Rezolute, Inc. (RZLT)

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The chart shows the growth of an initial investment of $10,000 in Rezolute, Inc., comparing it to the performance of the S&P 500 index or another benchmark. All prices have been adjusted for splits and dividends.

Rezolute, Inc. (RZLT) has returned 29.24% so far this year and 5.17% over the past 12 months. Over the last ten years, RZLT has returned -25.45% per year, falling short of the S&P 500 Index benchmark, which averaged 12.16% annually.

Based on dividend-adjusted daily data since May 1, 2014, RZLT's average daily return is +0.32%, while the average monthly return is +1.67%. At this rate, your investment would double in approximately 3.5 years.

Historically, 41% of months were positive and 59% were negative. The best month was Jul 2020 with a return of +269.9%, while the worst month was Dec 2025 at -75.7%. The longest winning streak lasted 11 consecutive months, and the longest losing streak was 8 months.

On a daily basis, RZLT closed higher 36% of trading days. The best single day was Jan 7, 2019 with a return of +250.0%, while the worst single day was Dec 11, 2025 at -87.2%.

Rezolute, Inc. has an annualized alpha of 111.84%, beta of 0.55, and R² of 0.00 versus S&P 500 Index. Calculated based on daily prices since May 02, 2014.

• This stock participated in 222.45% of S&P 500 Index downside but only 58.38% of its upside — more exposed to losses than it benefited from rallies.
• Beta of 0.55 may look defensive, but with R² of 0.00 this stock is largely uncorrelated with S&P 500 Index — low beta reflects independence, not downside protection. See the Volatility section for a true picture of this stock's risk.
• R² of 0.00 means this stock moves largely independently of S&P 500 Index — capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.

RZLT ranks 56 for risk / return — on par with similar stocks. You're getting a typical balance of risk and reward. Not a standout, but not a red flag either — a reasonable choice if other factors align with your goals.

The table below present risk-adjusted performance metrics for Rezolute, Inc. (RZLT) and compare them to a chosen benchmark (S&P 500 Index).

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.

The table below displays the maximum drawdowns of the Rezolute, Inc.. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the Rezolute, Inc. was 99.63%, occurring on Nov 29, 2023. The portfolio has not yet recovered.

The current Rezolute, Inc. drawdown is 98.48%.

The chart below shows the rolling one-month volatility.

The chart below illustrates the trends in the financial health of Rezolute, Inc. over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.

The Valuation section provides an overview of how Rezolute, Inc. is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.