INCY vs. CSCO

Last updated Jun 9, 2026

INCY (Incyte Corporation) and CSCO (Cisco Systems, Inc.) are both stocks. INCY operates in Biotechnology (Healthcare), while CSCO operates in Communication Equipment (Technology). Over the past 10 years, INCY returned 2.27%/yr vs 19.19%/yr for CSCO. At a 0.28 correlation, their price movements are largely independent.

Performance

INCY vs. CSCO - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Incyte Corporation (INCY) and Cisco Systems, Inc. (CSCO). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, INCY achieves a 1.89% return, which is significantly lower than CSCO's 62.91% return. Over the past 10 years, INCY has underperformed CSCO with an annualized return of 2.27%, while CSCO has yielded a comparatively higher 19.19% annualized return.

INCY

• 1D: -1.70%
• 1M: 2.11%
• YTD: 1.89%
• 6M: 4.07%
• 1Y: 46.34%
• 3Y*: 18.14%
• 5Y*: 3.15%
• 10Y*: 2.27%

CSCO

• 1D: 2.06%
• 1M: 28.56%
• YTD: 62.91%
• 6M: 59.13%
• 1Y: 92.26%
• 3Y*: 39.53%
• 5Y*: 21.53%
• 10Y*: 19.19%

*Multi-year figures are annualized to reflect compound growth (CAGR)

INCY vs. CSCO - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
INCY Incyte Corporation	1.89%	43.00%	10.00%	-21.83%	9.43%	-15.61%	-0.39%	37.32%	-32.86%	-5.55%
CSCO Cisco Systems, Inc.	62.91%	33.47%	21.00%	9.30%	-22.46%	45.76%	-3.49%	13.81%	16.57%	31.27%

Correlation

The correlation between INCY and CSCO is 0.05, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.05
Correlation (3Y) Calculated over the trailing 3-year period	0.20
Correlation (5Y) Calculated over the trailing 5-year period	0.24
Correlation (10Y) Calculated over the trailing 10-year period	0.27
Correlation (All Time) Calculated using the full available price history since Nov 4, 1993	0.28

Over the past year, the correlation between INCY and CSCO has dropped to 0.05 - well below their long-term average of 0.28, suggesting their price drivers have been diverging.

Fundamentals

Market Cap INCY : $20.82B CSCO : $494.99B
EPS INCY : $7.06 CSCO : $3.00
PE Ratio INCY : 14.26 CSCO : 41.42
PEG Ratio INCY : 0.01 CSCO : 34.76
PS Ratio INCY : 3.81 CSCO : 8.15
PB Ratio INCY : 3.70 CSCO : 10.13
Total Revenue (TTM) INCY : $5.36B CSCO : $60.75B
Gross Profit (TTM) INCY : $3.76B CSCO : $39.08B
EBITDA (TTM) INCY : $1.80B CSCO : $13.98B

Return for Risk

INCY vs. CSCO — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

INCY

INCY Risk / Return Rank: 79
INCY Sharpe Ratio Rank: 81
INCY Sortino Ratio Rank: 79
INCY Omega Ratio Rank: 77
INCY Calmar Ratio Rank: 80
INCY Martin Ratio Rank: 79

CSCO

CSCO Risk / Return Rank: 95
CSCO Sharpe Ratio Rank: 95
CSCO Sortino Ratio Rank: 93
CSCO Omega Ratio Rank: 95
CSCO Calmar Ratio Rank: 95
CSCO Martin Ratio Rank: 95

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

INCY vs. CSCO - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Incyte Corporation (INCY) and Cisco Systems, Inc. (CSCO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	INCY	CSCO	Difference
Sharpe ratio: Return per unit of total volatility	1.41	3.02	-1.61
Sortino ratio: Return per unit of downside risk	2.15	3.55	-1.41
Omega ratio: Gain probability vs. loss probability	1.26	1.54	-0.28
Calmar ratio: Return relative to maximum drawdown	2.54	6.83	-4.29
Martin ratio: Return relative to average drawdown	5.67	19.08	-13.40
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

