HOTH vs. VOOG

Last updated Apr 1, 2026

Compare and contrast key facts about Hoth Therapeutics, Inc. (HOTH) and Vanguard S&P 500 Growth ETF (VOOG).

VOOG is a passively managed fund by Vanguard that tracks the performance of the S&P 500 Growth Index. It was launched on Apr 5, 2019.

Performance

HOTH vs. VOOG - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Hoth Therapeutics, Inc. (HOTH) and Vanguard S&P 500 Growth ETF (VOOG). The values are adjusted to include any dividend payments, if applicable.

HOTH vs. VOOG - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019
HOTH Hoth Therapeutics, Inc.	-15.12%	32.34%	-48.05%	-81.54%	-52.72%	-72.16%	-61.71%	-27.43%
VOOG Vanguard S&P 500 Growth ETF	-8.17%	22.11%	35.89%	29.96%	-29.48%	31.95%	33.35%	18.30%

Returns By Period

In the year-to-date period, HOTH achieves a -15.12% return, which is significantly lower than VOOG's -8.17% return.

HOTH

• 1D: 9.12%
• 1M: -16.80%
• YTD: -15.12%
• 6M: -48.13%
• 1Y: -15.97%
• 3Y*: -25.84%
• 5Y*: -55.96%
• 10Y*: —

VOOG

• 1D: 4.02%
• 1M: -5.34%
• YTD: -8.17%
• 6M: -6.12%
• 1Y: 22.53%
• 3Y*: 21.80%
• 5Y*: 12.17%
• 10Y*: 15.71%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

HOTH vs. VOOG — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

HOTH

HOTH Risk / Return Rank: 36
HOTH Sharpe Ratio Rank: 34
HOTH Sortino Ratio Rank: 42
HOTH Omega Ratio Rank: 40
HOTH Calmar Ratio Rank: 32
HOTH Martin Ratio Rank: 32

VOOG

VOOG Risk / Return Rank: 66
VOOG Sharpe Ratio Rank: 61
VOOG Sortino Ratio Rank: 66
VOOG Omega Ratio Rank: 65
VOOG Calmar Ratio Rank: 70
VOOG Martin Ratio Rank: 69

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

HOTH vs. VOOG - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Hoth Therapeutics, Inc. (HOTH) and Vanguard S&P 500 Growth ETF (VOOG). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	HOTH	VOOG	Difference
Sharpe ratio Return per unit of total volatility	-0.16	1.02	-1.18
Sortino ratio Return per unit of downside risk	0.50	1.58	-1.08
Omega ratio Gain probability vs. loss probability	1.06	1.22	-0.17
Calmar ratio Return relative to maximum drawdown	-0.29	1.66	-1.96
Martin ratio Return relative to average drawdown	-0.53	6.53	-7.06
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

HOTH vs. VOOG - Sharpe Ratio Comparison

The current HOTH Sharpe Ratio is -0.16, which is lower than the VOOG Sharpe Ratio of 1.02. The chart below compares the historical Sharpe Ratios of HOTH and VOOG, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	HOTH	VOOG	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.16	1.02	-1.18
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.37	0.58	-0.94
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	0.76	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.38	0.83	-1.22

Correlation

The correlation between HOTH and VOOG is 0.19, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

HOTH vs. VOOG - Dividend Comparison

HOTH has not paid dividends to shareholders, while VOOG's dividend yield for the trailing twelve months is around 0.54%.

	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
HOTH Hoth Therapeutics, Inc.	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
VOOG Vanguard S&P 500 Growth ETF	0.54%	0.49%	0.49%	1.12%	0.93%	0.53%	0.88%	1.26%	1.34%	1.32%	1.47%	1.56%

Drawdowns

HOTH vs. VOOG - Drawdown Comparison

The maximum HOTH drawdown since its inception was -99.72%, which is greater than VOOG's maximum drawdown of -32.73%. Use the drawdown chart below to compare losses from any high point for HOTH and VOOG.

Drawdown Indicators

	HOTH	VOOG	Difference
Max Drawdown Largest peak-to-trough decline	-99.72%	-32.73%	-66.99%
Max Drawdown (1Y) Largest decline over 1 year	-62.80%	-13.71%	-49.09%
Max Drawdown (5Y) Largest decline over 5 years	-98.90%	-32.73%	-66.17%
Max Drawdown (10Y) Largest decline over 10 years	—	-32.73%	—
Current Drawdown Current decline from peak	-99.61%	-10.25%	-89.36%
Average Drawdown Average peak-to-trough decline	-83.98%	-5.00%	-78.98%
Ulcer Index Depth and duration of drawdowns from previous peaks	34.44%	3.50%	+30.94%

Volatility

HOTH vs. VOOG - Volatility Comparison

Hoth Therapeutics, Inc. (HOTH) has a higher volatility of 22.64% compared to Vanguard S&P 500 Growth ETF (VOOG) at 7.15%. This indicates that HOTH's price experiences larger fluctuations and is considered to be riskier than VOOG based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	HOTH	VOOG	Difference
Volatility (1M) Calculated over the trailing 1-month period	22.64%	7.15%	+15.49%
Volatility (6M) Calculated over the trailing 6-month period	43.22%	12.62%	+30.60%
Volatility (1Y) Calculated over the trailing 1-year period	99.77%	22.25%	+77.52%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	153.38%	21.16%	+132.22%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	140.89%	20.65%	+120.24%