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TSVT vs. VOO
Performance
Risk-Adjusted Performance
Dividends
Drawdowns
Volatility

Correlation

The correlation between TSVT and VOO is 0.33, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.


Performance

TSVT vs. VOO - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in 2seventy bio, Inc. (TSVT) and Vanguard S&P 500 ETF (VOO). The values are adjusted to include any dividend payments, if applicable.

-80.00%-60.00%-40.00%-20.00%0.00%20.00%40.00%December2025FebruaryMarchAprilMay
-63.69%
28.14%
TSVT
VOO

Key characteristics

Sharpe Ratio

TSVT:

0.12

VOO:

0.56

Sortino Ratio

TSVT:

0.89

VOO:

0.92

Omega Ratio

TSVT:

1.11

VOO:

1.13

Calmar Ratio

TSVT:

0.01

VOO:

0.58

Martin Ratio

TSVT:

0.04

VOO:

2.25

Ulcer Index

TSVT:

26.44%

VOO:

4.83%

Daily Std Dev

TSVT:

100.96%

VOO:

19.11%

Max Drawdown

TSVT:

-96.31%

VOO:

-33.99%

Current Drawdown

TSVT:

-88.25%

VOO:

-7.55%

Returns By Period

In the year-to-date period, TSVT achieves a 70.07% return, which is significantly higher than VOO's -3.28% return.


TSVT

YTD

70.07%

1M

2.25%

6M

-0.20%

1Y

11.61%

5Y*

N/A

10Y*

N/A

VOO

YTD

-3.28%

1M

13.71%

6M

-4.52%

1Y

10.70%

5Y*

15.89%

10Y*

12.40%

*Annualized

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Risk-Adjusted Performance

TSVT vs. VOO — Risk-Adjusted Performance Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

TSVT
The Risk-Adjusted Performance Rank of TSVT is 5757
Overall Rank
The Sharpe Ratio Rank of TSVT is 5757
Sharpe Ratio Rank
The Sortino Ratio Rank of TSVT is 6363
Sortino Ratio Rank
The Omega Ratio Rank of TSVT is 6060
Omega Ratio Rank
The Calmar Ratio Rank of TSVT is 5252
Calmar Ratio Rank
The Martin Ratio Rank of TSVT is 5252
Martin Ratio Rank

VOO
The Risk-Adjusted Performance Rank of VOO is 6464
Overall Rank
The Sharpe Ratio Rank of VOO is 6161
Sharpe Ratio Rank
The Sortino Ratio Rank of VOO is 6262
Sortino Ratio Rank
The Omega Ratio Rank of VOO is 6464
Omega Ratio Rank
The Calmar Ratio Rank of VOO is 6767
Calmar Ratio Rank
The Martin Ratio Rank of VOO is 6464
Martin Ratio Rank
The risk-adjusted ranks indicate the investment's position relative to the market. A rank closer to 100 signifies top-performing investments, while a rank closer to 0 might suggest underperformance, based on the selected ratio. The values are calculated based on the past 12 months of returns.

TSVT vs. VOO - Risk-Adjusted Performance Comparison

This table presents a comparison of risk-adjusted performance metrics for 2seventy bio, Inc. (TSVT) and Vanguard S&P 500 ETF (VOO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.


The current TSVT Sharpe Ratio is 0.12, which is lower than the VOO Sharpe Ratio of 0.56. The chart below compares the historical Sharpe Ratios of TSVT and VOO, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.


Rolling 12-month Sharpe Ratio-1.000.001.002.003.00December2025FebruaryMarchAprilMay
0.12
0.56
TSVT
VOO

Dividends

TSVT vs. VOO - Dividend Comparison

TSVT has not paid dividends to shareholders, while VOO's dividend yield for the trailing twelve months is around 1.34%.


TTM20242023202220212020201920182017201620152014
TSVT
2seventy bio, Inc.
0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%
VOO
Vanguard S&P 500 ETF
1.34%1.24%1.46%1.69%1.25%1.54%1.88%2.06%1.78%2.02%2.10%1.85%

Drawdowns

TSVT vs. VOO - Drawdown Comparison

The maximum TSVT drawdown since its inception was -96.31%, which is greater than VOO's maximum drawdown of -33.99%. Use the drawdown chart below to compare losses from any high point for TSVT and VOO. For additional features, visit the drawdowns tool.


-100.00%-80.00%-60.00%-40.00%-20.00%0.00%December2025FebruaryMarchAprilMay
-88.25%
-7.55%
TSVT
VOO

Volatility

TSVT vs. VOO - Volatility Comparison

The current volatility for 2seventy bio, Inc. (TSVT) is 1.23%, while Vanguard S&P 500 ETF (VOO) has a volatility of 11.03%. This indicates that TSVT experiences smaller price fluctuations and is considered to be less risky than VOO based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


0.00%10.00%20.00%30.00%40.00%50.00%60.00%December2025FebruaryMarchAprilMay
1.23%
11.03%
TSVT
VOO