NBTK.DE vs. DXSE.DE
NBTK.DE (Invesco Nasdaq Biotech UCITS ETF) and DXSE.DE (Xtrackers MSCI Europe Health Care ESG Screened UCITS ETF 1C) are both Health & Biotech Equities funds - NBTK.DE tracks the Nasdaq Biotechnology while DXSE.DE tracks the MSCI Europe Health Care ESG Screened 20-35. Both are passively managed. Over the past 5 years, NBTK.DE returned 5.63%/yr vs 5.38%/yr for DXSE.DE. A 0.54 correlation means they provide meaningful diversification when combined. NBTK.DE charges 0.40%/yr vs 0.17%/yr for DXSE.DE.
Performance
NBTK.DE vs. DXSE.DE - Performance Comparison
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Returns By Period
In the year-to-date period, NBTK.DE achieves a 4.27% return, which is significantly higher than DXSE.DE's -1.95% return.
NBTK.DE
- 1D
- 2.92%
- 1M
- 0.38%
- YTD
- 4.27%
- 6M
- 3.76%
- 1Y
- 39.20%
- 3Y*
- 9.94%
- 5Y*
- 5.63%
- 10Y*
- —
DXSE.DE
- 1D
- 2.90%
- 1M
- 0.52%
- YTD
- -1.95%
- 6M
- -0.32%
- 1Y
- 5.13%
- 3Y*
- 2.51%
- 5Y*
- 5.38%
- 10Y*
- 6.10%
NBTK.DE vs. DXSE.DE - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | |
|---|---|---|---|---|---|---|---|---|
NBTK.DE Invesco Nasdaq Biotech UCITS ETF | 4.27% | 18.60% | 4.57% | 2.51% | -6.11% | 7.46% | 14.59% | 17.24% |
DXSE.DE Xtrackers MSCI Europe Health Care ESG Screened UCITS ETF 1C | -1.95% | 4.97% | 4.52% | 9.56% | -5.75% | 25.75% | -1.94% | 10.50% |
Correlation
The correlation between NBTK.DE and DXSE.DE is 0.56, which is moderate. They share some common price drivers but move independently often enough to provide real diversification benefit when combined.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.56 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.49 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.51 |
Correlation (All Time) Calculated using the full available price history since Oct 22, 2019 | 0.54 |
The correlation between NBTK.DE and DXSE.DE has been stable across timeframes, ranging from 0.49 to 0.56 - a consistent structural relationship.
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Return for Risk
NBTK.DE vs. DXSE.DE — Risk / Return Rank
NBTK.DE
DXSE.DE
NBTK.DE vs. DXSE.DE - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Invesco Nasdaq Biotech UCITS ETF (NBTK.DE) and Xtrackers MSCI Europe Health Care ESG Screened UCITS ETF 1C (DXSE.DE). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| NBTK.DE | DXSE.DE | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +1.75 | ||
| Sortino ratioReturn per unit of downside risk | +2.33 | ||
| Omega ratioGain probability vs. loss probability | 1.34 | 1.06 | +0.28 |
| Calmar ratioReturn relative to maximum drawdown | 6.16 | 0.38 | +5.78 |
| Martin ratioReturn relative to average drawdown | 17.06 | 0.82 | +16.23 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| NBTK.DE | DXSE.DE | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 2.03 | 0.27 | +1.75 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | 0.27 | 0.32 | -0.05 |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | — | 0.38 | — |
Sharpe Ratio (All Time)Calculated using the full available price history | 0.42 | 0.45 | -0.03 |
Drawdowns
NBTK.DE vs. DXSE.DE - Drawdown Comparison
The maximum NBTK.DE drawdown since its inception was -30.99%, smaller than the maximum DXSE.DE drawdown of -34.30%. Use the drawdown chart below to compare losses from any high point for NBTK.DE and DXSE.DE.
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Drawdown Indicators
| NBTK.DE | DXSE.DE | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -30.99% | -34.30% | +3.31% |
Max Drawdown (1Y)Largest decline over 1 year | -6.24% | -12.67% | +6.43% |
Max Drawdown (3Y)Largest decline over 3 years | -29.35% | -28.10% | -1.25% |
Max Drawdown (5Y)Largest decline over 5 years | -30.99% | -28.10% | -2.89% |
Max Drawdown (10Y)Largest decline over 10 years | — | -28.10% | — |
Current DrawdownCurrent decline from peak | -1.44% | -13.88% | +12.44% |
Average DrawdownAverage peak-to-trough decline | -10.62% | -8.34% | -2.28% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 2.26% | 5.81% | -3.55% |
Volatility
NBTK.DE vs. DXSE.DE - Volatility Comparison
Invesco Nasdaq Biotech UCITS ETF (NBTK.DE) has a higher volatility of 6.41% compared to Xtrackers MSCI Europe Health Care ESG Screened UCITS ETF 1C (DXSE.DE) at 5.82%. This indicates that NBTK.DE's price experiences larger fluctuations and is considered to be riskier than DXSE.DE based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| NBTK.DE | DXSE.DE | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 6.41% | 5.82% | +0.59% |
Volatility (6M)Calculated over the trailing 6-month period | 14.11% | 11.95% | +2.16% |
Volatility (1Y)Calculated over the trailing 1-year period | 19.00% | 17.63% | +1.37% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 20.30% | 16.48% | +3.82% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 22.05% | 16.04% | +6.01% |
NBTK.DE vs. DXSE.DE - Expense Ratio Comparison
NBTK.DE has a 0.40% expense ratio, which is higher than DXSE.DE's 0.17% expense ratio.
Dividends
NBTK.DE vs. DXSE.DE - Dividend Comparison
Neither NBTK.DE nor DXSE.DE has paid dividends to shareholders.
Frequently Asked Questions
NBTK.DE and DXSE.DE have a correlation of 0.56, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
On fees, DXSE.DE is cheaper at 0.17% per year. The better choice depends on whether you care most about return, fees, risk, or income.
DXSE.DE is cheaper with a 0.17% expense ratio, compared with 0.40% for NBTK.DE.
NBTK.DE tracks Nasdaq Biotechnology, while DXSE.DE tracks MSCI Europe Health Care ESG Screened 20-35. They also come from different issuers: Invesco and Xtrackers. Their fees differ too: 0.40% for NBTK.DE and 0.17% for DXSE.DE.
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