ABSI vs. MRK

Last updated Jun 4, 2026

ABSI (Absci Corporation) and MRK (Merck & Co., Inc.) are both stocks. Both are in the Healthcare sector — ABSI in Biotechnology, MRK in Drug Manufacturers - General. Over the past 3 years, ABSI returned 46.74%/yr vs 3.77%/yr for MRK. At a 0.02 correlation, their price movements are largely independent.

Performance

ABSI vs. MRK - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Absci Corporation (ABSI) and Merck & Co., Inc. (MRK). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, ABSI achieves a 70.20% return, which is significantly higher than MRK's 9.78% return.

ABSI

• 1D: -6.46%
• 1M: 5.69%
• YTD: 70.20%
• 6M: 80.55%
• 1Y: 113.67%
• 3Y*: 46.74%
• 5Y*: —
• 10Y*: —

MRK

• 1D: -0.82%
• 1M: 1.41%
• YTD: 9.78%
• 6M: 13.95%
• 1Y: 54.09%
• 3Y*: 3.77%
• 5Y*: 12.62%
• 10Y*: 11.18%

*Multi-year figures are annualized to reflect compound growth (CAGR)

ABSI vs. MRK - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021
ABSI Absci Corporation	70.20%	33.21%	-37.62%	100.00%	-74.39%	-62.02%
MRK Merck & Co., Inc.	9.78%	9.79%	-6.26%	1.01%	49.42%	2.00%

Correlation

The correlation between ABSI and MRK is 0.07, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.07
Correlation (3Y) Calculated over the trailing 3-year period	0.02
Correlation (All Time) Calculated using the full available price history since Jul 23, 2021	0.02

Fundamentals

Market Cap ABSI : $908.59M MRK : $283.54B
EPS ABSI : -$0.82 MRK : $3.58
PS Ratio ABSI : 526.70 MRK : 4.36
PB Ratio ABSI : 5.28 MRK : 6.18
Total Revenue (TTM) ABSI : $1.62M MRK : $65.59B
Gross Profit (TTM) ABSI : -$21.67M MRK : $49.79B
EBITDA (TTM) ABSI : -$115.23M MRK : $22.69B

Return for Risk

ABSI vs. MRK — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

ABSI

ABSI Risk / Return Rank: 74
ABSI Sharpe Ratio Rank: 76
ABSI Sortino Ratio Rank: 76
ABSI Omega Ratio Rank: 73
ABSI Calmar Ratio Rank: 75
ABSI Martin Ratio Rank: 70

MRK

MRK Risk / Return Rank: 87
MRK Sharpe Ratio Rank: 88
MRK Sortino Ratio Rank: 87
MRK Omega Ratio Rank: 84
MRK Calmar Ratio Rank: 90
MRK Martin Ratio Rank: 89

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

ABSI vs. MRK - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Absci Corporation (ABSI) and Merck & Co., Inc. (MRK). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	ABSI	MRK	Difference
Sharpe ratio: Return per unit of total volatility	1.23	2.02	-0.79
Sortino ratio: Return per unit of downside risk	2.12	2.94	-0.82
Omega ratio: Gain probability vs. loss probability	1.25	1.35	-0.10
Calmar ratio: Return relative to maximum drawdown	2.12	4.78	-2.67
Martin ratio: Return relative to average drawdown	3.89	12.00	-8.11
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

ABSI vs. MRK - Sharpe Ratio Comparison

The current ABSI Sharpe Ratio is 1.23, which is lower than the MRK Sharpe Ratio of 2.02. The chart below compares the historical Sharpe Ratios of ABSI and MRK, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	ABSI	MRK	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.23	2.02	-0.79
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	—	0.54	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	0.49	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.24	0.48	-0.72

Drawdowns

ABSI vs. MRK - Drawdown Comparison

The maximum ABSI drawdown since its inception was -96.20%, which is greater than MRK's maximum drawdown of -68.61%. Use the drawdown chart below to compare losses from any high point for ABSI and MRK.

Drawdown Indicators

	ABSI	MRK	Difference
Max Drawdown Largest peak-to-trough decline	-96.20%	-68.61%	-27.59%
Max Drawdown (1Y) Largest decline over 1 year	-54.00%	-11.37%	-42.63%
Max Drawdown (3Y) Largest decline over 3 years	-66.06%	-43.44%	-22.62%
Max Drawdown (5Y) Largest decline over 5 years	—	-43.44%	—
Max Drawdown (10Y) Largest decline over 10 years	—	-43.44%	—
Current Drawdown Current decline from peak	-80.39%	-8.50%	-71.89%
Average Drawdown Average peak-to-trough decline	-84.80%	-18.84%	-65.96%
Ulcer Index Depth and duration of drawdowns from previous peaks	29.32%	4.52%	+24.80%

Volatility

ABSI vs. MRK - Volatility Comparison

Absci Corporation (ABSI) has a higher volatility of 28.30% compared to Merck & Co., Inc. (MRK) at 8.21%. This indicates that ABSI's price experiences larger fluctuations and is considered to be riskier than MRK based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	ABSI	MRK	Difference
Volatility (1M) Calculated over the trailing 1-month period	28.30%	8.21%	+20.09%
Volatility (6M) Calculated over the trailing 6-month period	65.46%	17.62%	+47.84%
Volatility (1Y) Calculated over the trailing 1-year period	93.26%	26.92%	+66.34%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	96.53%	23.62%	+72.91%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	96.53%	22.91%	+73.62%

Dividends

ABSI vs. MRK - Dividend Comparison

ABSI has not paid dividends to shareholders, while MRK's dividend yield for the trailing twelve months is around 2.89%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
ABSI Absci Corporation	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
MRK Merck & Co., Inc.	2.89%	3.12%	3.14%	2.72%	2.52%	3.41%	3.03%	2.48%	2.60%	3.36%	3.14%	3.43%

Financials

Frequently Asked Questions

Can I hold both ABSI and MRK in my portfolio?

ABSI and MRK have a correlation of 0.07, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, ABSI or MRK?

ABSI has higher volatility (28.30%) compared to MRK (8.21%). In terms of maximum drawdown, ABSI dropped -96.20% vs MRK's -68.61%.

Which has better risk-adjusted returns?

MRK currently has the higher Sharpe Ratio (2.02 vs 1.23), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.