QNCX vs. DAL

Last updated Jul 11, 2026

QNCX (Cortexyme Inc) and DAL (Delta Air Lines, Inc.) are both stocks. QNCX operates in Biotechnology (Healthcare), while DAL operates in Airlines (Industrials). Over the past 5 years, QNCX returned -72.66%/yr vs 16.10%/yr for DAL. At a 0.14 correlation, their price movements are largely independent.

Performance

QNCX vs. DAL - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Cortexyme Inc (QNCX) and Delta Air Lines, Inc. (DAL). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, QNCX achieves a -97.38% return, which is significantly lower than DAL's 26.91% return.

QNCX

• 1D: 0.29%
• 1M: -6.07%
• 6M: -96.74%
• YTD: -97.38%
• 1Y: -95.18%
• 3Y*: -61.36%
• 5Y*: -72.66%
• 10Y*: —

DAL

• 1D: -1.81%
• 1M: 5.47%
• 6M: 21.80%
• YTD: 26.91%
• 1Y: 56.49%
• 3Y*: 22.99%
• 5Y*: 16.10%
• 10Y*: 9.43%

*Multi-year figures are annualized to reflect compound growth (CAGR)

QNCX vs. DAL - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019
QNCX Cortexyme Inc	-97.38%	79.14%	78.10%	64.73%	-94.95%	-54.57%	-50.52%	178.33%
DAL Delta Air Lines, Inc.	26.91%	16.09%	52.00%	23.03%	-15.92%	-2.81%	-30.77%	5.03%

Correlation

The correlation between QNCX and DAL is 0.14, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.14
Correlation (3Y) Calculated over the trailing 3-year period	0.07
Correlation (5Y) Calculated over the trailing 5-year period	0.15
Correlation (All Time) Calculated using the full available price history since May 9, 2019	0.14

Fundamentals

Market Cap QNCX : $4.88M DAL : $57.41B
EPS QNCX : -$1.61 DAL : $6.04
Total Revenue (TTM) QNCX : $0.00 DAL : $68.29B
Gross Profit (TTM) QNCX : -$71.00K DAL : $18.66B
EBITDA (TTM) QNCX : -$58.07M DAL : $8.42B

Return for Risk

QNCX vs. DAL — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

QNCX

QNCX Risk / Return Rank: 35
QNCX Sharpe Ratio Rank: 33
QNCX Sortino Ratio Rank: 61
QNCX Omega Ratio Rank: 69
QNCX Calmar Ratio Rank: 3
QNCX Martin Ratio Rank: 8

DAL

DAL Risk / Return Rank: 83
DAL Sharpe Ratio Rank: 84
DAL Sortino Ratio Rank: 82
DAL Omega Ratio Rank: 78
DAL Calmar Ratio Rank: 83
DAL Martin Ratio Rank: 87

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

QNCX vs. DAL - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Cortexyme Inc (QNCX) and Delta Air Lines, Inc. (DAL). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	QNCX	DAL	Difference
Sharpe ratio: Return per unit of total volatility	-0.27	1.42	-1.68
Sortino ratio: Return per unit of downside risk	1.06	2.20	-1.14
Omega ratio: Gain probability vs. loss probability	1.19	1.25	-0.06
Calmar ratio: Return relative to maximum drawdown	-0.97	2.46	-3.43
Martin ratio: Return relative to average drawdown	-1.44	7.83	-9.27

QNCX vs. DAL - Sharpe Ratio Comparison

The current QNCX Sharpe Ratio is -0.27, which is lower than the DAL Sharpe Ratio of 1.42. The chart below compares the historical Sharpe Ratios of QNCX and DAL, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

QNCX vs. DAL - Drawdown Comparison

The maximum QNCX drawdown since its inception was -99.93%, which is greater than DAL's maximum drawdown of -81.93%. Use the drawdown chart below to compare losses from any high point for QNCX and DAL.

Drawdown Indicators

	QNCX	DAL	Difference
Max Drawdown Largest peak-to-trough decline	-99.93%	-81.93%	-18.00%
Max Drawdown (1Y) Largest decline over 1 year	-98.18%	-22.90%	-75.28%
Max Drawdown (3Y) Largest decline over 3 years	-98.18%	-47.92%	-50.26%
Max Drawdown (5Y) Largest decline over 5 years	-99.93%	-47.92%	-52.01%
Max Drawdown (10Y) Largest decline over 10 years	—	-69.18%	—
Current Drawdown Current decline from peak	-99.93%	-6.46%	-93.47%
Average Drawdown Average peak-to-trough decline	-76.42%	-29.02%	-47.40%
Ulcer Index Depth and duration of drawdowns from previous peaks	65.94%	7.19%	+58.75%

Volatility

QNCX vs. DAL - Volatility Comparison

Cortexyme Inc (QNCX) has a higher volatility of 15.46% compared to Delta Air Lines, Inc. (DAL) at 12.21%. This indicates that QNCX's price experiences larger fluctuations and is considered to be riskier than DAL based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	QNCX	DAL	Difference
Volatility (1M) Calculated over the trailing 1-month period	15.46%	12.21%	+3.25%
Volatility (6M) Calculated over the trailing 6-month period	322.28%	30.37%	+291.91%
Volatility (1Y) Calculated over the trailing 1-year period	355.33%	41.55%	+313.78%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	182.37%	41.03%	+141.34%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	162.98%	42.10%	+120.88%

Dividends

QNCX vs. DAL - Dividend Comparison

QNCX has not paid dividends to shareholders, while DAL's dividend yield for the trailing twelve months is around 1.10%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
DAL Delta Air Lines, Inc.	1.10%	0.97%	0.83%	0.50%	0.00%	0.00%	1.00%	2.57%	2.63%	1.81%	1.37%	0.89%
QNCX Cortexyme Inc	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Financials

Frequently Asked Questions

Can I hold both QNCX and DAL in my portfolio?

QNCX and DAL have a correlation of 0.14, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, QNCX or DAL?

QNCX has higher volatility (15.46%) compared to DAL (12.21%). In terms of maximum drawdown, QNCX dropped -99.93% vs DAL's -81.93%.

Which has better risk-adjusted returns?

DAL currently has the higher Sharpe Ratio (1.42 vs -0.27), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.