Rezolute, Inc. (RZLT)

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Rezolute, Inc. (RZLT) is up 101.3% since the beginning of the year. At $5 per share, RZLT is trading 58.5% below its 52-week high of $11. Investors who bought $1,000 worth of RZLT shares 5 years ago would now be looking at an investment worth $439.

Rezolute, Inc. (RZLT) has returned 101.27% so far this year and -9.70% over the past 12 months. Over the last ten years, RZLT has returned -20.14% per year, falling short of the S&P 500 Index benchmark, which averaged 13.41% annually.

Based on dividend-adjusted daily data since May 1, 2014, RZLT's average daily return is +0.33%, while the average monthly return is +2.01%. At this rate, an investment would double in approximately 2.9 years.

Historically, 43% of months were positive and 57% were negative. The best month was Jul 2020 with a return of +269.9%, while the worst month was Dec 2025 at -75.7%. The longest winning streak lasted 11 consecutive months, and the longest losing streak was 8 months.

On a daily basis, RZLT closed higher 36% of trading days. The best single day was Jan 7, 2019 with a return of +250.0%, while the worst single day was Dec 11, 2025 at -87.2%.

Rezolute, Inc. has an annualized alpha of 115.20%, beta of 0.56, and R2 of 0.00 versus S&P 500 Index. Calculated based on daily prices since May 01, 2014.

• This stock participated in 215.13% of S&P 500 Index downside but only 54.58% of its upside - more exposed to losses than it benefited from rallies.
• Beta of 0.56 may look defensive, but with R2 of 0.00 this stock is largely uncorrelated with S&P 500 Index - low beta reflects independence, not downside protection. See the Volatility section for a true picture of this stock's risk.
• R2 of 0.00 means this stock moves largely independently of S&P 500 Index - capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.

RZLT ranks 56 for risk / return — on par with similar stocks. You're getting a typical balance of risk and reward. Not a standout, but not a red flag either — a reasonable choice if other factors align with your goals.

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.

The table below displays the maximum drawdowns of the Rezolute, Inc.. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the Rezolute, Inc. was 99.63%, occurring on Nov 29, 2023. The portfolio has not yet recovered.

The current Rezolute, Inc. drawdown is 97.63%.

The chart below shows the rolling one-month volatility.

The chart below illustrates the trends in the financial health of Rezolute, Inc. over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.

The Valuation section provides an overview of how Rezolute, Inc. is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.