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CRSP vs. TWST
Performance
Risk-Adjusted Performance
Dividends
Drawdowns
Volatility
Financials

Correlation

The correlation between CRSP and TWST is 0.45, which is considered to be moderate. This suggests that the two assets have some degree of positive relationship in their price movements. Moderate correlation can be acceptable for portfolio diversification, offering a balance between risk and potential returns.


Performance

CRSP vs. TWST - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in CRISPR Therapeutics AG (CRSP) and Twist Bioscience Corporation (TWST). The values are adjusted to include any dividend payments, if applicable.

-50.00%0.00%50.00%100.00%150.00%200.00%250.00%300.00%December2025FebruaryMarchAprilMay
8.70%
120.14%
CRSP
TWST

Key characteristics

Sharpe Ratio

CRSP:

-0.60

TWST:

-0.43

Sortino Ratio

CRSP:

-0.78

TWST:

-0.24

Omega Ratio

CRSP:

0.92

TWST:

0.97

Calmar Ratio

CRSP:

-0.42

TWST:

-0.34

Martin Ratio

CRSP:

-1.22

TWST:

-1.20

Ulcer Index

CRSP:

29.41%

TWST:

23.76%

Daily Std Dev

CRSP:

56.11%

TWST:

67.17%

Max Drawdown

CRSP:

-85.11%

TWST:

-94.48%

Current Drawdown

CRSP:

-83.04%

TWST:

-85.18%

Fundamentals

Market Cap

CRSP:

$3.25B

TWST:

$2.34B

EPS

CRSP:

-$4.34

TWST:

-$3.38

PS Ratio

CRSP:

87.07

TWST:

6.49

PB Ratio

CRSP:

1.68

TWST:

5.13

Total Revenue (TTM)

CRSP:

$36.12M

TWST:

$347.68M

Gross Profit (TTM)

CRSP:

-$93.67M

TWST:

$162.37M

EBITDA (TTM)

CRSP:

-$311.55M

TWST:

-$176.51M

Returns By Period

In the year-to-date period, CRSP achieves a -9.50% return, which is significantly higher than TWST's -33.68% return.


CRSP

YTD

-9.50%

1M

2.09%

6M

-31.00%

1Y

-33.48%

5Y*

-7.95%

10Y*

N/A

TWST

YTD

-33.68%

1M

-23.47%

6M

-32.11%

1Y

-28.66%

5Y*

-4.67%

10Y*

N/A

*Annualized

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Risk-Adjusted Performance

CRSP vs. TWST — Risk-Adjusted Performance Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

CRSP
The Risk-Adjusted Performance Rank of CRSP is 2020
Overall Rank
The Sharpe Ratio Rank of CRSP is 1919
Sharpe Ratio Rank
The Sortino Ratio Rank of CRSP is 1717
Sortino Ratio Rank
The Omega Ratio Rank of CRSP is 2020
Omega Ratio Rank
The Calmar Ratio Rank of CRSP is 2525
Calmar Ratio Rank
The Martin Ratio Rank of CRSP is 1818
Martin Ratio Rank

TWST
The Risk-Adjusted Performance Rank of TWST is 2828
Overall Rank
The Sharpe Ratio Rank of TWST is 2828
Sharpe Ratio Rank
The Sortino Ratio Rank of TWST is 3131
Sortino Ratio Rank
The Omega Ratio Rank of TWST is 3131
Omega Ratio Rank
The Calmar Ratio Rank of TWST is 3131
Calmar Ratio Rank
The Martin Ratio Rank of TWST is 1919
Martin Ratio Rank
The risk-adjusted ranks indicate the investment's position relative to the market. A rank closer to 100 signifies top-performing investments, while a rank closer to 0 might suggest underperformance, based on the selected ratio. The values are calculated based on the past 12 months of returns.

CRSP vs. TWST - Risk-Adjusted Performance Comparison

This table presents a comparison of risk-adjusted performance metrics for CRISPR Therapeutics AG (CRSP) and Twist Bioscience Corporation (TWST). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.


The current CRSP Sharpe Ratio is -0.60, which is lower than the TWST Sharpe Ratio of -0.43. The chart below compares the historical Sharpe Ratios of CRSP and TWST, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.


Rolling 12-month Sharpe Ratio-1.000.001.002.00December2025FebruaryMarchAprilMay
-0.60
-0.43
CRSP
TWST

Dividends

CRSP vs. TWST - Dividend Comparison

Neither CRSP nor TWST has paid dividends to shareholders.


Tickers have no history of dividend payments

Drawdowns

CRSP vs. TWST - Drawdown Comparison

The maximum CRSP drawdown since its inception was -85.11%, smaller than the maximum TWST drawdown of -94.48%. Use the drawdown chart below to compare losses from any high point for CRSP and TWST. For additional features, visit the drawdowns tool.


-86.00%-84.00%-82.00%-80.00%-78.00%-76.00%-74.00%December2025FebruaryMarchAprilMay
-83.04%
-85.18%
CRSP
TWST

Volatility

CRSP vs. TWST - Volatility Comparison

CRISPR Therapeutics AG (CRSP) and Twist Bioscience Corporation (TWST) have volatilities of 21.76% and 22.46%, respectively, indicating that both stocks experience similar levels of price fluctuations. This suggests that the risk associated with both stocks, as measured by volatility, is nearly the same. The chart below showcases a comparison of their rolling one-month volatility.


15.00%20.00%25.00%December2025FebruaryMarchAprilMay
21.76%
22.46%
CRSP
TWST

Financials

CRSP vs. TWST - Financials Comparison

This section allows you to compare key financial metrics between CRISPR Therapeutics AG and Twist Bioscience Corporation. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


0.00200.00M400.00M600.00M800.00M1.00B202120222023202420250
92.79M
(CRSP) Total Revenue
(TWST) Total Revenue
Values in USD except per share items