PBM vs. AGNC

Last updated Jun 4, 2026

PBM (Psyence Biomedical Ltd) and AGNC (AGNC Investment Corp.) are both stocks. PBM operates in Biotechnology (Healthcare), while AGNC operates in REIT - Mortgage (Real Estate). Over the past year, PBM returned -97.93% vs 30.16% for AGNC. At a 0.13 correlation, their price movements are largely independent.

Performance

PBM vs. AGNC - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Psyence Biomedical Ltd (PBM) and AGNC Investment Corp. (AGNC). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, PBM achieves a -86.58% return, which is significantly lower than AGNC's 0.27% return.

PBM

• 1D: 0.00%
• 1M: -40.96%
• YTD: -86.58%
• 6M: -94.32%
• 1Y: -97.93%
• 3Y*: —
• 5Y*: —
• 10Y*: —

AGNC

• 1D: -0.29%
• 1M: -3.41%
• YTD: 0.27%
• 6M: 3.92%
• 1Y: 30.16%
• 3Y*: 18.69%
• 5Y*: 1.55%
• 10Y*: 6.21%

*Multi-year figures are annualized to reflect compound growth (CAGR)

PBM vs. AGNC - Yearly Performance Comparison

	2026 (YTD)	2025	2024
PBM Psyence Biomedical Ltd	-86.58%	-95.54%	-99.41%
AGNC AGNC Investment Corp.	0.27%	34.92%	8.79%

Correlation

The correlation between PBM and AGNC is 0.02, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.02
Correlation (All Time) Calculated using the full available price history since Jan 26, 2024	0.13

The correlation between PBM and AGNC shifts across timeframes, from 0.02 (1 year) to 0.13 (all time), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap PBM : $5.85M AGNC : $11.42B
EPS PBM : -$17.56 AGNC : $1.33
PB Ratio PBM : 0.49 AGNC : 1.12
Total Revenue (TTM) PBM : $0.00 AGNC : $2.33B
Gross Profit (TTM) PBM : -$2.35K AGNC : $2.30B
EBITDA (TTM) PBM : -$1.79M AGNC : $3.72B

Return for Risk

PBM vs. AGNC — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

PBM

PBM Risk / Return Rank: 14
PBM Sharpe Ratio Rank: 23
PBM Sortino Ratio Rank: 17
PBM Omega Ratio Rank: 16
PBM Calmar Ratio Rank: 2
PBM Martin Ratio Rank: 15

AGNC

AGNC Risk / Return Rank: 76
AGNC Sharpe Ratio Rank: 82
AGNC Sortino Ratio Rank: 77
AGNC Omega Ratio Rank: 75
AGNC Calmar Ratio Rank: 70
AGNC Martin Ratio Rank: 75

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

PBM vs. AGNC - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Psyence Biomedical Ltd (PBM) and AGNC Investment Corp. (AGNC). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	PBM	AGNC	Difference
Sharpe ratio Return per unit of total volatility	-0.43	1.57	-2.00
Sortino ratio Return per unit of downside risk	-0.65	2.18	-2.83
Omega ratio Gain probability vs. loss probability	0.91	1.27	-0.36
Calmar ratio Return relative to maximum drawdown	-0.98	1.62	-2.60
Martin ratio Return relative to average drawdown	-1.21	4.90	-6.11
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

PBM vs. AGNC - Sharpe Ratio Comparison

The current PBM Sharpe Ratio is -0.43, which is lower than the AGNC Sharpe Ratio of 1.57. The chart below compares the historical Sharpe Ratios of PBM and AGNC, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	PBM	AGNC	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.43	1.57	-2.00
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	—	0.06	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	0.25	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.49	0.43	-0.91

Drawdowns

PBM vs. AGNC - Drawdown Comparison

The maximum PBM drawdown since its inception was -100.00%, which is greater than AGNC's maximum drawdown of -54.56%. Use the drawdown chart below to compare losses from any high point for PBM and AGNC.

Drawdown Indicators

	PBM	AGNC	Difference
Max Drawdown Largest peak-to-trough decline	-100.00%	-54.56%	-45.44%
Max Drawdown (1Y) Largest decline over 1 year	-99.50%	-18.71%	-80.79%
Max Drawdown (3Y) Largest decline over 3 years	—	-31.04%	—
Max Drawdown (5Y) Largest decline over 5 years	—	-54.56%	—
Max Drawdown (10Y) Largest decline over 10 years	—	-54.56%	—
Current Drawdown Current decline from peak	-100.00%	-11.67%	-88.33%
Average Drawdown Average peak-to-trough decline	-95.43%	-13.57%	-81.86%
Ulcer Index Depth and duration of drawdowns from previous peaks	80.78%	6.17%	+74.61%

Volatility

PBM vs. AGNC - Volatility Comparison

Psyence Biomedical Ltd (PBM) has a higher volatility of 25.79% compared to AGNC Investment Corp. (AGNC) at 4.78%. This indicates that PBM's price experiences larger fluctuations and is considered to be riskier than AGNC based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	PBM	AGNC	Difference
Volatility (1M) Calculated over the trailing 1-month period	25.79%	4.78%	+21.01%
Volatility (6M) Calculated over the trailing 6-month period	221.86%	15.86%	+206.00%
Volatility (1Y) Calculated over the trailing 1-year period	229.45%	19.35%	+210.10%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	203.59%	25.81%	+177.78%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	203.59%	25.38%	+178.21%

Dividends

PBM vs. AGNC - Dividend Comparison

PBM has not paid dividends to shareholders, while AGNC's dividend yield for the trailing twelve months is around 14.16%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
AGNC AGNC Investment Corp.	14.16%	13.43%	15.64%	14.68%	13.91%	9.57%	10.00%	11.31%	12.31%	10.70%	12.69%	14.30%
PBM Psyence Biomedical Ltd	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Financials

Frequently Asked Questions

Can I hold both PBM and AGNC in my portfolio?

PBM and AGNC have a correlation of 0.02, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, PBM or AGNC?

PBM has higher volatility (25.79%) compared to AGNC (4.78%). In terms of maximum drawdown, PBM dropped -100.00% vs AGNC's -54.56%.

Which has better risk-adjusted returns?

AGNC currently has the higher Sharpe Ratio (1.57 vs -0.43), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.