- ISIN
- NL0010872495
- CUSIP
- 001087249
- Sector
- Healthcare
- Industry
- Biotechnology
- IPO Date
- Sep 18, 2014
Highlights
- Market Cap
- $181.13M
- Enterprise Value
- $108.66M
- EPS (TTM)
- -€0.43
- Total Revenue (TTM)
- €13.44M
- Gross Profit (TTM)
- €12.06M
- EBITDA (TTM)
- -€43.44M
- Year Range
- $1.33 - $3.10
- Target Price
- $3.63
- ROA (TTM)
- -46.02%
- ROE (TTM)
- -121.22%
- Avg. Volume (1M)
- 1M
- Avg. Volume Value (1M)
- $1.78M
Share Price Chart
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Performance
PRQR Performance Chart
ProQR Therapeutics N.V. (PRQR) is down 14.9% since the beginning of the year. At $2 per share, PRQR is trading 44.5% below its 52-week high of $3. Investors who bought $1,000 worth of PRQR shares 5 years ago would now be looking at an investment worth $329.
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Returns By Period
ProQR Therapeutics N.V. (PRQR) has returned -14.85% so far this year and -17.31% over the past 12 months. Over the last ten years, PRQR has returned -10.12% per year, falling short of the S&P 500 Index benchmark, which averaged 13.26% annually.
ProQR Therapeutics N.V.
- 1D
- -3.37%
- 1M
- -4.97%
- 6M
- 6.17%
- YTD
- -14.85%
- 1Y
- -17.31%
- 3Y*
- 2.23%
- 5Y*
- -19.94%
- 10Y*
- -10.12%
- ALL TIME*
- -18.64%
Benchmark (S&P 500 Index)
- 1D
- 0.70%
- 1M
- 0.09%
- 6M
- 7.94%
- YTD
- 9.41%
- 1Y
- 20.07%
- 3Y*
- 17.84%
- 5Y*
- 11.25%
- 10Y*
- 13.26%
- ALL TIME*
- 8.09%
PRQR Monthly Returns History
Based on dividend-adjusted daily data since Sep 18, 2014, PRQR's average daily return is +0.08%, while the average monthly return is +1.65%. At this rate, an investment would double in approximately 3.5 years.
Historically, 47% of months were positive and 53% were negative. The best month was Dec 2022 with a return of +200.8%, while the worst month was Feb 2022 at -80.4%. The longest winning streak lasted 4 consecutive months, and the longest losing streak was 5 months.
On a daily basis, PRQR closed higher 45% of trading days. The best single day was Oct 16, 2024 with a return of +122.1%, while the worst single day was Feb 11, 2022 at -75.4%.
| Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec | Total | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026 | -19.80% | -1.85% | 1.89% | -3.09% | 0.64% | 17.72% | -7.53% | -14.85% | |||||
| 2025 | -20.19% | 10.17% | -42.92% | 24.81% | -0.00% | 22.89% | 2.94% | 7.14% | -5.33% | 29.11% | -14.91% | -13.68% | -23.77% |
| 2024 | 9.60% | -7.14% | 13.64% | -15.28% | 0.52% | -14.87% | 16.27% | 4.66% | -9.90% | 92.31% | 9.71% | -30.99% | 33.84% |
| 2023 | -25.41% | 6.88% | -27.80% | 2.35% | -20.18% | -6.90% | -7.41% | 7.00% | -19.00% | -11.54% | 34.78% | 27.74% | -46.49% |
| 2022 | -31.96% | -80.37% | -15.40% | -23.44% | -4.76% | 17.83% | 7.70% | -5.69% | -5.81% | 24.34% | 32.96% | 200.81% | -53.81% |
| 2021 | 10.48% | -1.51% | 44.64% | -5.90% | 0.32% | 8.01% | -22.40% | 27.72% | 25.30% | -7.77% | -8.55% | 13.46% | 90.71% |
Benchmark Metrics
ProQR Therapeutics N.V. has an annualized alpha of 8.46%, beta of 1.01, and R2 of 0.04 versus S&P 500 Index. Calculated based on daily prices since September 18, 2014.
- This stock participated in 157.99% of S&P 500 Index downside but only 23.92% of its upside - more exposed to losses than it benefited from rallies.
- R2 of 0.04 means this stock moves largely independently of S&P 500 Index - capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.
