QTTB vs. DPZ

Last updated Apr 1, 2026

Compare and contrast key facts about Q32 Bio Inc (QTTB) and Domino's Pizza, Inc. (DPZ).

Performance

QTTB vs. DPZ - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Q32 Bio Inc (QTTB) and Domino's Pizza, Inc. (DPZ). The values are adjusted to include any dividend payments, if applicable.

QTTB vs. DPZ - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018
QTTB Q32 Bio Inc	93.37%	-3.49%	-68.57%	-51.75%	-65.38%	-67.76%	-45.46%	-7.42%	19.83%
DPZ Domino's Pizza, Inc.	-13.49%	0.88%	3.18%	20.69%	-37.88%	48.39%	31.63%	19.63%	6.69%

Fundamentals

Market Cap QTTB : $80.84M DPZ : $12.18B
EPS QTTB : $2.42 DPZ : $17.61K
PE Ratio QTTB : 2.66 DPZ : 0.02
Total Revenue (TTM) QTTB : $0.00 DPZ : $4.94T
Gross Profit (TTM) QTTB : -$91.00K DPZ : $1.97T
EBITDA (TTM) QTTB : $19.08M DPZ : $296.40B

Returns By Period

In the year-to-date period, QTTB achieves a 93.37% return, which is significantly higher than DPZ's -13.49% return.

QTTB

• 1D: 8.81%
• 1M: 40.79%
• YTD: 93.37%
• 6M: 224.24%
• 1Y: 289.09%
• 3Y*: -29.78%
• 5Y*: -48.26%
• 10Y*: —

DPZ

• 1D: 1.66%
• 1M: -10.41%
• YTD: -13.49%
• 6M: -16.13%
• 1Y: -20.59%
• 3Y*: 4.36%
• 5Y*: 0.52%
• 10Y*: 11.65%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

QTTB vs. DPZ — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

QTTB

QTTB Risk / Return Rank: 91
QTTB Sharpe Ratio Rank: 86
QTTB Sortino Ratio Rank: 95
QTTB Omega Ratio Rank: 92
QTTB Calmar Ratio Rank: 94
QTTB Martin Ratio Rank: 89

DPZ

DPZ Risk / Return Rank: 13
DPZ Sharpe Ratio Rank: 8
DPZ Sortino Ratio Rank: 10
DPZ Omega Ratio Rank: 12
DPZ Calmar Ratio Rank: 20
DPZ Martin Ratio Rank: 15

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

QTTB vs. DPZ - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Q32 Bio Inc (QTTB) and Domino's Pizza, Inc. (DPZ). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	QTTB	DPZ	Difference
Sharpe ratio Return per unit of total volatility	1.66	-0.84	+2.49
Sortino ratio Return per unit of downside risk	3.61	-1.15	+4.76
Omega ratio Gain probability vs. loss probability	1.43	0.87	+0.56
Calmar ratio Return relative to maximum drawdown	5.39	-0.64	+6.02
Martin ratio Return relative to average drawdown	9.99	-1.35	+11.35
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

QTTB vs. DPZ - Sharpe Ratio Comparison

The current QTTB Sharpe Ratio is 1.66, which is higher than the DPZ Sharpe Ratio of -0.84. The chart below compares the historical Sharpe Ratios of QTTB and DPZ, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	QTTB	DPZ	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.66	-0.84	+2.49
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.42	0.02	-0.43
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	0.39	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.39	0.60	-0.98

Correlation

The correlation between QTTB and DPZ is 0.10, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

QTTB vs. DPZ - Dividend Comparison

QTTB has not paid dividends to shareholders, while DPZ's dividend yield for the trailing twelve months is around 2.01%.

	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
QTTB Q32 Bio Inc	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
DPZ Domino's Pizza, Inc.	2.01%	1.67%	1.44%	1.17%	1.27%	0.67%	0.81%	0.89%	0.89%	0.97%	0.95%	1.11%

Drawdowns

QTTB vs. DPZ - Drawdown Comparison

The maximum QTTB drawdown since its inception was -99.75%, which is greater than DPZ's maximum drawdown of -86.66%. Use the drawdown chart below to compare losses from any high point for QTTB and DPZ.

Drawdown Indicators

	QTTB	DPZ	Difference
Max Drawdown Largest peak-to-trough decline	-99.75%	-86.66%	-13.09%
Max Drawdown (1Y) Largest decline over 1 year	-51.14%	-28.84%	-22.30%
Max Drawdown (5Y) Largest decline over 5 years	-99.22%	-47.81%	-51.41%
Max Drawdown (10Y) Largest decline over 10 years	—	-47.81%	—
Current Drawdown Current decline from peak	-98.82%	-32.49%	-66.33%
Average Drawdown Average peak-to-trough decline	-71.98%	-16.27%	-55.71%
Ulcer Index Depth and duration of drawdowns from previous peaks	27.56%	13.59%	+13.97%

Volatility

QTTB vs. DPZ - Volatility Comparison

Q32 Bio Inc (QTTB) has a higher volatility of 38.39% compared to Domino's Pizza, Inc. (DPZ) at 9.08%. This indicates that QTTB's price experiences larger fluctuations and is considered to be riskier than DPZ based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	QTTB	DPZ	Difference
Volatility (1M) Calculated over the trailing 1-month period	38.39%	9.08%	+29.31%
Volatility (6M) Calculated over the trailing 6-month period	90.19%	17.88%	+72.31%
Volatility (1Y) Calculated over the trailing 1-year period	175.99%	24.85%	+151.14%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	116.56%	29.21%	+87.35%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	101.19%	29.89%	+71.30%

Financials