PACB vs. MSFT
PACB (Pacific Biosciences of California, Inc.) and MSFT (Microsoft Corporation) are both stocks. PACB operates in Diagnostics & Research (Healthcare), while MSFT operates in Software - Infrastructure (Technology). Over the past 10 years, PACB returned -16.43%/yr vs 24.97%/yr for MSFT. Their 0.23 correlation means their historical movements had little consistent relationship.
Performance
PACB vs. MSFT - Performance Comparison
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Returns By Period
In the year-to-date period, PACB achieves a -25.13% return, which is significantly lower than MSFT's -3.48% return. Over the past 10 years, PACB has underperformed MSFT with an annualized return of -16.43%, while MSFT has yielded a comparatively higher 24.97% annualized return.
PACB
- 1D
- -5.41%
- 1M
- -16.67%
- 6M
- -38.05%
- YTD
- -25.13%
- 1Y
- 5.26%
- 3Y*
- -52.83%
- 5Y*
- -46.57%
- 10Y*
- -16.43%
- ALL TIME*
- -14.49%
MSFT
- 1D
- 3.02%
- 1M
- 19.01%
- 6M
- 8.48%
- YTD
- -3.48%
- 1Y
- -10.62%
- 3Y*
- 12.25%
- 5Y*
- 11.19%
- 10Y*
- 24.97%
- ALL TIME*
- 25.16%
Liquidity Comparison
| Position | Avg. Volume Value (2W) | Avg. Volume Value (1M) | Avg. Volume Value (3M) |
|---|---|---|---|
| $17.39B | $14.79B | $16.23B | |
| $9.55M | $8.45M | $9.01M |
PACB vs. MSFT - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
PACB Pacific Biosciences of California, Inc. | -25.13% | 2.19% | -81.35% | 19.93% | -60.02% | -21.13% | 404.67% | -30.54% | 180.30% | -30.53% |
MSFT Microsoft Corporation | -3.48% | 15.58% | 12.93% | 58.19% | -28.02% | 52.48% | 42.53% | 57.56% | 20.80% | 40.73% |
Correlation
The correlation between PACB and MSFT is 0.10, which is low. Their historical price movements had little consistent relationship.
| Correlation | |
|---|---|
Correlation (1Y) Focuses on recent behavior, but can change the most. | 0.10 |
Correlation (3Y) Balances recent behavior with more history. | 0.11 |
Correlation (5Y) Shows whether the relationship held over a longer period. | 0.26 |
Correlation (10Y) Provides a long-term view across more market conditions. | 0.24 |
Correlation (All Time) Calculated using the full available price history since Oct 27, 2010 | 0.23 |
The correlation between PACB and MSFT shifts across timeframes, from 0.10 (1 year) to 0.26 (5 years), reflecting how their relationship changes across market environments.
Fundamentals
PACB:
$434.84M
MSFT:
$3.45T
PACB:
-$0.42
MSFT:
$17.94
PACB:
2.65
MSFT:
10.44
PACB:
4.09
MSFT:
7.83
PACB:
$160.03M
MSFT:
$331.84B
PACB:
$59.34M
MSFT:
$225.47B
PACB:
-$146.34M
MSFT:
$207.52B
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Return for Risk
PACB vs. MSFT — Risk / Return Rank
PACB
MSFT
PACB vs. MSFT - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Pacific Biosciences of California, Inc. (PACB) and Microsoft Corporation (MSFT). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| PACB | MSFT | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +0.40 | ||
| Sortino ratioReturn per unit of downside risk | +1.07 | ||
| Omega ratioGain probability vs. loss probability | 1.07 | 0.95 | +0.12 |
| Calmar ratioReturn relative to maximum drawdown | 0.03 | -0.35 | +0.38 |
| Martin ratioReturn relative to average drawdown | 0.04 | -0.63 | +0.67 |
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Drawdowns
PACB vs. MSFT - Drawdown Comparison
The maximum PACB drawdown since its inception was -98.22%, which is greater than MSFT's maximum drawdown of -69.38%. Use the drawdown chart below to compare losses from any high point for PACB and MSFT.
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Drawdown Indicators
| PACB | MSFT | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -98.22% | -69.38% | -28.84% |
Max Drawdown (1Y)Largest decline over 1 year | -58.05% | -34.50% | -23.55% |
Max Drawdown (3Y)Largest decline over 3 years | -92.53% | -34.50% | -58.03% |
Max Drawdown (5Y)Largest decline over 5 years | -97.40% | -37.15% | -60.25% |
Max Drawdown (10Y)Largest decline over 10 years | -98.22% | -37.15% | -61.07% |
Current DrawdownCurrent decline from peak | -97.26% | -13.73% | -83.53% |
Average DrawdownAverage peak-to-trough decline | -70.75% | -21.80% | -48.95% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 33.29% | 19.35% | +13.94% |
Volatility
PACB vs. MSFT - Volatility Comparison
Pacific Biosciences of California, Inc. (PACB) has a higher volatility of 16.84% compared to Microsoft Corporation (MSFT) at 15.97%. This indicates that PACB's price experiences larger fluctuations and is considered to be riskier than MSFT based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| PACB | MSFT | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 16.84% | 15.97% | +0.87% |
Volatility (6M)Calculated over the trailing 6-month period | 54.98% | 26.41% | +28.57% |
Volatility (1Y)Calculated over the trailing 1-year period | 85.57% | 31.93% | +53.64% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 94.62% | 28.00% | +66.62% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 84.90% | 27.62% | +57.28% |
Dividends
PACB vs. MSFT - Dividend Comparison
PACB has not paid dividends to shareholders, while MSFT's dividend yield for the trailing twelve months is around 0.77%.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
MSFT Microsoft Corporation | 0.77% | 0.70% | 0.73% | 0.74% | 1.06% | 0.68% | 0.94% | 1.20% | 1.69% | 1.86% | 2.37% | 2.33% |
PACB Pacific Biosciences of California, Inc. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
Financials
PACB vs. MSFT - Financials Comparison
This section allows you to compare key financial metrics between Pacific Biosciences of California, Inc. and Microsoft Corporation. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
Frequently Asked Questions
PACB and MSFT have a correlation of 0.10, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
PACB has higher volatility (16.84%) compared to MSFT (15.97%). In terms of maximum drawdown, PACB dropped -98.22% vs MSFT's -69.38%.
PACB currently has the higher Sharpe Ratio (0.02 vs -0.39), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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