- Alpha
- 8.46%
- Beta
- 1.01
- R²
- 0.04
- Upside Capture
- 23.92%
- Downside Capture
- 157.99%
Return for Risk
Risk / Return Rank
PRQR ranks 35 for risk / return — above 35% of stocks peers on PortfoliosLab. Its historical combined result is below the peer median.
Risk / Return Metrics
The table below present risk-adjusted performance metrics for ProQR Therapeutics N.V. (PRQR) and compare them to S&P 500 Index.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| PRQR | Benchmark | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -1.65 | ||
| Sortino ratioReturn per unit of downside risk | -1.80 | ||
| Omega ratioGain probability vs. loss probability | 1.02 | 1.25 | -0.23 |
| Calmar ratioReturn relative to maximum drawdown | -0.33 | 2.00 | -2.33 |
| Martin ratioReturn relative to average drawdown | -0.49 | 8.49 | -8.98 |
Dividends
Dividend History
Drawdowns
Drawdowns Chart
The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.
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Worst Drawdowns
The table below displays the maximum drawdowns of the ProQR Therapeutics N.V.. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.
The maximum drawdown for the ProQR Therapeutics N.V. was 97.76%, occurring on May 11, 2022. The portfolio has not yet recovered.
The current ProQR Therapeutics N.V. drawdown is 93.12%.
Drawdown | Fall | Recovery | Underwater | Related event |
|---|---|---|---|---|
-97.76%May 2022 | 7y 2mo | — | 11y 4moMar 2015 - now | Bear market2022 |
-42.51%Nov 2014 | 1mo 20d | 1mo 12d | 3mo 2dSep 2014 - Dec 2014 | — |
-26.90%Feb 2015 | 1mo 3d | 1mo | 2mo 3dJan 2015 - Mar 2015 | — |
-6.67%Dec 2014 | 4d | 4d | 8dDec 2014 - Dec 2014 | — |
Drawdown Indicators
| PRQR | Benchmark | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -97.76% | -56.78% | -40.98% |
Max Drawdown (1Y)Largest decline over 1 year | -55.08% | -9.10% | -45.98% |
Max Drawdown (3Y)Largest decline over 3 years | -75.06% | -18.90% | -56.16% |
Max Drawdown (5Y)Largest decline over 5 years | -93.39% | -25.43% | -67.96% |
Max Drawdown (10Y)Largest decline over 10 years | -97.50% | -33.92% | -63.58% |
Current DrawdownCurrent decline from peak | -93.12% | -1.58% | -91.54% |
Average DrawdownAverage peak-to-trough decline | -75.17% | -10.70% | -64.47% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 36.97% | 2.14% | +34.83% |
Volatility
Volatility Chart
The chart below shows the rolling one-month volatility.
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Financials
Financial Performance
The chart below illustrates the trends in the financial health of ProQR Therapeutics N.V. over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.
Valuation
The Valuation section provides an overview of how ProQR Therapeutics N.V. is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.
PS Ratio
This chart shows the Price-to-Sales (P/S) ratio for PRQR relative to other companies in the Biotechnology industry. Currently, PRQR has a P/S ratio of 11.8. This P/S ratio falls within the average range for the industry, suggesting the stock is fairly valued based on its revenue.
PB Ratio
The chart illustrates the Price-to-Book (P/B) ratio for PRQR in comparison with other companies in the Biotechnology industry. Currently, PRQR has a P/B value of 4.2. This P/B ratio is in line with the industry average, suggesting the stock is valued fairly in relation to its book value.
Income Statement
| TTM | |
|---|---|
Revenue | |
Total Revenue | — |
Cost Of Revenue | — |
Gross Profit | — |
Operating Expenses | |
Selling, General & Admin Expenses | — |
R&D Expenses | — |
Depreciation And Amortization | — |
Total Operating Expenses | — |
Income | |
Income Before Tax | — |
Operating Income | — |
EBITDA | — |
EBIT | — |
Earnings From Continuing Operations | — |
Net Income | — |
Income Tax Expense | — |
Other Non-Operating Income (Expenses) | — |
Extraordinary Items | — |
Discontinued Operations | — |
Effect Of Accounting Charges | — |
Non Recurring | — |
Minority Interest | — |
Other Items | — |
Interest Income | — |
Interest Expense | — |
Net Interest Income | — |
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