DYN vs. ORKA

Last updated Apr 1, 2026

Compare and contrast key facts about Dyne Therapeutics, Inc. (DYN) and Oruka Therapeutics, Inc (ORKA).

Performance

DYN vs. ORKA - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Dyne Therapeutics, Inc. (DYN) and Oruka Therapeutics, Inc (ORKA). The values are adjusted to include any dividend payments, if applicable.

DYN vs. ORKA - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020
DYN Dyne Therapeutics, Inc.	-7.31%	-16.98%	77.14%	14.75%	-2.52%	-43.38%	-12.13%
ORKA Oruka Therapeutics, Inc	61.83%	56.32%	76.73%	-28.27%	10.23%	-46.38%	-20.91%

Fundamentals

EPS DYN : -$3.32 ORKA : -$2.25
Total Revenue (TTM) DYN : $0.00 ORKA : $0.00
Gross Profit (TTM) DYN : $0.00 ORKA : -$28.00K
EBITDA (TTM) DYN : -$433.40M ORKA : -$110.20M

Returns By Period

In the year-to-date period, DYN achieves a -7.31% return, which is significantly lower than ORKA's 61.83% return.

DYN

• 1D: 6.09%
• 1M: 16.07%
• YTD: -7.31%
• 6M: 43.32%
• 1Y: 73.33%
• 3Y*: 16.32%
• 5Y*: 2.61%
• 10Y*: —

ORKA

• 1D: 7.75%
• 1M: 42.55%
• YTD: 61.83%
• 6M: 155.07%
• 1Y: 378.07%
• 3Y*: 56.31%
• 5Y*: 15.11%
• 10Y*: -18.92%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

DYN vs. ORKA — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

DYN

DYN Risk / Return Rank: 69
DYN Sharpe Ratio Rank: 69
DYN Sortino Ratio Rank: 72
DYN Omega Ratio Rank: 71
DYN Calmar Ratio Rank: 68
DYN Martin Ratio Rank: 64

ORKA

ORKA Risk / Return Rank: 98
ORKA Sharpe Ratio Rank: 99
ORKA Sortino Ratio Rank: 98
ORKA Omega Ratio Rank: 96
ORKA Calmar Ratio Rank: 98
ORKA Martin Ratio Rank: 99

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

DYN vs. ORKA - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Dyne Therapeutics, Inc. (DYN) and Oruka Therapeutics, Inc (ORKA). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	DYN	ORKA	Difference
Sharpe ratio Return per unit of total volatility	0.81	4.96	-4.15
Sortino ratio Return per unit of downside risk	1.70	4.44	-2.73
Omega ratio Gain probability vs. loss probability	1.22	1.54	-0.31
Calmar ratio Return relative to maximum drawdown	1.31	8.62	-7.31
Martin ratio Return relative to average drawdown	2.57	37.33	-34.76
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

DYN vs. ORKA - Sharpe Ratio Comparison

The current DYN Sharpe Ratio is 0.81, which is lower than the ORKA Sharpe Ratio of 4.96. The chart below compares the historical Sharpe Ratios of DYN and ORKA, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	DYN	ORKA	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	0.81	4.96	-4.15
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.03	0.21	-0.18
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	-0.12	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.06	-0.23	+0.17

Correlation

The correlation between DYN and ORKA is 0.26, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

DYN vs. ORKA - Dividend Comparison

Neither DYN nor ORKA has paid dividends to shareholders.

	TTM	2025	2024
DYN Dyne Therapeutics, Inc.	0.00%	0.00%	0.00%
ORKA Oruka Therapeutics, Inc	0.00%	0.00%	99.82%

Drawdowns

DYN vs. ORKA - Drawdown Comparison

The maximum DYN drawdown since its inception was -85.52%, smaller than the maximum ORKA drawdown of -100.00%. Use the drawdown chart below to compare losses from any high point for DYN and ORKA.

Drawdown Indicators

	DYN	ORKA	Difference
Max Drawdown Largest peak-to-trough decline	-85.52%	-100.00%	+14.48%
Max Drawdown (1Y) Largest decline over 1 year	-44.65%	-29.08%	-15.57%
Max Drawdown (5Y) Largest decline over 5 years	-85.52%	-77.76%	-7.76%
Max Drawdown (10Y) Largest decline over 10 years	—	-98.61%	—
Current Drawdown Current decline from peak	-61.46%	-100.00%	+38.54%
Average Drawdown Average peak-to-trough decline	-50.38%	-93.84%	+43.46%
Ulcer Index Depth and duration of drawdowns from previous peaks	22.66%	7.83%	+14.83%

Volatility

DYN vs. ORKA - Volatility Comparison

Dyne Therapeutics, Inc. (DYN) and Oruka Therapeutics, Inc (ORKA) have volatilities of 29.31% and 29.74%, respectively, indicating that both stocks experience similar levels of price fluctuations. This suggests that the risk associated with both stocks, as measured by volatility, is nearly the same. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	DYN	ORKA	Difference
Volatility (1M) Calculated over the trailing 1-month period	29.31%	29.74%	-0.43%
Volatility (6M) Calculated over the trailing 6-month period	63.83%	49.10%	+14.73%
Volatility (1Y) Calculated over the trailing 1-year period	91.78%	79.04%	+12.74%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	79.40%	71.41%	+7.99%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	79.22%	152.39%	-73.17%

Financials