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2seventy bio, Inc. (TSVT)
Performance
Risk-Adjusted Performance
Dividends
Drawdowns
Volatility
Financials

Company Info

ISIN

US9013841070

CUSIP

901384107

IPO Date

Nov 3, 2021

Highlights

Market Cap

$266.14M

EPS (TTM)

-$0.08

Total Revenue (TTM)

$48.37M

Gross Profit (TTM)

$1.45M

EBITDA (TTM)

-$53.99M

Year Range

$2.29 - $5.30

Target Price

$5.00

Short %

5.07%

Short Ratio

2.44

Share Price Chart


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2seventy bio, Inc.

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Performance

Performance Chart


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S&P 500

Returns By Period

2seventy bio, Inc. (TSVT) returned 70.07% year-to-date (YTD) and 14.68% over the past 12 months.


TSVT

YTD

70.07%

1M

0.20%

6M

25.31%

1Y

14.68%

3Y*

-26.02%

5Y*

N/A

10Y*

N/A

^GSPC (Benchmark)

YTD

0.51%

1M

6.15%

6M

-2.00%

1Y

12.92%

3Y*

12.68%

5Y*

14.19%

10Y*

10.85%

*Annualized

Monthly Returns

The table below presents the monthly returns of TSVT, with color gradation from worst to best to easily spot seasonal factors. Returns are adjusted for dividends.


JanFebMarAprMayJunJulAugSepOctNovDecTotal
2025-9.52%-0.75%87.12%1.01%0.20%70.07%
202420.37%1.17%2.88%-14.77%-7.24%-8.98%22.60%3.18%-3.08%-8.05%-8.06%-26.32%-31.15%
202345.14%-0.81%-24.39%-6.76%25.24%-15.03%-25.00%-31.62%-24.47%-37.76%-25.00%133.33%-54.43%
2022-27.16%-20.51%14.96%-21.10%-7.88%6.45%9.02%2.36%-1.22%9.14%-1.32%-40.20%-63.44%
202191.29%-2.70%86.13%
Go deeper with the Portfolio Analysis tool — backtest performance, assess risk, compare to benchmarks, and more

Risk-Adjusted Performance

Risk-Adjusted Performance Rank

The current rank of TSVT is 61, indicating average performance compared to other stocks on our website. Here’s a breakdown of how it compares using common performance measures.


The Risk-Adjusted Performance Rank of TSVT is 6161
Overall Rank
The Sharpe Ratio Rank of TSVT is 5454
Sharpe Ratio Rank
The Sortino Ratio Rank of TSVT is 6969
Sortino Ratio Rank
The Omega Ratio Rank of TSVT is 6666
Omega Ratio Rank
The Calmar Ratio Rank of TSVT is 5858
Calmar Ratio Rank
The Martin Ratio Rank of TSVT is 5858
Martin Ratio Rank
The risk-adjusted ranks indicate the investment's position relative to the market. A rank closer to 100 signifies top-performing investments, while a rank closer to 0 might suggest underperformance, based on the selected ratio. The values are calculated based on the past 12 months of returns.

Risk-Adjusted Performance Indicators

The charts below present risk-adjusted performance metrics for 2seventy bio, Inc. (TSVT) and compare them to a chosen benchmark (^GSPC). These indicators evaluate an investment's returns against its associated risks.


The Sharpe ratio helps investors understand how much return they're getting for the level of risk taken. A higher Sharpe ratio indicates better risk-adjusted performance, meaning more reward for each unit of risk.

2seventy bio, Inc. Sharpe ratios as of May 31, 2025 (values are recalculated daily):

  • 1-Year: 0.10
  • All Time: -0.24

These values reflect how efficiently the investment has delivered returns relative to its volatility over different time periods. All figures are annualized and based on daily total returns (including price changes and dividends).

The chart below shows the rolling Sharpe ratio of 2seventy bio, Inc. compared to the selected benchmark. This view highlights how the investment's risk-adjusted performance has changed over time.


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Go to the full Sharpe Ratio tool to analyze any stock or portfolio. Customize time frames, set your own risk-free rate, and more

Dividends

Dividend History


2seventy bio, Inc. doesn't pay dividends

Drawdowns

Drawdowns Chart

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.


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Worst Drawdowns

The table below displays the maximum drawdowns of the 2seventy bio, Inc.. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the 2seventy bio, Inc. was 96.31%, occurring on Nov 21, 2023. The portfolio has not yet recovered.

The current 2seventy bio, Inc. drawdown is 88.25%.


Depth

Start

To Bottom

Bottom

To Recover

End

Total

-96.31%Nov 10, 2021511Nov 21, 2023
Go to the full Drawdowns tool for more analysis options, including inflation-adjusted drawdowns, and more

Volatility

Volatility Chart

The chart below shows the rolling one-month volatility.


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Financials

Financial Performance

The chart below illustrates the trends in the financial health of 2seventy bio, Inc. over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.


Annual
Quarterly

0.0

Earnings Per Share

The chart presents the Earnings Per Share (EPS) performance of 2seventy bio, Inc., comparing actual results with analytics estimates. The company has exceeded analyst expectations for EPS in the past quarter, achieving a 101.2% positive surprise.


-4.00-3.00-2.00-1.000.002021AprilJulyOctober2022AprilJulyOctober2023AprilJulyOctober2024AprilJulyOctober2025
0.01
-0.81
Actual
Estimate

Valuation

The Valuation section provides an overview of how 2seventy bio, Inc. is priced in the market compared to other companies in the Drug Manufacturers - General industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.


PS Ratio

This chart shows the Price-to-Sales (P/S) ratio for TSVT relative to other companies in the Drug Manufacturers - General industry. Currently, TSVT has a P/S ratio of 5.5. This P/S ratio is high relative to other companies in the industry. It could mean the stock is overvalued, or that investors expect strong future growth and profitability.

PB Ratio

The chart illustrates the Price-to-Book (P/B) ratio for TSVT in comparison with other companies in the Drug Manufacturers - General industry. Currently, TSVT has a P/B value of 1.2. This P/B ratio is low compared to industry peers. It might indicate the stock is undervalued or that the company’s assets are not expected to generate strong returns.

Income Statement



TTM
Revenue

Total Revenue

Cost Of Revenue

Gross Profit

Operating Expenses

Selling, General & Admin Expenses

R&D Expenses

Depreciation And Amortization

Total Operating Expenses

Income

Income Before Tax

Operating Income

EBITDA

EBIT

Earnings From Continuing Operations

Net Income

Income Tax Expense

Other Non-Operating Income (Expenses)

Extraordinary Items

Discontinued Operations

Effect Of Accounting Charges

Non Recurring

Minority Interest

Other Items

Interest Income

Interest Expense

Net Interest Income

Values in undefined except per share items