LYPE.DE vs. WRNA.DE
LYPE.DE (Amundi MSCI World Health Care UCITS ETF EUR Acc) and WRNA.DE (WisdomTree BioRevolution UCITS ETF USD Acc) are both Health & Biotech Equities funds - LYPE.DE tracks the MSCI World Health Care while WRNA.DE tracks the WisdomTree BioRevolution ESG Screened. Both are passively managed. Over the past 3 years, LYPE.DE returned 2.46%/yr vs 0.92%/yr for WRNA.DE. A 0.58 correlation means they provide meaningful diversification when combined. LYPE.DE charges 0.30%/yr vs 0.45%/yr for WRNA.DE.
Performance
LYPE.DE vs. WRNA.DE - Performance Comparison
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Returns By Period
In the year-to-date period, LYPE.DE achieves a -2.00% return, which is significantly lower than WRNA.DE's 10.48% return.
LYPE.DE
- 1D
- 2.79%
- 1M
- 3.48%
- YTD
- -2.00%
- 6M
- -1.61%
- 1Y
- 9.70%
- 3Y*
- 2.46%
- 5Y*
- 5.27%
- 10Y*
- 7.45%
WRNA.DE
- 1D
- 4.08%
- 1M
- 4.35%
- YTD
- 10.48%
- 6M
- 11.73%
- 1Y
- 49.24%
- 3Y*
- 0.92%
- 5Y*
- —
- 10Y*
- —
LYPE.DE vs. WRNA.DE - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | |
|---|---|---|---|---|---|---|
LYPE.DE Amundi MSCI World Health Care UCITS ETF EUR Acc | -2.00% | 2.17% | 7.03% | -0.27% | -0.17% | 4.14% |
WRNA.DE WisdomTree BioRevolution UCITS ETF USD Acc | 10.48% | 9.13% | -10.92% | -3.37% | -22.01% | -0.98% |
Correlation
The correlation between LYPE.DE and WRNA.DE is 0.56, which is moderate. They share some common price drivers but move independently often enough to provide real diversification benefit when combined.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.56 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.51 |
Correlation (All Time) Calculated using the full available price history since Dec 10, 2021 | 0.58 |
The correlation between LYPE.DE and WRNA.DE has been stable across timeframes, ranging from 0.51 to 0.58 - a consistent structural relationship.
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Return for Risk
LYPE.DE vs. WRNA.DE — Risk / Return Rank
LYPE.DE
WRNA.DE
LYPE.DE vs. WRNA.DE - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Amundi MSCI World Health Care UCITS ETF EUR Acc (LYPE.DE) and WisdomTree BioRevolution UCITS ETF USD Acc (WRNA.DE). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| LYPE.DE | WRNA.DE | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -1.07 | ||
| Sortino ratioReturn per unit of downside risk | -1.34 | ||
| Omega ratioGain probability vs. loss probability | 1.13 | 1.30 | -0.17 |
| Calmar ratioReturn relative to maximum drawdown | 0.93 | 3.61 | -2.69 |
| Martin ratioReturn relative to average drawdown | 2.27 | 9.63 | -7.36 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| LYPE.DE | WRNA.DE | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 0.68 | 1.75 | -1.07 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | 0.39 | — | — |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | 0.51 | — | — |
Sharpe Ratio (All Time)Calculated using the full available price history | 0.76 | -0.20 | +0.96 |
Drawdowns
LYPE.DE vs. WRNA.DE - Drawdown Comparison
The maximum LYPE.DE drawdown since its inception was -25.95%, smaller than the maximum WRNA.DE drawdown of -52.35%. Use the drawdown chart below to compare losses from any high point for LYPE.DE and WRNA.DE.
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Drawdown Indicators
| LYPE.DE | WRNA.DE | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -25.95% | -52.35% | +26.40% |
Max Drawdown (1Y)Largest decline over 1 year | -10.21% | -13.42% | +3.21% |
Max Drawdown (3Y)Largest decline over 3 years | -21.30% | -40.06% | +18.76% |
Max Drawdown (5Y)Largest decline over 5 years | -21.30% | — | — |
Max Drawdown (10Y)Largest decline over 10 years | -25.95% | — | — |
Current DrawdownCurrent decline from peak | -8.75% | -20.73% | +11.98% |
Average DrawdownAverage peak-to-trough decline | -5.06% | -27.26% | +22.20% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 4.18% | 5.04% | -0.86% |
Volatility
LYPE.DE vs. WRNA.DE - Volatility Comparison
The current volatility for Amundi MSCI World Health Care UCITS ETF EUR Acc (LYPE.DE) is 4.96%, while WisdomTree BioRevolution UCITS ETF USD Acc (WRNA.DE) has a volatility of 6.73%. This indicates that LYPE.DE experiences smaller price fluctuations and is considered to be less risky than WRNA.DE based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| LYPE.DE | WRNA.DE | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 4.96% | 6.73% | -1.77% |
Volatility (6M)Calculated over the trailing 6-month period | 9.76% | 17.21% | -7.45% |
Volatility (1Y)Calculated over the trailing 1-year period | 13.82% | 27.70% | -13.88% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 13.41% | 24.22% | -10.81% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 14.64% | 24.22% | -9.58% |
LYPE.DE vs. WRNA.DE - Expense Ratio Comparison
LYPE.DE has a 0.30% expense ratio, which is lower than WRNA.DE's 0.45% expense ratio.
Dividends
LYPE.DE vs. WRNA.DE - Dividend Comparison
Neither LYPE.DE nor WRNA.DE has paid dividends to shareholders.
Frequently Asked Questions
LYPE.DE and WRNA.DE have a correlation of 0.56, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
On fees, LYPE.DE is cheaper at 0.30% per year. The better choice depends on whether you care most about return, fees, risk, or income.
LYPE.DE is cheaper with a 0.30% expense ratio, compared with 0.45% for WRNA.DE.
LYPE.DE tracks MSCI World Health Care, while WRNA.DE tracks WisdomTree BioRevolution ESG Screened. They also come from different issuers: Amundi and WisdomTree. Their fees differ too: 0.30% for LYPE.DE and 0.45% for WRNA.DE.
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