FTXH vs. WDNA
Compare and contrast key facts about First Trust Nasdaq Pharmaceuticals ETF (FTXH) and WisdomTree BioRevolution Fund (WDNA).
FTXH and WDNA are both exchange-traded funds (ETFs), meaning they are traded on stock exchanges and can be bought and sold throughout the day. FTXH is a passively managed fund by First Trust that tracks the performance of the Nasdaq U.S. Smart Pharmaceuticals Index. It was launched on Sep 20, 2016. WDNA is a passively managed fund by WisdomTree that tracks the performance of the WisdomTree BioRevolution Index. It was launched on Jun 3, 2021. Both FTXH and WDNA are passive ETFs, meaning that they are not actively managed but aim to replicate the performance of the underlying index as closely as possible.
Performance
FTXH vs. WDNA - Performance Comparison
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FTXH vs. WDNA - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | |
|---|---|---|---|---|---|---|
FTXH First Trust Nasdaq Pharmaceuticals ETF | 4.48% | 24.15% | 2.98% | -1.41% | 2.55% | 7.03% |
WDNA WisdomTree BioRevolution Fund | 2.99% | 22.68% | -14.18% | -2.07% | -26.29% | -5.27% |
Returns By Period
In the year-to-date period, FTXH achieves a 4.48% return, which is significantly higher than WDNA's 2.99% return.
FTXH
- 1D
- 2.61%
- 1M
- -3.36%
- YTD
- 4.48%
- 6M
- 21.14%
- 1Y
- 26.79%
- 3Y*
- 11.30%
- 5Y*
- 7.36%
- 10Y*
- —
WDNA
- 1D
- 4.08%
- 1M
- -4.89%
- YTD
- 2.99%
- 6M
- 14.31%
- 1Y
- 41.33%
- 3Y*
- 2.41%
- 5Y*
- —
- 10Y*
- —
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FTXH vs. WDNA - Expense Ratio Comparison
FTXH has a 0.60% expense ratio, which is higher than WDNA's 0.45% expense ratio.
Return for Risk
FTXH vs. WDNA — Risk / Return Rank
FTXH
WDNA
FTXH vs. WDNA - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for First Trust Nasdaq Pharmaceuticals ETF (FTXH) and WisdomTree BioRevolution Fund (WDNA). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| FTXH | WDNA | Difference | |
|---|---|---|---|
Sharpe ratioReturn per unit of total volatility | 1.28 | 1.40 | -0.13 |
Sortino ratioReturn per unit of downside risk | 1.78 | 2.06 | -0.28 |
Omega ratioGain probability vs. loss probability | 1.24 | 1.25 | -0.01 |
Calmar ratioReturn relative to maximum drawdown | 1.95 | 3.20 | -1.25 |
Martin ratioReturn relative to average drawdown | 5.94 | 7.58 | -1.64 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| FTXH | WDNA | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 1.28 | 1.40 | -0.13 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | 0.46 | — | — |
Sharpe Ratio (All Time)Calculated using the full available price history | 0.38 | -0.24 | +0.62 |
Correlation
The correlation between FTXH and WDNA is 0.67, which is considered to be moderate. This suggests that the two assets have some degree of positive relationship in their price movements. Moderate correlation can be acceptable for portfolio diversification, offering a balance between risk and potential returns.
Dividends
FTXH vs. WDNA - Dividend Comparison
FTXH's dividend yield for the trailing twelve months is around 1.23%, less than WDNA's 4.43% yield.
| TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | |
|---|---|---|---|---|---|---|---|---|---|---|---|
FTXH First Trust Nasdaq Pharmaceuticals ETF | 1.23% | 1.41% | 1.66% | 1.55% | 1.11% | 1.03% | 0.82% | 0.67% | 0.91% | 2.18% | 0.19% |
WDNA WisdomTree BioRevolution Fund | 4.43% | 4.57% | 0.75% | 0.80% | 0.38% | 0.10% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
Drawdowns
FTXH vs. WDNA - Drawdown Comparison
The maximum FTXH drawdown since its inception was -32.11%, smaller than the maximum WDNA drawdown of -58.87%. Use the drawdown chart below to compare losses from any high point for FTXH and WDNA.
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Drawdown Indicators
| FTXH | WDNA | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -32.11% | -58.87% | +26.76% |
Max Drawdown (1Y)Largest decline over 1 year | -12.74% | -11.70% | -1.04% |
Max Drawdown (5Y)Largest decline over 5 years | -19.51% | — | — |
Current DrawdownCurrent decline from peak | -3.36% | -33.71% | +30.35% |
Average DrawdownAverage peak-to-trough decline | -5.88% | -35.79% | +29.91% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 4.68% | 5.20% | -0.52% |
Volatility
FTXH vs. WDNA - Volatility Comparison
The current volatility for First Trust Nasdaq Pharmaceuticals ETF (FTXH) is 6.24%, while WisdomTree BioRevolution Fund (WDNA) has a volatility of 8.88%. This indicates that FTXH experiences smaller price fluctuations and is considered to be less risky than WDNA based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| FTXH | WDNA | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 6.24% | 8.88% | -2.64% |
Volatility (6M)Calculated over the trailing 6-month period | 12.06% | 18.59% | -6.53% |
Volatility (1Y)Calculated over the trailing 1-year period | 21.10% | 29.63% | -8.53% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 16.15% | 25.17% | -9.02% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 18.45% | 25.17% | -6.72% |