BMEA vs. API

Last updated Jun 5, 2026

BMEA (Biomea Fusion, Inc.) and API (Agora, Inc.) are both stocks. BMEA operates in Biotechnology (Healthcare), while API operates in Software - Application (Technology). Over the past 5 years, BMEA returned -40.81%/yr vs -35.54%/yr for API. At a 0.12 correlation, their price movements are largely independent.

Performance

BMEA vs. API - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Biomea Fusion, Inc. (BMEA) and Agora, Inc. (API). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, BMEA achieves a 10.48% return, which is significantly lower than API's 18.67% return.

BMEA

• 1D: 5.38%
• 1M: -9.87%
• YTD: 10.48%
• 6M: 15.13%
• 1Y: -52.10%
• 3Y*: -66.83%
• 5Y*: -40.81%
• 10Y*: —

API

• 1D: -0.82%
• 1M: 24.16%
• YTD: 18.67%
• 6M: 26.44%
• 1Y: 26.77%
• 3Y*: 17.47%
• 5Y*: -35.54%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

BMEA vs. API - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021
BMEA Biomea Fusion, Inc.	10.48%	-68.04%	-73.28%	72.24%	13.15%	-59.95%
API Agora, Inc.	18.67%	-2.16%	58.17%	-32.74%	-75.88%	-71.43%

Correlation

The correlation between BMEA and API is 0.15, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.15
Correlation (3Y) Calculated over the trailing 3-year period	0.11
Correlation (5Y) Calculated over the trailing 5-year period	0.12
Correlation (All Time) Calculated using the full available price history since Apr 19, 2021	0.12

Fundamentals

Market Cap BMEA : $99.05M API : $456.89M
EPS BMEA : -$0.58 API : $0.11
PB Ratio BMEA : 5.29 API : 0.82
Total Revenue (TTM) BMEA : $0.00 API : $145.65M
Gross Profit (TTM) BMEA : -$947.00K API : $95.03M
EBITDA (TTM) BMEA : -$60.67M API : $12.66M

Return for Risk

BMEA vs. API — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

BMEA

BMEA Risk / Return Rank: 19
BMEA Sharpe Ratio Rank: 19
BMEA Sortino Ratio Rank: 23
BMEA Omega Ratio Rank: 23
BMEA Calmar Ratio Rank: 12
BMEA Martin Ratio Rank: 18

API

API Risk / Return Rank: 59
API Sharpe Ratio Rank: 59
API Sortino Ratio Rank: 57
API Omega Ratio Rank: 55
API Calmar Ratio Rank: 61
API Martin Ratio Rank: 60

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

BMEA vs. API - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Biomea Fusion, Inc. (BMEA) and Agora, Inc. (API). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	BMEA	API	Difference
Sharpe ratio: Return per unit of total volatility	-0.53	0.51	-1.04
Sortino ratio: Return per unit of downside risk	-0.31	1.15	-1.46
Omega ratio: Gain probability vs. loss probability	0.96	1.13	-0.17
Calmar ratio: Return relative to maximum drawdown	-0.78	0.93	-1.71
Martin ratio: Return relative to average drawdown	-1.11	1.96	-3.07
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

BMEA vs. API - Sharpe Ratio Comparison

The current BMEA Sharpe Ratio is -0.53, which is lower than the API Sharpe Ratio of 0.51. The chart below compares the historical Sharpe Ratios of BMEA and API, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	BMEA	API	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.53	0.51	-1.04
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.37	-0.39	+0.02
Sharpe Ratio (All Time) Calculated using the full available price history	-0.36	-0.35	-0.01

Drawdowns

BMEA vs. API - Drawdown Comparison

The maximum BMEA drawdown since its inception was -97.71%, roughly equal to the maximum API drawdown of -98.28%. Use the drawdown chart below to compare losses from any high point for BMEA and API.

Drawdown Indicators

	BMEA	API	Difference
Max Drawdown Largest peak-to-trough decline	-97.71%	-98.28%	+0.57%
Max Drawdown (1Y) Largest decline over 1 year	-66.99%	-28.96%	-38.03%
Max Drawdown (3Y) Largest decline over 3 years	-97.71%	-60.75%	-36.96%
Max Drawdown (5Y) Largest decline over 5 years	-97.71%	-95.90%	-1.81%
Current Drawdown Current decline from peak	-96.72%	-95.45%	-1.27%
Average Drawdown Average peak-to-trough decline	-66.74%	-83.62%	+16.88%
Ulcer Index Depth and duration of drawdowns from previous peaks	47.00%	13.71%	+33.29%

Volatility

BMEA vs. API - Volatility Comparison

The current volatility for Biomea Fusion, Inc. (BMEA) is 20.06%, while Agora, Inc. (API) has a volatility of 26.80%. This indicates that BMEA experiences smaller price fluctuations and is considered to be less risky than API based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	BMEA	API	Difference
Volatility (1M) Calculated over the trailing 1-month period	20.06%	26.80%	-6.74%
Volatility (6M) Calculated over the trailing 6-month period	64.42%	38.10%	+26.32%
Volatility (1Y) Calculated over the trailing 1-year period	100.31%	52.93%	+47.38%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	110.84%	92.23%	+18.61%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	109.67%	92.74%	+16.93%

Dividends

BMEA vs. API - Dividend Comparison

Neither BMEA nor API has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both BMEA and API in my portfolio?

BMEA and API have a correlation of 0.15, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, BMEA or API?

API has higher volatility (26.80%) compared to BMEA (20.06%). In terms of maximum drawdown, BMEA dropped -97.71% vs API's -98.28%.

Which has better risk-adjusted returns?

API currently has the higher Sharpe Ratio (0.51 vs -0.53), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.