DNTH vs. ETON

Last updated Aug 1, 2026

DNTH (Dianthus Therapeutics Inc.) and ETON (Eton Pharmaceuticals Inc) are both stocks. Both are in the Healthcare sector — DNTH in Biotechnology, ETON in Drug Manufacturers - Specialty & Generic. Over the past year, DNTH returned 419.28% vs 228.52% for ETON. Their 0.20 correlation means their historical movements had little consistent relationship.

Performance

DNTH vs. ETON - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Dianthus Therapeutics Inc. (DNTH) and Eton Pharmaceuticals Inc (ETON). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, DNTH achieves a 159.45% return, which is significantly lower than ETON's 174.51% return.

DNTH

• 1D: -5.08%
• 1M: 13.33%
• 6M: 100.26%
• YTD: 159.45%
• 1Y: 419.28%
• 3Y*: —
• 5Y*: —
• 10Y*: —
• ALL TIME*: 124.41%

ETON

• 1D: -5.32%
• 1M: 23.79%
• 6M: 209.26%
• YTD: 174.51%
• 1Y: 228.52%
• 3Y*: 154.38%
• 5Y*: 55.29%
• 10Y*: —
• ALL TIME*: 29.32%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison

Position	Avg. Volume Value (2W)	Avg. Volume Value (1M)	Avg. Volume Value (3M)
DNTH Dianthus Therapeutics Inc.	$89.59M	$95.14M	$92.66M
ETON Eton Pharmaceuticals Inc	$26.85M	$22.65M	$16.80M

DNTH vs. ETON - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023
DNTH Dianthus Therapeutics Inc.	159.45%	89.04%	109.62%	0.00%
ETON Eton Pharmaceuticals Inc	174.51%	26.95%	204.11%	-15.61%

Correlation

The correlation between DNTH and ETON is 0.20, which is low. Their historical price movements had little consistent relationship.

	Correlation
Correlation (1Y) Focuses on recent behavior, but can change the most.	0.20
Correlation (All Time) Calculated using the full available price history since Sep 12, 2023	0.20

Fundamentals

Market Cap DNTH : $4.46B ETON : $1.27B
EPS DNTH : -$0.45 ETON : -$0.05
PS Ratio DNTH : 3.09K ETON : 15.19
Total Revenue (TTM) DNTH : $873.00K ETON : $86.93M
Gross Profit (TTM) DNTH : $873.00K ETON : $47.61M
EBITDA (TTM) DNTH : -$187.38M ETON : $5.70M

Return for Risk

DNTH vs. ETON — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

DNTH

DNTH Risk / Return Rank: 99
DNTH Sharpe Ratio Rank: 100
DNTH Sortino Ratio Rank: 99
DNTH Omega Ratio Rank: 98
DNTH Calmar Ratio Rank: 100
DNTH Martin Ratio Rank: 100

ETON

ETON Risk / Return Rank: 97
ETON Sharpe Ratio Rank: 99
ETON Sortino Ratio Rank: 97
ETON Omega Ratio Rank: 97
ETON Calmar Ratio Rank: 97
ETON Martin Ratio Rank: 94

The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

DNTH vs. ETON - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Dianthus Therapeutics Inc. (DNTH) and Eton Pharmaceuticals Inc (ETON). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	DNTH	ETON	Difference
Sharpe ratio: Return per unit of total volatility	6.33	4.12	+2.22
Sortino ratio: Return per unit of downside risk	5.48	4.20	+1.28
Omega ratio: Gain probability vs. loss probability	1.69	1.55	+0.14
Calmar ratio: Return relative to maximum drawdown	20.83	6.34	+14.49
Martin ratio: Return relative to average drawdown	53.91	13.13	+40.78

DNTH vs. ETON - Sharpe Ratio Comparison

The current DNTH Sharpe Ratio is 6.33, which is higher than the ETON Sharpe Ratio of 4.12. The chart below compares the historical Sharpe Ratios of DNTH and ETON, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

DNTH vs. ETON - Drawdown Comparison

The maximum DNTH drawdown since its inception was -53.48%, smaller than the maximum ETON drawdown of -79.94%. Use the drawdown chart below to compare losses from any high point for DNTH and ETON.

Drawdown Indicators

	DNTH	ETON	Difference
Max Drawdown Largest peak-to-trough decline	-53.48%	-79.94%	+26.46%
Max Drawdown (1Y) Largest decline over 1 year	-20.20%	-36.17%	+15.97%
Max Drawdown (3Y) Largest decline over 3 years	—	-45.65%	—
Max Drawdown (5Y) Largest decline over 5 years	—	-69.35%	—
Current Drawdown Current decline from peak	-5.08%	-5.32%	+0.24%
Average Drawdown Average peak-to-trough decline	-17.26%	-36.98%	+19.72%
Ulcer Index Depth and duration of drawdowns from previous peaks	7.79%	17.44%	-9.65%

Volatility

DNTH vs. ETON - Volatility Comparison

The current volatility for Dianthus Therapeutics Inc. (DNTH) is 18.40%, while Eton Pharmaceuticals Inc (ETON) has a volatility of 20.28%. This indicates that DNTH experiences smaller price fluctuations and is considered to be less risky than ETON based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	DNTH	ETON	Difference
Volatility (1M) Calculated over the trailing 1-month period	18.40%	20.28%	-1.88%
Volatility (6M) Calculated over the trailing 6-month period	45.89%	43.44%	+2.45%
Volatility (1Y) Calculated over the trailing 1-year period	66.42%	55.80%	+10.62%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	76.88%	63.59%	+13.29%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	76.88%	63.81%	+13.07%

Dividends

DNTH vs. ETON - Dividend Comparison

Neither DNTH nor ETON has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both DNTH and ETON in my portfolio?

DNTH and ETON have a correlation of 0.20, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, DNTH or ETON?

ETON has higher volatility (20.28%) compared to DNTH (18.40%). In terms of maximum drawdown, DNTH dropped -53.48% vs ETON's -79.94%.

Which has better risk-adjusted returns?

DNTH currently has the higher Sharpe Ratio (6.33 vs 4.12), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.