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Cortexyme Inc (QNCX)
Performance
Return for Risk
Dividends
Drawdowns
Volatility
Financials

Company Info

IPO Date
May 9, 2019

Highlights

Market Cap
$5.47M
Enterprise Value
$34.65M
EPS (TTM)
-$1.13
Gross Profit (TTM)
-$87.00K
EBITDA (TTM)
-$54.74M
Year Range
$0.08 - $4.55
ROA (TTM)
-51.85%
ROE (TTM)
-5,380.45%

Share Price Chart


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Cortexyme Inc

Often compared with QNCX:
QNCX vs. DAL

Performance

Performance Chart

The chart shows the growth of an initial investment of $10,000 in Cortexyme Inc, comparing it to the performance of the S&P 500 index or another benchmark. All prices have been adjusted for splits and dividends.


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S&P 500 Index

Returns By Period

Cortexyme Inc (QNCX) has returned -96.97% so far this year and -92.38% over the past 12 months.


Cortexyme Inc

1D
0.10%
1M
-19.33%
YTD
-96.97%
6M
-93.78%
1Y
-92.38%
3Y*
-59.79%
5Y*
-69.33%
10Y*

Benchmark (S&P 500 Index)

1D
2.91%
1M
-5.09%
YTD
-4.63%
6M
-2.39%
1Y
16.33%
3Y*
16.69%
5Y*
10.18%
10Y*
12.16%
*Multi-year figures are annualized to reflect compound growth (CAGR)

Monthly Returns

Based on dividend-adjusted daily data since May 9, 2019, QNCX's average daily return is +0.09%, while the average monthly return is +0.84%. At this rate, your investment would double in approximately 6.9 years.

Historically, 42% of months were positive and 58% were negative. The best month was Nov 2025 with a return of +121.2%, while the worst month was Jan 2026 at -94.9%. The longest winning streak lasted 6 consecutive months, and the longest losing streak was 9 months.

On a daily basis, QNCX closed higher 46% of trading days. The best single day was Feb 10, 2026 with a return of +306.2%, while the worst single day was Jan 29, 2026 at -91.5%.


JanFebMarAprMayJunJulAugSepOctNovDecTotal
2026-94.93%-26.06%-19.33%-96.97%
2025-13.90%-9.94%-8.28%-17.29%-5.45%58.65%2.42%-5.33%1.87%1.23%121.21%-8.22%79.14%
202418.10%4.84%-18.46%0.94%-22.43%-9.64%-0.01%-7.85%12.33%108.71%26.54%-8.78%78.10%
202353.75%-5.35%68.18%-1.92%-1.96%0.33%-20.27%9.17%-14.50%-13.34%-8.30%17.98%64.73%
2022-51.82%-28.45%42.30%-40.87%-29.23%-14.29%-12.16%-9.74%-24.43%-24.81%-26.30%-13.51%-94.95%
202141.18%-13.13%5.75%8.71%5.62%28.11%6.62%70.41%-4.82%-85.60%-1.44%-3.00%-54.57%

Benchmark Metrics

Cortexyme Inc has an annualized alpha of 10.06%, beta of 0.94, and R² of 0.01 versus S&P 500 Index. Calculated based on daily prices since May 10, 2019.

  • This stock participated in 195.47% of S&P 500 Index downside but only -67.58% of its upside — more exposed to losses than it benefited from rallies.
  • R² of 0.01 means this stock moves largely independently of S&P 500 Index — capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.

Alpha
10.06%
Beta
0.94
0.01
Upside Capture
-67.58%
Downside Capture
195.47%

Return for Risk

Risk / Return Rank

QNCX ranks 33 for risk / return — below 33% of stocks on our site. The returns aren't fully compensating for the risk involved. This isn't necessarily a dealbreaker, but factor it into your decision — especially if you're risk-averse.


QNCX Risk / Return Rank: 3333
Overall Rank
QNCX Sharpe Ratio Rank: 2828
Sharpe Ratio Rank
QNCX Sortino Ratio Rank: 6060
Sortino Ratio Rank
QNCX Omega Ratio Rank: 7070
Omega Ratio Rank
QNCX Calmar Ratio Rank: 55
Calmar Ratio Rank
QNCX Martin Ratio Rank: 11
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

Return / Risk — by metrics

The table below present risk-adjusted performance metrics for Cortexyme Inc (QNCX) and compare them to a chosen benchmark (S&P 500 Index).


QNCXBenchmarkDifference

Sharpe ratio

Return per unit of total volatility

-0.27

0.90

-1.16

Sortino ratio

Return per unit of downside risk

1.20

1.39

-0.19

Omega ratio

Gain probability vs. loss probability

1.22

1.21

+0.01

Calmar ratio

Return relative to maximum drawdown

-0.94

1.40

-2.34

Martin ratio

Return relative to average drawdown

-2.16

6.61

-8.77

Explore QNCX risk-adjusted metrics in detail

Dive deeper into individual metrics with historical trends, benchmark comparisons, and performance across different time periods.

Dividends

Dividend History


Cortexyme Inc doesn't pay dividends

Drawdowns

Drawdowns Chart

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.


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Worst Drawdowns

The table below displays the maximum drawdowns of the Cortexyme Inc. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the Cortexyme Inc was 99.93%, occurring on Mar 20, 2026. The portfolio has not yet recovered.

The current Cortexyme Inc drawdown is 99.92%.


Depth

Start

To Bottom

Bottom

To Recover

End

Total

-99.93%Aug 11, 20211157Mar 20, 2026
-61.69%Feb 18, 2020222Dec 31, 2020151Aug 9, 2021373
-56.16%Jul 2, 201943Aug 30, 201977Dec 19, 2019120
-38.11%Dec 24, 20199Jan 7, 202027Feb 14, 202036
-27.46%May 10, 20191May 10, 201925Jun 17, 201926

Volatility

Volatility Chart

The chart below shows the rolling one-month volatility.


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Financials

Financial Performance

The chart below illustrates the trends in the financial health of Cortexyme Inc over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.


Annual
Quarterly

0.0

Valuation

The Valuation section provides an overview of how Cortexyme Inc is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.


PB Ratio

The chart illustrates the Price-to-Book (P/B) ratio for QNCX in comparison with other companies in the Biotechnology industry. Currently, QNCX has a P/B value of 5.2. This P/B ratio is in line with the industry average, suggesting the stock is valued fairly in relation to its book value.

Income Statement



TTM
Revenue

Total Revenue

Cost Of Revenue

Gross Profit

Operating Expenses

Selling, General & Admin Expenses

R&D Expenses

Depreciation And Amortization

Total Operating Expenses

Income

Income Before Tax

Operating Income

EBITDA

EBIT

Earnings From Continuing Operations

Net Income

Income Tax Expense

Other Non-Operating Income (Expenses)

Extraordinary Items

Discontinued Operations

Effect Of Accounting Charges

Non Recurring

Minority Interest

Other Items

Interest Income

Interest Expense

Net Interest Income

Values in undefined except per share items