ETIHX vs. FBTAX

Last updated Jun 5, 2026

ETIHX (Eventide Healthcare & Life Sciences Fund) and FBTAX (Fidelity Advisor Biotechnology Fund Class A) are both Health & Biotech Equities funds. Over the past 10 years, ETIHX returned 11.89%/yr vs 10.67%/yr for FBTAX. Their correlation of 0.89 suggests significant overlap in exposure. ETIHX charges 1.30%/yr vs 1.00%/yr for FBTAX.

Performance

ETIHX vs. FBTAX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Eventide Healthcare & Life Sciences Fund (ETIHX) and Fidelity Advisor Biotechnology Fund Class A (FBTAX). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, ETIHX achieves a -6.48% return, which is significantly lower than FBTAX's 0.59% return. Over the past 10 years, ETIHX has outperformed FBTAX with an annualized return of 11.89%, while FBTAX has yielded a comparatively lower 10.67% annualized return.

ETIHX

• 1D: 1.02%
• 1M: -7.57%
• YTD: -6.48%
• 6M: -7.55%
• 1Y: 48.58%
• 3Y*: 9.06%
• 5Y*: 3.34%
• 10Y*: 11.89%

FBTAX

• 1D: 1.43%
• 1M: -4.75%
• YTD: 0.59%
• 6M: -3.24%
• 1Y: 46.95%
• 3Y*: 17.55%
• 5Y*: 9.43%
• 10Y*: 10.67%

*Multi-year figures are annualized to reflect compound growth (CAGR)

ETIHX vs. FBTAX - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
ETIHX Eventide Healthcare & Life Sciences Fund	-6.48%	56.73%	-10.13%	11.01%	-19.62%	-16.87%	37.12%	58.74%	-0.27%	45.83%
FBTAX Fidelity Advisor Biotechnology Fund Class A	0.59%	39.54%	5.37%	10.70%	-7.95%	-3.10%	32.17%	25.74%	-3.86%	25.80%

Correlation

The correlation between ETIHX and FBTAX is 0.86, indicating a strong positive relationship between their price movements. Combining them offers limited diversification - they tend to fall together during downturns.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.86
Correlation (3Y) Calculated over the trailing 3-year period	0.86
Correlation (5Y) Calculated over the trailing 5-year period	0.88
Correlation (10Y) Calculated over the trailing 10-year period	0.89
Correlation (All Time) Calculated using the full available price history since Jan 3, 2013	0.89

The correlation between ETIHX and FBTAX has been stable across timeframes, ranging from 0.86 to 0.89 - a consistent structural relationship.

Return for Risk

ETIHX vs. FBTAX — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

ETIHX

ETIHX Risk / Return Rank: 58
ETIHX Sharpe Ratio Rank: 50
ETIHX Sortino Ratio Rank: 45
ETIHX Omega Ratio Rank: 42
ETIHX Calmar Ratio Rank: 84
ETIHX Martin Ratio Rank: 68

FBTAX

FBTAX Risk / Return Rank: 63
FBTAX Sharpe Ratio Rank: 52
FBTAX Sortino Ratio Rank: 48
FBTAX Omega Ratio Rank: 42
FBTAX Calmar Ratio Rank: 93
FBTAX Martin Ratio Rank: 82

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

ETIHX vs. FBTAX - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Eventide Healthcare & Life Sciences Fund (ETIHX) and Fidelity Advisor Biotechnology Fund Class A (FBTAX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	ETIHX	FBTAX	Difference
Sharpe ratio: Return per unit of total volatility	2.08	2.12	-0.04
Sortino ratio: Return per unit of downside risk	2.81	2.89	-0.08
Omega ratio: Gain probability vs. loss probability	1.35	1.35	0.00
Calmar ratio: Return relative to maximum drawdown	3.94	5.23	-1.29
Martin ratio: Return relative to average drawdown	13.14	15.18	-2.04
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

ETIHX vs. FBTAX - Sharpe Ratio Comparison

The current ETIHX Sharpe Ratio is 2.08, which is comparable to the FBTAX Sharpe Ratio of 2.12. The chart below compares the historical Sharpe Ratios of ETIHX and FBTAX, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	ETIHX	FBTAX	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	2.08	2.12	-0.04
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.12	0.40	-0.28
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.42	0.44	-0.02
Sharpe Ratio (All Time) Calculated using the full available price history	0.51	0.31	+0.20

Drawdowns

ETIHX vs. FBTAX - Drawdown Comparison

The maximum ETIHX drawdown since its inception was -55.11%, smaller than the maximum FBTAX drawdown of -63.55%. Use the drawdown chart below to compare losses from any high point for ETIHX and FBTAX.

Drawdown Indicators

	ETIHX	FBTAX	Difference
Max Drawdown Largest peak-to-trough decline	-55.11%	-63.55%	+8.44%
Max Drawdown (1Y) Largest decline over 1 year	-12.50%	-8.91%	-3.59%
Max Drawdown (3Y) Largest decline over 3 years	-33.23%	-32.86%	-0.37%
Max Drawdown (5Y) Largest decline over 5 years	-49.27%	-36.51%	-12.76%
Max Drawdown (10Y) Largest decline over 10 years	-55.11%	-38.82%	-16.29%
Current Drawdown Current decline from peak	-9.94%	-7.61%	-2.33%
Average Drawdown Average peak-to-trough decline	-17.98%	-21.22%	+3.24%
Ulcer Index Depth and duration of drawdowns from previous peaks	3.74%	3.06%	+0.68%

Volatility

ETIHX vs. FBTAX - Volatility Comparison

Eventide Healthcare & Life Sciences Fund (ETIHX) has a higher volatility of 9.64% compared to Fidelity Advisor Biotechnology Fund Class A (FBTAX) at 6.88%. This indicates that ETIHX's price experiences larger fluctuations and is considered to be riskier than FBTAX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	ETIHX	FBTAX	Difference
Volatility (1M) Calculated over the trailing 1-month period	9.64%	6.88%	+2.76%
Volatility (6M) Calculated over the trailing 6-month period	18.82%	16.63%	+2.19%
Volatility (1Y) Calculated over the trailing 1-year period	23.73%	22.02%	+1.71%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	27.85%	23.48%	+4.37%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	28.40%	24.42%	+3.98%

ETIHX vs. FBTAX - Expense Ratio Comparison

ETIHX has a 1.30% expense ratio, which is higher than FBTAX's 1.00% expense ratio.

Dividends

ETIHX vs. FBTAX - Dividend Comparison

ETIHX has not paid dividends to shareholders, while FBTAX's dividend yield for the trailing twelve months is around 1.44%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
ETIHX Eventide Healthcare & Life Sciences Fund	0.00%	0.00%	0.00%	0.00%	0.00%	10.78%	3.49%	2.08%	7.33%	1.28%	0.00%	1.22%
FBTAX Fidelity Advisor Biotechnology Fund Class A	1.44%	1.45%	6.00%	1.15%	0.00%	20.12%	8.37%	6.77%	2.50%	0.00%	0.00%	5.36%

Frequently Asked Questions

Can I hold both ETIHX and FBTAX in my portfolio?

ETIHX and FBTAX have a correlation of 0.86, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, ETIHX or FBTAX?

ETIHX has higher volatility (9.64%) compared to FBTAX (6.88%). In terms of maximum drawdown, ETIHX dropped -55.11% vs FBTAX's -63.55%.

Which has better risk-adjusted returns?

FBTAX currently has the higher Sharpe Ratio (2.12 vs 2.08), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.