PVLA vs. VRNA

Last updated Jun 24, 2026

PVLA (Palvella Therapeutics, Inc) and VRNA (Verona Pharma plc) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. At a 0.06 correlation, their price movements are largely independent.

Performance

PVLA vs. VRNA - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Palvella Therapeutics, Inc (PVLA) and Verona Pharma plc (VRNA). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

PVLA

• 1D: -0.13%
• 1M: 4.11%
• YTD: 13.38%
• 6M: 18.36%
• 1Y: 426.53%
• 3Y*: —
• 5Y*: —
• 10Y*: —

VRNA

• 1D: —
• 1M: —
• YTD: —
• 6M: —
• 1Y: —
• 3Y*: —
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

PVLA vs. VRNA - Yearly Performance Comparison

	2026 (YTD)	2025	2024
PVLA Palvella Therapeutics, Inc	13.38%	772.25%	-8.27%
VRNA Verona Pharma plc	0.00%	130.21%	12.12%

Correlation

The correlation between PVLA and VRNA is 0.03, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.03
Correlation (All Time) Calculated using the full available price history since Dec 16, 2024	0.06

Fundamentals

Market Cap PVLA : $1.34B VRNA : $9.72B
EPS PVLA : -$3.75 VRNA : -$0.69
PB Ratio PVLA : 47.72 VRNA : 34.92
Total Revenue (TTM) PVLA : $0.00 VRNA : $167.65M
Gross Profit (TTM) PVLA : $0.00 VRNA : $159.52M
EBITDA (TTM) PVLA : -$14.75M VRNA : -$40.86M

Return for Risk

PVLA vs. VRNA — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

PVLA

PVLA Risk / Return Rank: 97
PVLA Sharpe Ratio Rank: 99
PVLA Sortino Ratio Rank: 97
PVLA Omega Ratio Rank: 95
PVLA Calmar Ratio Rank: 99
PVLA Martin Ratio Rank: 98

VRNA

Risk / return metrics aren't available yet — we need at least 12 months of trading data to calculate them.

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

PVLA vs. VRNA - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Palvella Therapeutics, Inc (PVLA) and Verona Pharma plc (VRNA). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	PVLA	VRNA	Difference
Sharpe ratio: Return per unit of total volatility	5.32	—	—
Sortino ratio: Return per unit of downside risk	4.47	—	—
Omega ratio: Gain probability vs. loss probability	1.54	—	—
Calmar ratio: Return relative to maximum drawdown	13.82	—	—
Martin ratio: Return relative to average drawdown	31.14	—	—

Drawdowns

Drawdown Indicators

	PVLA	VRNA	Difference
Max Drawdown Largest peak-to-trough decline	-31.48%	—	—
Max Drawdown (1Y) Largest decline over 1 year	-31.11%	—	—
Current Drawdown Current decline from peak	-19.99%	—	—
Average Drawdown Average peak-to-trough decline	-11.16%	—	—
Ulcer Index Depth and duration of drawdowns from previous peaks	13.79%	—	—

Volatility

Volatility by Period

	PVLA	VRNA	Difference
Volatility (1M) Calculated over the trailing 1-month period	19.68%	—	—
Volatility (6M) Calculated over the trailing 6-month period	61.91%	—	—
Volatility (1Y) Calculated over the trailing 1-year period	80.85%	—	—
Volatility (5Y) Calculated over the trailing 5-year period, annualized	82.11%	—	—
Volatility (10Y) Calculated over the trailing 10-year period, annualized	82.11%	—	—

Dividends

PVLA vs. VRNA - Dividend Comparison

Neither PVLA nor VRNA has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both PVLA and VRNA in my portfolio?

PVLA and VRNA have a correlation of 0.03, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.