PSNL vs. ANRO
PSNL (Personalis, Inc.) and ANRO (Alto Neuroscience, Inc) are both stocks. Both are in the Healthcare sector — PSNL in Diagnostics & Research, ANRO in Biotechnology. Over the past year, PSNL returned 62.00% vs 922.59% for ANRO. At a 0.20 correlation, their price movements are largely independent.
Performance
PSNL vs. ANRO - Performance Comparison
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Returns By Period
In the year-to-date period, PSNL achieves a 26.38% return, which is significantly lower than ANRO's 37.30% return.
PSNL
- 1D
- -1.08%
- 1M
- 18.77%
- YTD
- 26.38%
- 6M
- 19.48%
- 1Y
- 62.00%
- 3Y*
- 71.91%
- 5Y*
- -17.42%
- 10Y*
- —
ANRO
- 1D
- 6.59%
- 1M
- 15.17%
- YTD
- 37.30%
- 6M
- 24.31%
- 1Y
- 922.59%
- 3Y*
- —
- 5Y*
- —
- 10Y*
- —
PSNL vs. ANRO - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | |
|---|---|---|---|
PSNL Personalis, Inc. | 26.38% | 37.72% | 348.06% |
ANRO Alto Neuroscience, Inc | 37.30% | 320.80% | -80.77% |
Correlation
The correlation between PSNL and ANRO is 0.19, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.19 |
Correlation (All Time) Calculated using the full available price history since Feb 2, 2024 | 0.20 |
Fundamentals
PSNL:
$1.05B
ANRO:
$803.90M
PSNL:
-$1.02
ANRO:
-$2.50
PSNL:
4.11
ANRO:
3.30
PSNL:
$49.04M
ANRO:
$0.00
PSNL:
-$6.62M
ANRO:
-$421.00K
PSNL:
-$90.09M
ANRO:
-$74.36M
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Return for Risk
PSNL vs. ANRO — Risk / Return Rank
PSNL
ANRO
PSNL vs. ANRO - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Personalis, Inc. (PSNL) and Alto Neuroscience, Inc (ANRO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| PSNL | ANRO | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -6.58 | ||
| Sortino ratioReturn per unit of downside risk | -4.14 | ||
| Omega ratioGain probability vs. loss probability | 1.19 | 1.72 | -0.53 |
| Calmar ratioReturn relative to maximum drawdown | 1.13 | 27.26 | -26.13 |
| Martin ratioReturn relative to average drawdown | 2.30 | 71.06 | -68.76 |
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Drawdowns
PSNL vs. ANRO - Drawdown Comparison
The maximum PSNL drawdown since its inception was -98.18%, which is greater than ANRO's maximum drawdown of -91.82%. Use the drawdown chart below to compare losses from any high point for PSNL and ANRO.
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Drawdown Indicators
| PSNL | ANRO | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -98.18% | -91.82% | -6.36% |
Max Drawdown (1Y)Largest decline over 1 year | -55.20% | -34.20% | -21.00% |
Max Drawdown (3Y)Largest decline over 3 years | -60.59% | — | — |
Max Drawdown (5Y)Largest decline over 5 years | -96.65% | — | — |
Current DrawdownCurrent decline from peak | -80.28% | -11.83% | -68.45% |
Average DrawdownAverage peak-to-trough decline | -75.73% | -53.23% | -22.50% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 27.03% | 13.09% | +13.94% |
Volatility
PSNL vs. ANRO - Volatility Comparison
Personalis, Inc. (PSNL) has a higher volatility of 27.33% compared to Alto Neuroscience, Inc (ANRO) at 24.73%. This indicates that PSNL's price experiences larger fluctuations and is considered to be riskier than ANRO based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| PSNL | ANRO | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 27.33% | 24.73% | +2.60% |
Volatility (6M)Calculated over the trailing 6-month period | 63.64% | 54.88% | +8.76% |
Volatility (1Y)Calculated over the trailing 1-year period | 93.15% | 128.63% | -35.48% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 103.25% | 115.34% | -12.09% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 98.04% | 115.34% | -17.30% |
Dividends
PSNL vs. ANRO - Dividend Comparison
Neither PSNL nor ANRO has paid dividends to shareholders.
Financials
PSNL vs. ANRO - Financials Comparison
This section allows you to compare key financial metrics between Personalis, Inc. and Alto Neuroscience, Inc. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
Frequently Asked Questions
PSNL and ANRO have a correlation of 0.19, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
PSNL has higher volatility (27.33%) compared to ANRO (24.73%). In terms of maximum drawdown, PSNL dropped -98.18% vs ANRO's -91.82%.
ANRO currently has the higher Sharpe Ratio (7.25 vs 0.67), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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