QGEN vs. LZAGY

Last updated Apr 2, 2026

Compare and contrast key facts about Qiagen N.V. (QGEN) and Lonza Group AG (LZAGY).

Performance

QGEN vs. LZAGY - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Qiagen N.V. (QGEN) and Lonza Group AG (LZAGY). The values are adjusted to include any dividend payments, if applicable.

QGEN vs. LZAGY - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
QGEN Qiagen N.V.	-10.36%	1.51%	2.44%	-12.91%	-10.27%	5.17%	56.36%	-1.89%	11.38%	10.49%
LZAGY Lonza Group AG	-3.71%	14.70%	40.20%	-13.41%	-41.45%	30.64%	76.57%	41.02%	-2.71%	69.15%

Fundamentals

EPS QGEN : $1.98 LZAGY : $4.39
PE Ratio QGEN : 20.41 LZAGY : 14.73
PS Ratio QGEN : 4.15 LZAGY : 1.77
Total Revenue (TTM) QGEN : $2.09B LZAGY : $12.81B
Gross Profit (TTM) QGEN : $1.29B LZAGY : $4.41B
EBITDA (TTM) QGEN : $717.27M LZAGY : $2.85B

Returns By Period

In the year-to-date period, QGEN achieves a -10.36% return, which is significantly lower than LZAGY's -3.71% return. Over the past 10 years, QGEN has underperformed LZAGY with an annualized return of 5.84%, while LZAGY has yielded a comparatively higher 15.76% annualized return.

QGEN

• 1D: 0.85%
• 1M: -17.30%
• YTD: -10.36%
• 6M: -12.97%
• 1Y: 2.59%
• 3Y*: -4.12%
• 5Y*: -3.86%
• 10Y*: 5.84%

LZAGY

• 1D: 1.33%
• 1M: -4.88%
• YTD: -3.71%
• 6M: -5.23%
• 1Y: 6.34%
• 3Y*: 2.95%
• 5Y*: 2.90%
• 10Y*: 15.76%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

QGEN vs. LZAGY — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

QGEN

QGEN Risk / Return Rank: 40
QGEN Sharpe Ratio Rank: 43
QGEN Sortino Ratio Rank: 39
QGEN Omega Ratio Rank: 38
QGEN Calmar Ratio Rank: 41
QGEN Martin Ratio Rank: 41

LZAGY

LZAGY Risk / Return Rank: 45
LZAGY Sharpe Ratio Rank: 49
LZAGY Sortino Ratio Rank: 42
LZAGY Omega Ratio Rank: 40
LZAGY Calmar Ratio Rank: 46
LZAGY Martin Ratio Rank: 48

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

QGEN vs. LZAGY - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Qiagen N.V. (QGEN) and Lonza Group AG (LZAGY). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	QGEN	LZAGY	Difference
Sharpe ratio Return per unit of total volatility	0.08	0.24	-0.16
Sortino ratio Return per unit of downside risk	0.39	0.55	-0.17
Omega ratio Gain probability vs. loss probability	1.05	1.06	-0.02
Calmar ratio Return relative to maximum drawdown	0.03	0.26	-0.23
Martin ratio Return relative to average drawdown	0.09	0.72	-0.63
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

QGEN vs. LZAGY - Sharpe Ratio Comparison

The current QGEN Sharpe Ratio is 0.08, which is lower than the LZAGY Sharpe Ratio of 0.24. The chart below compares the historical Sharpe Ratios of QGEN and LZAGY, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	QGEN	LZAGY	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	0.08	0.24	-0.16
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.16	0.09	-0.25
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.22	0.53	-0.31
Sharpe Ratio (All Time) Calculated using the full available price history	0.27	0.43	-0.16

Correlation

The correlation between QGEN and LZAGY is 0.37, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

QGEN vs. LZAGY - Dividend Comparison

QGEN's dividend yield for the trailing twelve months is around 6.32%, more than LZAGY's 0.36% yield.

	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017
QGEN Qiagen N.V.	6.32%	0.56%	2.96%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	3.36%
LZAGY Lonza Group AG	0.36%	0.35%	0.38%	0.45%	0.32%	0.20%	0.13%	0.67%	1.01%	6.06%

Drawdowns

QGEN vs. LZAGY - Drawdown Comparison

The maximum QGEN drawdown since its inception was -92.14%, which is greater than LZAGY's maximum drawdown of -67.74%. Use the drawdown chart below to compare losses from any high point for QGEN and LZAGY.

Drawdown Indicators

	QGEN	LZAGY	Difference
Max Drawdown Largest peak-to-trough decline	-92.14%	-67.74%	-24.40%
Max Drawdown (1Y) Largest decline over 1 year	-29.81%	-20.23%	-9.58%
Max Drawdown (5Y) Largest decline over 5 years	-37.45%	-59.39%	+21.94%
Max Drawdown (10Y) Largest decline over 10 years	-38.61%	-59.39%	+20.78%
Current Drawdown Current decline from peak	-29.38%	-23.24%	-6.14%
Average Drawdown Average peak-to-trough decline	-47.45%	-18.56%	-28.89%
Ulcer Index Depth and duration of drawdowns from previous peaks	10.79%	7.41%	+3.38%

Volatility

QGEN vs. LZAGY - Volatility Comparison

Qiagen N.V. (QGEN) and Lonza Group AG (LZAGY) have volatilities of 8.43% and 8.10%, respectively, indicating that both stocks experience similar levels of price fluctuations. This suggests that the risk associated with both stocks, as measured by volatility, is nearly the same. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	QGEN	LZAGY	Difference
Volatility (1M) Calculated over the trailing 1-month period	8.43%	8.10%	+0.33%
Volatility (6M) Calculated over the trailing 6-month period	22.91%	18.03%	+4.88%
Volatility (1Y) Calculated over the trailing 1-year period	30.93%	26.37%	+4.56%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	24.61%	31.68%	-7.07%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	26.81%	29.70%	-2.89%

Financials

QGEN vs. LZAGY - Profitability Comparison

The chart below illustrates the profitability comparison between Qiagen N.V. and Lonza Group AG over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

QGEN - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Apr 2026, Qiagen N.V. reported a gross profit of 317.27M and revenue of 540.42M. Therefore, the gross margin over that period was 58.7%.

LZAGY - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Apr 2026, Lonza Group AG reported a gross profit of 961.99M and revenue of 2.66B. Therefore, the gross margin over that period was 36.2%.

QGEN - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Apr 2026, Qiagen N.V. reported an operating income of 153.90M and revenue of 540.42M, resulting in an operating margin of 28.5%.

LZAGY - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Apr 2026, Lonza Group AG reported an operating income of 693.32M and revenue of 2.66B, resulting in an operating margin of 26.1%.

QGEN - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Apr 2026, Qiagen N.V. reported a net income of 107.83M and revenue of 540.42M, resulting in a net margin of 20.0%.

LZAGY - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Apr 2026, Lonza Group AG reported a net income of 479.01M and revenue of 2.66B, resulting in a net margin of 18.0%.