GNOM.L vs. IUHC.L
GNOM.L (Global X Genomics & Biotechnology UCITS ETF) and IUHC.L (iShares S&P 500 Health Care Sector UCITS ETF USD (Acc)) are both Health & Biotech Equities funds - GNOM.L tracks the Global X Genomics & Biotechnology UCITS ETF while IUHC.L tracks the S&P 500 Capped 35/20 Health Care Index. Both are passively managed. Over the past 3 years, GNOM.L returned 4.58%/yr vs 8.05%/yr for IUHC.L. At a 0.50 correlation, their price movements are largely independent. GNOM.L charges 0.50%/yr vs 0.15%/yr for IUHC.L.
Performance
GNOM.L vs. IUHC.L - Performance Comparison
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Returns By Period
In the year-to-date period, GNOM.L achieves a 22.10% return, which is significantly higher than IUHC.L's 2.89% return.
GNOM.L
- 1D
- -0.17%
- 1M
- 11.69%
- 6M
- 15.71%
- YTD
- 22.10%
- 1Y
- 62.79%
- 3Y*
- 4.58%
- 5Y*
- —
- 10Y*
- —
IUHC.L
- 1D
- 0.47%
- 1M
- 4.22%
- 6M
- 1.83%
- YTD
- 2.89%
- 1Y
- 21.38%
- 3Y*
- 8.05%
- 5Y*
- 5.73%
- 10Y*
- 9.45%
GNOM.L vs. IUHC.L - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | |
|---|---|---|---|---|---|---|
GNOM.L Global X Genomics & Biotechnology UCITS ETF | 22.10% | 19.30% | -17.99% | -5.77% | -37.21% | -8.59% |
IUHC.L iShares S&P 500 Health Care Sector UCITS ETF USD (Acc) | 2.89% | 14.72% | 2.16% | 1.72% | -2.63% | 6.15% |
Correlation
The correlation between GNOM.L and IUHC.L is 0.50, which is moderate. They share some common price drivers but move independently often enough to provide real diversification benefit when combined.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.50 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.48 |
Correlation (All Time) Calculated using the full available price history since Nov 2, 2021 | 0.50 |
The correlation between GNOM.L and IUHC.L has been stable across timeframes, ranging from 0.47 to 0.50 - a consistent structural relationship.
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Return for Risk
GNOM.L vs. IUHC.L — Risk / Return Rank
GNOM.L
IUHC.L
GNOM.L vs. IUHC.L - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Global X Genomics & Biotechnology UCITS ETF (GNOM.L) and iShares S&P 500 Health Care Sector UCITS ETF USD (Acc) (IUHC.L). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| GNOM.L | IUHC.L | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +0.75 | ||
| Sortino ratioReturn per unit of downside risk | +0.83 | ||
| Omega ratioGain probability vs. loss probability | 1.34 | 1.24 | +0.10 |
| Calmar ratioReturn relative to maximum drawdown | 3.35 | 2.05 | +1.30 |
| Martin ratioReturn relative to average drawdown | 9.16 | 5.06 | +4.10 |
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Drawdowns
GNOM.L vs. IUHC.L - Drawdown Comparison
The maximum GNOM.L drawdown since its inception was -69.32%, which is greater than IUHC.L's maximum drawdown of -27.44%. Use the drawdown chart below to compare losses from any high point for GNOM.L and IUHC.L.
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Drawdown Indicators
| GNOM.L | IUHC.L | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -69.32% | -27.44% | -41.88% |
Max Drawdown (1Y)Largest decline over 1 year | -18.91% | -10.40% | -8.51% |
Max Drawdown (3Y)Largest decline over 3 years | -44.77% | -17.62% | -27.15% |
Max Drawdown (5Y)Largest decline over 5 years | — | -17.62% | — |
Max Drawdown (10Y)Largest decline over 10 years | — | -27.44% | — |
Current DrawdownCurrent decline from peak | -37.11% | -3.39% | -33.72% |
Average DrawdownAverage peak-to-trough decline | -47.16% | -4.88% | -42.28% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 6.92% | 4.21% | +2.71% |
Volatility
GNOM.L vs. IUHC.L - Volatility Comparison
Global X Genomics & Biotechnology UCITS ETF (GNOM.L) has a higher volatility of 8.41% compared to iShares S&P 500 Health Care Sector UCITS ETF USD (Acc) (IUHC.L) at 5.97%. This indicates that GNOM.L's price experiences larger fluctuations and is considered to be riskier than IUHC.L based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| GNOM.L | IUHC.L | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 8.41% | 5.97% | +2.44% |
Volatility (6M)Calculated over the trailing 6-month period | 22.18% | 11.61% | +10.57% |
Volatility (1Y)Calculated over the trailing 1-year period | 29.87% | 15.58% | +14.29% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 33.11% | 14.99% | +18.12% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 33.11% | 15.77% | +17.34% |
GNOM.L vs. IUHC.L - Expense Ratio Comparison
GNOM.L has a 0.50% expense ratio, which is higher than IUHC.L's 0.15% expense ratio.
Dividends
GNOM.L vs. IUHC.L - Dividend Comparison
Neither GNOM.L nor IUHC.L has paid dividends to shareholders.
Frequently Asked Questions
GNOM.L and IUHC.L have a correlation of 0.50, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
On fees, IUHC.L is cheaper at 0.15% per year. The better choice depends on whether you care most about return, fees, risk, or income.
IUHC.L is cheaper with a 0.15% expense ratio, compared with 0.50% for GNOM.L.
GNOM.L tracks Global X Genomics & Biotechnology UCITS ETF, while IUHC.L tracks S&P 500 Capped 35/20 Health Care Index. They also come from different issuers: Global X and iShares. Their fees differ too: 0.50% for GNOM.L and 0.15% for IUHC.L.
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