ORKA vs. DYN

Last updated Apr 1, 2026

Compare and contrast key facts about Oruka Therapeutics, Inc (ORKA) and Dyne Therapeutics, Inc. (DYN).

Performance

ORKA vs. DYN - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Oruka Therapeutics, Inc (ORKA) and Dyne Therapeutics, Inc. (DYN). The values are adjusted to include any dividend payments, if applicable.

ORKA vs. DYN - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020
ORKA Oruka Therapeutics, Inc	61.83%	56.32%	76.73%	-28.27%	10.23%	-46.38%	-20.91%
DYN Dyne Therapeutics, Inc.	-7.31%	-16.98%	77.14%	14.75%	-2.52%	-43.38%	-12.13%

Fundamentals

EPS ORKA : -$2.25 DYN : -$3.32
Total Revenue (TTM) ORKA : $0.00 DYN : $0.00
Gross Profit (TTM) ORKA : -$28.00K DYN : $0.00
EBITDA (TTM) ORKA : -$110.20M DYN : -$433.40M

Returns By Period

In the year-to-date period, ORKA achieves a 61.83% return, which is significantly higher than DYN's -7.31% return.

ORKA

• 1D: 7.75%
• 1M: 42.55%
• YTD: 61.83%
• 6M: 155.07%
• 1Y: 378.07%
• 3Y*: 56.31%
• 5Y*: 15.11%
• 10Y*: -18.92%

DYN

• 1D: 6.09%
• 1M: 16.07%
• YTD: -7.31%
• 6M: 43.32%
• 1Y: 73.33%
• 3Y*: 16.32%
• 5Y*: 2.61%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

ORKA vs. DYN — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

ORKA

ORKA Risk / Return Rank: 98
ORKA Sharpe Ratio Rank: 99
ORKA Sortino Ratio Rank: 98
ORKA Omega Ratio Rank: 96
ORKA Calmar Ratio Rank: 98
ORKA Martin Ratio Rank: 99

DYN

DYN Risk / Return Rank: 69
DYN Sharpe Ratio Rank: 69
DYN Sortino Ratio Rank: 72
DYN Omega Ratio Rank: 71
DYN Calmar Ratio Rank: 68
DYN Martin Ratio Rank: 64

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

ORKA vs. DYN - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Oruka Therapeutics, Inc (ORKA) and Dyne Therapeutics, Inc. (DYN). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	ORKA	DYN	Difference
Sharpe ratio Return per unit of total volatility	4.96	0.81	+4.15
Sortino ratio Return per unit of downside risk	4.44	1.70	+2.73
Omega ratio Gain probability vs. loss probability	1.54	1.22	+0.31
Calmar ratio Return relative to maximum drawdown	8.62	1.31	+7.31
Martin ratio Return relative to average drawdown	37.33	2.57	+34.76
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

ORKA vs. DYN - Sharpe Ratio Comparison

The current ORKA Sharpe Ratio is 4.96, which is higher than the DYN Sharpe Ratio of 0.81. The chart below compares the historical Sharpe Ratios of ORKA and DYN, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	ORKA	DYN	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	4.96	0.81	+4.15
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.21	0.03	+0.18
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	-0.12	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.23	-0.06	-0.17

Correlation

The correlation between ORKA and DYN is 0.26, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

ORKA vs. DYN - Dividend Comparison

Neither ORKA nor DYN has paid dividends to shareholders.

	TTM	2025	2024
ORKA Oruka Therapeutics, Inc	0.00%	0.00%	99.82%
DYN Dyne Therapeutics, Inc.	0.00%	0.00%	0.00%

Drawdowns

ORKA vs. DYN - Drawdown Comparison

The maximum ORKA drawdown since its inception was -100.00%, which is greater than DYN's maximum drawdown of -85.52%. Use the drawdown chart below to compare losses from any high point for ORKA and DYN.

Drawdown Indicators

	ORKA	DYN	Difference
Max Drawdown Largest peak-to-trough decline	-100.00%	-85.52%	-14.48%
Max Drawdown (1Y) Largest decline over 1 year	-29.08%	-44.65%	+15.57%
Max Drawdown (5Y) Largest decline over 5 years	-77.76%	-85.52%	+7.76%
Max Drawdown (10Y) Largest decline over 10 years	-98.61%	—	—
Current Drawdown Current decline from peak	-100.00%	-61.46%	-38.54%
Average Drawdown Average peak-to-trough decline	-93.84%	-50.38%	-43.46%
Ulcer Index Depth and duration of drawdowns from previous peaks	7.83%	22.66%	-14.83%

Volatility

ORKA vs. DYN - Volatility Comparison

Oruka Therapeutics, Inc (ORKA) and Dyne Therapeutics, Inc. (DYN) have volatilities of 29.74% and 29.31%, respectively, indicating that both stocks experience similar levels of price fluctuations. This suggests that the risk associated with both stocks, as measured by volatility, is nearly the same. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	ORKA	DYN	Difference
Volatility (1M) Calculated over the trailing 1-month period	29.74%	29.31%	+0.43%
Volatility (6M) Calculated over the trailing 6-month period	49.10%	63.83%	-14.73%
Volatility (1Y) Calculated over the trailing 1-year period	79.04%	91.78%	-12.74%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	71.41%	79.40%	-7.99%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	152.39%	79.22%	+73.17%

Financials