : $11.87M TPST : $0.00
Gross Profit (TTM) RPTX : $10.23M TPST : -$133.00K
EBITDA (TTM) RPTX : -$71.98M TPST : -$10.27M

Returns By Period

RPTX

• 1D: —
• 1M: —
• YTD: —
• 6M: —
• 1Y: —
• 3Y*: —
• 5Y*: —
• 10Y*: —

TPST

• 1D: 7.89%
• 1M: -28.07%
• YTD: -42.86%
• 6M: -84.05%
• 1Y: -82.91%
• 3Y*: -62.11%
• 5Y*: -63.34%
• 10Y*: -62.01%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

RPTX vs. TPST — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

TPST

TPST Risk / Return Rank: 6
TPST Sharpe Ratio Rank: 9
TPST Sortino Ratio Rank: 7
TPST Omega Ratio Rank: 6
TPST Calmar Ratio Rank: 5
TPST Martin Ratio Rank: 5

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

RPTX vs. TPST - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Repare Therapeutics Inc. (RPTX) and Tempest Therapeutics, Inc. (TPST). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Risk / return metrics aren't available yet — we need at least 12 months of trading data to calculate them.

Sharpe Ratios by Period

	RPTX	TPST	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	—	-0.80	—
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	—	-0.04	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	-0.05	—
Sharpe Ratio (All Time) Calculated using the full available price history	—	-0.05	—

Correlation

The correlation between RPTX and TPST is 0.17, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

RPTX vs. TPST - Dividend Comparison

Neither RPTX nor TPST has paid dividends to shareholders.

Tickers have no history of dividend payments

Drawdowns

Drawdown Indicators

	RPTX	TPST	Difference
Max Drawdown Largest peak-to-trough decline	—	-100.00%	—
Max Drawdown (1Y) Largest decline over 1 year	—	-87.15%	—
Max Drawdown (5Y) Largest decline over 5 years	—	-99.52%	—
Max Drawdown (10Y) Largest decline over 10 years	—	-100.00%	—
Current Drawdown Current decline from peak	—	-100.00%	—
Average Drawdown Average peak-to-trough decline	—	-82.65%	—
Ulcer Index Depth and duration of drawdowns from previous peaks	—	49.91%	—

Volatility

Volatility by Period

	RPTX	TPST	Difference
Volatility (1M) Calculated over the trailing 1-month period	—	29.88%	—
Volatility (6M) Calculated over the trailing 6-month period	—	92.95%	—
Volatility (1Y) Calculated over the trailing 1-year period	—	103.55%	—
Volatility (5Y) Calculated over the trailing 5-year period, annualized	—	1,784.28%	—
Volatility (10Y) Calculated over the trailing 10-year period, annualized	—	1,262.43%	—

Financials