ATAI vs. XTNT

Last updated Apr 2, 2026

Compare and contrast key facts about Atai Life Sciences N.V. (ATAI) and Xtant Medical Holdings, Inc. (XTNT).

Performance

ATAI vs. XTNT - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Atai Life Sciences N.V. (ATAI) and Xtant Medical Holdings, Inc. (XTNT). The values are adjusted to include any dividend payments, if applicable.

ATAI vs. XTNT - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021
ATAI Atai Life Sciences N.V.	-9.54%	207.52%	-5.67%	-46.99%	-65.14%	-60.77%
XTNT Xtant Medical Holdings, Inc.	-32.13%	76.98%	-60.80%	71.21%	17.86%	-65.43%

Fundamentals

EPS ATAI : -$2.72 XTNT : $0.09
PS Ratio ATAI : 219.71 XTNT : 0.39
Total Revenue (TTM) ATAI : $4.09M XTNT : $133.93M
Gross Profit (TTM) ATAI : $3.08M XTNT : $84.27M
EBITDA (TTM) ATAI : -$113.05M XTNT : $22.15M

Returns By Period

In the year-to-date period, ATAI achieves a -9.54% return, which is significantly higher than XTNT's -32.13% return.

ATAI

• 1D: 4.52%
• 1M: 0.54%
• YTD: -9.54%
• 6M: -28.85%
• 1Y: 198.39%
• 3Y*: 26.91%
• 5Y*: —
• 10Y*: —

XTNT

• 1D: -4.64%
• 1M: -6.88%
• YTD: -32.13%
• 6M: -17.68%
• 1Y: 13.19%
• 3Y*: -5.85%
• 5Y*: -25.45%
• 10Y*: -33.37%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

ATAI vs. XTNT — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

ATAI

ATAI Risk / Return Rank: 88
ATAI Sharpe Ratio Rank: 93
ATAI Sortino Ratio Rank: 91
ATAI Omega Ratio Rank: 87
ATAI Calmar Ratio Rank: 88
ATAI Martin Ratio Rank: 82

XTNT

XTNT Risk / Return Rank: 48
XTNT Sharpe Ratio Rank: 47
XTNT Sortino Ratio Rank: 50
XTNT Omega Ratio Rank: 47
XTNT Calmar Ratio Rank: 48
XTNT Martin Ratio Rank: 47

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

ATAI vs. XTNT - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Atai Life Sciences N.V. (ATAI) and Xtant Medical Holdings, Inc. (XTNT). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	ATAI	XTNT	Difference
Sharpe ratio Return per unit of total volatility	2.35	0.20	+2.16
Sortino ratio Return per unit of downside risk	2.97	0.83	+2.14
Omega ratio Gain probability vs. loss probability	1.36	1.09	+0.27
Calmar ratio Return relative to maximum drawdown	3.58	0.31	+3.27
Martin ratio Return relative to average drawdown	6.67	0.61	+6.06
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

ATAI vs. XTNT - Sharpe Ratio Comparison

The current ATAI Sharpe Ratio is 2.35, which is higher than the XTNT Sharpe Ratio of 0.20. The chart below compares the historical Sharpe Ratios of ATAI and XTNT, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	ATAI	XTNT	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	2.35	0.20	+2.16
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	—	-0.34	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	-0.29	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.35	-0.30	-0.05

Correlation

The correlation between ATAI and XTNT is 0.15, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

ATAI vs. XTNT - Dividend Comparison

Neither ATAI nor XTNT has paid dividends to shareholders.

Tickers have no history of dividend payments

Drawdowns

ATAI vs. XTNT - Drawdown Comparison

The maximum ATAI drawdown since its inception was -94.77%, roughly equal to the maximum XTNT drawdown of -99.17%. Use the drawdown chart below to compare losses from any high point for ATAI and XTNT.

Drawdown Indicators

	ATAI	XTNT	Difference
Max Drawdown Largest peak-to-trough decline	-94.77%	-99.17%	+4.40%
Max Drawdown (1Y) Largest decline over 1 year	-48.06%	-42.16%	-5.90%
Max Drawdown (5Y) Largest decline over 5 years	—	-85.75%	—
Max Drawdown (10Y) Largest decline over 10 years	—	-98.84%	—
Current Drawdown Current decline from peak	-81.40%	-98.74%	+17.34%
Average Drawdown Average peak-to-trough decline	-79.80%	-88.61%	+8.81%
Ulcer Index Depth and duration of drawdowns from previous peaks	25.79%	21.49%	+4.30%

Volatility

ATAI vs. XTNT - Volatility Comparison

Atai Life Sciences N.V. (ATAI) has a higher volatility of 21.20% compared to Xtant Medical Holdings, Inc. (XTNT) at 15.23%. This indicates that ATAI's price experiences larger fluctuations and is considered to be riskier than XTNT based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	ATAI	XTNT	Difference
Volatility (1M) Calculated over the trailing 1-month period	21.20%	15.23%	+5.97%
Volatility (6M) Calculated over the trailing 6-month period	53.28%	42.78%	+10.50%
Volatility (1Y) Calculated over the trailing 1-year period	85.32%	67.76%	+17.56%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	84.10%	74.22%	+9.88%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	84.10%	113.62%	-29.52%

Financials