MAZE vs. RVMD

Last updated Apr 1, 2026

Compare and contrast key facts about Maze Therapeutics, Inc (MAZE) and Revolution Medicines, Inc. (RVMD).

Performance

MAZE vs. RVMD - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Maze Therapeutics, Inc (MAZE) and Revolution Medicines, Inc. (RVMD). The values are adjusted to include any dividend payments, if applicable.

MAZE vs. RVMD - Yearly Performance Comparison

	2026 (YTD)	2025
MAZE Maze Therapeutics, Inc	-27.95%	159.75%
RVMD Revolution Medicines, Inc.	22.10%	85.45%

Fundamentals

EPS MAZE : -$2.97 RVMD : -$5.09
Total Revenue (TTM) MAZE : $0.00 RVMD : $0.00
Gross Profit (TTM) MAZE : -$649.00K RVMD : $0.00
EBITDA (TTM) MAZE : -$135.32M RVMD : -$1.00B

Returns By Period

In the year-to-date period, MAZE achieves a -27.95% return, which is significantly lower than RVMD's 22.10% return.

MAZE

• 1D: 2.90%
• 1M: -34.53%
• YTD: -27.95%
• 6M: 15.12%
• 1Y: 171.12%
• 3Y*: —
• 5Y*: —
• 10Y*: —

RVMD

• 1D: 4.90%
• 1M: -4.68%
• YTD: 22.10%
• 6M: 108.24%
• 1Y: 175.03%
• 3Y*: 64.97%
• 5Y*: 15.73%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

MAZE vs. RVMD — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

MAZE

MAZE Risk / Return Rank: 88
MAZE Sharpe Ratio Rank: 86
MAZE Sortino Ratio Rank: 85
MAZE Omega Ratio Rank: 87
MAZE Calmar Ratio Rank: 89
MAZE Martin Ratio Rank: 92

RVMD

RVMD Risk / Return Rank: 96
RVMD Sharpe Ratio Rank: 97
RVMD Sortino Ratio Rank: 97
RVMD Omega Ratio Rank: 96
RVMD Calmar Ratio Rank: 96
RVMD Martin Ratio Rank: 94

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

MAZE vs. RVMD - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Maze Therapeutics, Inc (MAZE) and Revolution Medicines, Inc. (RVMD). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	MAZE	RVMD	Difference
Sharpe ratio Return per unit of total volatility	1.67	3.21	-1.54
Sortino ratio Return per unit of downside risk	2.45	4.05	-1.60
Omega ratio Gain probability vs. loss probability	1.36	1.57	-0.21
Calmar ratio Return relative to maximum drawdown	3.67	6.43	-2.76
Martin ratio Return relative to average drawdown	12.70	15.24	-2.54
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

MAZE vs. RVMD - Sharpe Ratio Comparison

The current MAZE Sharpe Ratio is 1.67, which is lower than the RVMD Sharpe Ratio of 3.21. The chart below compares the historical Sharpe Ratios of MAZE and RVMD, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	MAZE	RVMD	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.67	3.21	-1.54
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	—	0.26	—
Sharpe Ratio (All Time) Calculated using the full available price history	0.72	0.34	+0.37

Correlation

The correlation between MAZE and RVMD is 0.22, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

MAZE vs. RVMD - Dividend Comparison

Neither MAZE nor RVMD has paid dividends to shareholders.

Tickers have no history of dividend payments

Drawdowns

MAZE vs. RVMD - Drawdown Comparison

The maximum MAZE drawdown since its inception was -52.54%, smaller than the maximum RVMD drawdown of -73.29%. Use the drawdown chart below to compare losses from any high point for MAZE and RVMD.

Drawdown Indicators

	MAZE	RVMD	Difference
Max Drawdown Largest peak-to-trough decline	-52.54%	-73.29%	+20.75%
Max Drawdown (1Y) Largest decline over 1 year	-44.03%	-24.95%	-19.08%
Max Drawdown (5Y) Largest decline over 5 years	—	-69.35%	—
Current Drawdown Current decline from peak	-42.41%	-21.11%	-21.30%
Average Drawdown Average peak-to-trough decline	-15.77%	-36.66%	+20.89%
Ulcer Index Depth and duration of drawdowns from previous peaks	12.71%	10.52%	+2.19%

Volatility

MAZE vs. RVMD - Volatility Comparison

Maze Therapeutics, Inc (MAZE) has a higher volatility of 47.05% compared to Revolution Medicines, Inc. (RVMD) at 9.83%. This indicates that MAZE's price experiences larger fluctuations and is considered to be riskier than RVMD based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	MAZE	RVMD	Difference
Volatility (1M) Calculated over the trailing 1-month period	47.05%	9.83%	+37.22%
Volatility (6M) Calculated over the trailing 6-month period	58.66%	39.79%	+18.87%
Volatility (1Y) Calculated over the trailing 1-year period	102.99%	55.11%	+47.88%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	100.77%	60.46%	+40.31%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	100.77%	64.05%	+36.72%

Financials