MRNX vs. SKRE

Last updated Jul 22, 2026

MRNX (Defiance Daily Target 2X Long MRNA ETF) and SKRE (Tuttle Capital Daily 2X Inverse Regional Banks ETF) are both exchange-traded funds - MRNX is a Leveraged Equities fund actively managed by Defiance, while SKRE is a Inverse Equities fund tracking the S&P Regional Banks Select Industry. MRNX is actively managed, while SKRE is passively managed. At a correlation of -0.16, they often move in opposite directions. MRNX charges 1.31%/yr vs 0.75%/yr for SKRE.

Performance

MRNX vs. SKRE - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Defiance Daily Target 2X Long MRNA ETF (MRNX) and Tuttle Capital Daily 2X Inverse Regional Banks ETF (SKRE). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

MRNX

• 1D: 0.31%
• 1M: -20.01%
• 6M: —
• YTD: —
• 1Y: —
• 3Y*: —
• 5Y*: —
• 10Y*: —
• ALL TIME*: —

SKRE

• 1D: 0.25%
• 1M: -12.41%
• 6M: -28.50%
• YTD: -33.23%
• 1Y: -41.60%
• 3Y*: —
• 5Y*: —
• 10Y*: —
• ALL TIME*: -41.59%

*Multi-year figures are annualized to reflect compound growth (CAGR)

MRNX vs. SKRE - Yearly Performance Comparison

	2026 (YTD)
MRNX Defiance Daily Target 2X Long MRNA ETF	41.92%
SKRE Tuttle Capital Daily 2X Inverse Regional Banks ETF	-18.21%

Correlation

The correlation between MRNX and SKRE is -0.16, meaning they tend to move in opposite directions. This is especially valuable for risk management - when one declines, the other has historically tended to hold steady or rise.

	Correlation
Correlation (All Time) Calculated using the full available price history since Feb 4, 2026	-0.16

Return for Risk

MRNX vs. SKRE — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

MRNX

Risk / return metrics aren't available yet — we need at least 12 months of trading data to calculate them.

SKRE

SKRE Risk / Return Rank: 2
SKRE Sharpe Ratio Rank: 2
SKRE Sortino Ratio Rank: 3
SKRE Omega Ratio Rank: 2
SKRE Calmar Ratio Rank: 2
SKRE Martin Ratio Rank: 1

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

MRNX vs. SKRE - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Defiance Daily Target 2X Long MRNA ETF (MRNX) and Tuttle Capital Daily 2X Inverse Regional Banks ETF (SKRE). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	MRNX	SKRE	Difference
Sharpe ratio: Return per unit of total volatility	—	-0.91	—
Sortino ratio: Return per unit of downside risk	—	-1.30	—
Omega ratio: Gain probability vs. loss probability	—	0.85	—
Calmar ratio: Return relative to maximum drawdown	—	-0.81	—
Martin ratio: Return relative to average drawdown	—	-1.42	—

Drawdowns

MRNX vs. SKRE - Drawdown Comparison

The maximum MRNX drawdown since its inception was -49.28%, smaller than the maximum SKRE drawdown of -79.33%. Use the drawdown chart below to compare losses from any high point for MRNX and SKRE.

Drawdown Indicators

	MRNX	SKRE	Difference
Max Drawdown Largest peak-to-trough decline	-49.28%	-79.33%	+30.05%
Max Drawdown (1Y) Largest decline over 1 year	—	-51.44%	—
Current Drawdown Current decline from peak	-49.12%	-78.34%	+29.22%
Average Drawdown Average peak-to-trough decline	-22.18%	-48.67%	+26.49%
Ulcer Index Depth and duration of drawdowns from previous peaks	—	29.31%	—

Volatility

Volatility by Period

	MRNX	SKRE	Difference
Volatility (1M) Calculated over the trailing 1-month period	—	11.45%	—
Volatility (6M) Calculated over the trailing 6-month period	—	32.51%	—
Volatility (1Y) Calculated over the trailing 1-year period	138.23%	46.03%	+92.20%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	138.23%	55.04%	+83.19%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	138.23%	55.04%	+83.19%

MRNX vs. SKRE - Expense Ratio Comparison

MRNX has a 1.31% expense ratio, which is higher than SKRE's 0.75% expense ratio.

Dividends

MRNX vs. SKRE - Dividend Comparison

MRNX has not paid dividends to shareholders, while SKRE's dividend yield for the trailing twelve months is around 0.38%.

Position	TTM	2025	2024
MRNX Defiance Daily Target 2X Long MRNA ETF	0.00%	0.00%	0.00%
SKRE Tuttle Capital Daily 2X Inverse Regional Banks ETF	0.38%	0.26%	3.16%

Frequently Asked Questions

Can I hold both MRNX and SKRE in my portfolio?

MRNX and SKRE have a correlation of -0.16, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which ETF is better, MRNX or SKRE?

On fees, SKRE is cheaper at 0.75% per year. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF is cheaper, MRNX or SKRE?

SKRE is cheaper with a 0.75% expense ratio, compared with 1.31% for MRNX.

Which ETF pays a higher dividend yield, MRNX or SKRE?

SKRE has the higher dividend yield at 0.38%, compared with 0.00% for MRNX.

What is the main difference between MRNX and SKRE?

MRNX is categorized as Leveraged Equities, while SKRE is Inverse Equities. They also come from different issuers: Defiance and Tuttle. Their fees differ too: 1.31% for MRNX and 0.75% for SKRE.