INCY vs. CSCO - Sharpe Ratio Comparison

The current INCY Sharpe Ratio is 1.41, which is lower than the CSCO Sharpe Ratio of 3.02. The chart below compares the historical Sharpe Ratios of INCY and CSCO, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	INCY	CSCO	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.41	3.02	-1.61
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.11	0.87	-0.76
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.07	0.74	-0.68
Sharpe Ratio (All Time) Calculated using the full available price history	0.21	0.61	-0.40

Drawdowns

INCY vs. CSCO - Drawdown Comparison

The maximum INCY drawdown since its inception was -98.54%, which is greater than CSCO's maximum drawdown of -89.26%. Use the drawdown chart below to compare losses from any high point for INCY and CSCO.

Drawdown Indicators

	INCY	CSCO	Difference
Max Drawdown Largest peak-to-trough decline	-98.54%	-89.26%	-9.28%
Max Drawdown (1Y) Largest decline over 1 year	-18.33%	-13.57%	-4.76%
Max Drawdown (3Y) Largest decline over 3 years	-33.83%	-20.16%	-13.67%
Max Drawdown (5Y) Largest decline over 5 years	-41.53%	-36.68%	-4.85%
Max Drawdown (10Y) Largest decline over 10 years	-66.47%	-41.95%	-24.52%
Current Drawdown Current decline from peak	-34.08%	-4.50%	-29.58%
Average Drawdown Average peak-to-trough decline	-59.91%	-40.13%	-19.78%
Ulcer Index Depth and duration of drawdowns from previous peaks	8.19%	4.86%	+3.33%

Volatility

INCY vs. CSCO - Volatility Comparison

The current volatility for Incyte Corporation (INCY) is 9.23%, while Cisco Systems, Inc. (CSCO) has a volatility of 16.93%. This indicates that INCY experiences smaller price fluctuations and is considered to be less risky than CSCO based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	INCY	CSCO	Difference
Volatility (1M) Calculated over the trailing 1-month period	9.23%	16.93%	-7.70%
Volatility (6M) Calculated over the trailing 6-month period	23.30%	26.93%	-3.63%
Volatility (1Y) Calculated over the trailing 1-year period	33.04%	30.76%	+2.28%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	29.41%	24.83%	+4.58%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	34.28%	25.87%	+8.41%

Dividends

INCY vs. CSCO - Dividend Comparison

INCY has not paid dividends to shareholders, while CSCO's dividend yield for the trailing twelve months is around 1.33%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
CSCO Cisco Systems, Inc.	1.33%	2.12%	2.69%	3.07%	3.17%	2.32%	3.20%	2.88%	2.95%	2.95%	3.28%	3.02%
INCY Incyte Corporation	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Financials

INCY vs. CSCO - Profitability Comparison

The chart below illustrates the profitability comparison between Incyte Corporation and Cisco Systems, Inc. over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

INCY - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Incyte Corporation reported a gross profit of 0.00 and revenue of 1.27B. Therefore, the gross margin over that period was 0.0%.

CSCO - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Cisco Systems, Inc. reported a gross profit of 10.08B and revenue of 15.84B. Therefore, the gross margin over that period was 63.6%.

INCY - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Incyte Corporation reported an operating income of 301.12M and revenue of 1.27B, resulting in an operating margin of 23.7%.

CSCO - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Cisco Systems, Inc. reported an operating income of 3.96B and revenue of 15.84B, resulting in an operating margin of 25.0%.

INCY - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Incyte Corporation reported a net income of 303.33M and revenue of 1.27B, resulting in a net margin of 23.8%.

CSCO - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Cisco Systems, Inc. reported a net income of 3.37B and revenue of 15.84B, resulting in a net margin of 21.3%.

Frequently Asked Questions

Can I hold both INCY and CSCO in my portfolio?

INCY and CSCO have a correlation of 0.05, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, INCY or CSCO?

CSCO has higher volatility (16.93%) compared to INCY (9.23%). In terms of maximum drawdown, INCY dropped -98.54% vs CSCO's -89.26%.

Which has better risk-adjusted returns?

CSCO currently has the higher Sharpe Ratio (3.02 vs 1.41), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.