AMGN vs. ITUB
AMGN (Amgen Inc.) and ITUB (Itaú Unibanco Holding S.A.) are both stocks. AMGN operates in Drug Manufacturers - General (Healthcare), while ITUB operates in Banks - Regional (Financial Services). Over the past 10 years, AMGN returned 12.08%/yr vs 18.25%/yr for ITUB. At a 0.23 correlation, their price movements are largely independent.
Performance
AMGN vs. ITUB - Performance Comparison
Loading charts...
Returns By Period
In the year-to-date period, AMGN achieves a 10.10% return, which is significantly lower than ITUB's 12.88% return. Over the past 10 years, AMGN has underperformed ITUB with an annualized return of 12.08%, while ITUB has yielded a comparatively higher 18.25% annualized return.
AMGN
- 1D
- 0.32%
- 1M
- 6.37%
- YTD
- 10.10%
- 6M
- 13.41%
- 1Y
- 23.07%
- 3Y*
- 20.61%
- 5Y*
- 11.36%
- 10Y*
- 12.08%
ITUB
- 1D
- 1.01%
- 1M
- 1.83%
- YTD
- 12.88%
- 6M
- 13.72%
- 1Y
- 35.09%
- 3Y*
- 26.58%
- 5Y*
- 23.47%
- 10Y*
- 18.25%
AMGN vs. ITUB - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
AMGN Amgen Inc. | 10.10% | 29.67% | -6.77% | 13.46% | 20.43% | 0.87% | -1.99% | 27.60% | 15.23% | 22.27% |
ITUB Itaú Unibanco Holding S.A. | 12.88% | 86.06% | -23.49% | 54.53% | 30.82% | -6.05% | -30.47% | 8.46% | 12.68% | 30.90% |
Correlation
The correlation between AMGN and ITUB is 0.23, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.23 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.19 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.19 |
Correlation (10Y) Calculated over the trailing 10-year period | 0.19 |
Correlation (All Time) Calculated using the full available price history since Feb 25, 2002 | 0.23 |
Fundamentals
AMGN:
$193.23B
ITUB:
$88.83B
AMGN:
$14.38
ITUB:
R$4.00
AMGN:
24.70
ITUB:
10.19
AMGN:
1.42
ITUB:
1.01
AMGN:
5.17
ITUB:
1.21
AMGN:
21.03
ITUB:
2.08
AMGN:
$37.24B
ITUB:
R$384.43B
AMGN:
$26.61B
ITUB:
R$131.20B
AMGN:
$17.27B
ITUB:
R$54.38B
Compare stocks, funds, or ETFs
Search for stocks, ETFs, and funds for a quick comparison or use the comparison tool for more options.
Return for Risk
AMGN vs. ITUB — Risk / Return Rank
AMGN
ITUB
AMGN vs. ITUB - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Amgen Inc. (AMGN) and Itaú Unibanco Holding S.A. (ITUB). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| AMGN | ITUB | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -0.30 | ||
| Sortino ratioReturn per unit of downside risk | -0.24 | ||
| Omega ratioGain probability vs. loss probability | 1.17 | 1.20 | -0.03 |
| Calmar ratioReturn relative to maximum drawdown | 1.40 | 1.64 | -0.24 |
| Martin ratioReturn relative to average drawdown | 3.22 | 4.32 | -1.10 |
Loading charts...
Drawdowns
AMGN vs. ITUB - Drawdown Comparison
The maximum AMGN drawdown since its inception was -63.48%, smaller than the maximum ITUB drawdown of -69.35%. Use the drawdown chart below to compare losses from any high point for AMGN and ITUB.
Loading charts...
Drawdown Indicators
| AMGN | ITUB | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -63.48% | -69.35% | +5.87% |
Max Drawdown (1Y)Largest decline over 1 year | -16.57% | -21.53% | +4.96% |
Max Drawdown (3Y)Largest decline over 3 years | -22.74% | -28.17% | +5.43% |
Max Drawdown (5Y)Largest decline over 5 years | -24.86% | -31.59% | +6.73% |
Max Drawdown (10Y)Largest decline over 10 years | -24.86% | -61.96% | +37.10% |
Current DrawdownCurrent decline from peak | -7.80% | -15.62% | +7.82% |
Average DrawdownAverage peak-to-trough decline | -16.77% | -21.01% | +4.24% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 7.19% | 8.14% | -0.95% |
Volatility
AMGN vs. ITUB - Volatility Comparison
The current volatility for Amgen Inc. (AMGN) is 7.92%, while Itaú Unibanco Holding S.A. (ITUB) has a volatility of 9.45%. This indicates that AMGN experiences smaller price fluctuations and is considered to be less risky than ITUB based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
Loading charts...
Volatility by Period
| AMGN | ITUB | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 7.92% | 9.45% | -1.53% |
Volatility (6M)Calculated over the trailing 6-month period | 19.22% | 25.03% | -5.81% |
Volatility (1Y)Calculated over the trailing 1-year period | 27.79% | 31.11% | -3.32% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 23.97% | 33.91% | -9.94% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 24.86% | 38.44% | -13.58% |
Dividends
AMGN vs. ITUB - Dividend Comparison
AMGN's dividend yield for the trailing twelve months is around 2.76%, less than ITUB's 7.27% yield.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
AMGN Amgen Inc. | 2.76% | 2.91% | 3.45% | 2.96% | 2.95% | 3.13% | 2.78% | 2.41% | 2.71% | 2.65% | 2.74% | 1.95% |
ITUB Itaú Unibanco Holding S.A. | 7.27% | 11.26% | 9.20% | 3.61% | 4.21% | 29.81% | 4.80% | 8.21% | 6.93% | 3.35% | 15.63% | 3.89% |
Financials
AMGN vs. ITUB - Financials Comparison
This section allows you to compare key financial metrics between Amgen Inc. and Itaú Unibanco Holding S.A.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
AMGN vs. ITUB - Profitability Comparison
AMGN - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Amgen Inc. reported a gross profit of 5.87B and revenue of 8.62B. Therefore, the gross margin over that period was 68.2%.
ITUB - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Itaú Unibanco Holding S.A. reported a gross profit of 32.47B and revenue of 94.91B. Therefore, the gross margin over that period was 34.2%.
AMGN - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Amgen Inc. reported an operating income of 2.67B and revenue of 8.62B, resulting in an operating margin of 30.9%.
ITUB - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Itaú Unibanco Holding S.A. reported an operating income of 12.47B and revenue of 94.91B, resulting in an operating margin of 13.1%.
AMGN - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Amgen Inc. reported a net income of 1.82B and revenue of 8.62B, resulting in a net margin of 21.1%.
ITUB - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Itaú Unibanco Holding S.A. reported a net income of 11.42B and revenue of 94.91B, resulting in a net margin of 12.0%.
Frequently Asked Questions
AMGN and ITUB have a correlation of 0.23, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
ITUB has higher volatility (9.45%) compared to AMGN (7.92%). In terms of maximum drawdown, AMGN dropped -63.48% vs ITUB's -69.35%.
ITUB currently has the higher Sharpe Ratio (1.13 vs 0.84), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
Find the right allocation for AMGN and ITUB
Add both to a portfolio and optimize allocations for your target — whether that's maximizing returns, minimizing drawdowns, or balancing risk across holdings.
Open Portfolio Optimizer