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ProQR Therapeutics N.V. (PRQR)
Performance
Return for Risk
Dividends
Drawdowns
Volatility
Financials

Company Info

ISIN
NL0010872495
CUSIP
001087249
IPO Date
Sep 18, 2014

Highlights

Market Cap
$166.88M
Enterprise Value
$92.93M
EPS (TTM)
-$0.40
Total Revenue (TTM)
$15.90M
Gross Profit (TTM)
$15.22M
EBITDA (TTM)
-$40.41M
Year Range
$1.07 - $3.10
Target Price
$3.63
ROA (TTM)
-37.35%
ROE (TTM)
-85.30%

Share Price Chart


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ProQR Therapeutics N.V.

Performance

Performance Chart

The chart shows the growth of an initial investment of $10,000 in ProQR Therapeutics N.V., comparing it to the performance of the S&P 500 index or another benchmark. All prices have been adjusted for splits and dividends.


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S&P 500 Index

Returns By Period

ProQR Therapeutics N.V. (PRQR) has returned -19.80% so far this year and 21.80% over the past 12 months. Over the last ten years, PRQR has returned -10.62% per year, falling short of the S&P 500 Index benchmark, which averaged 12.16% annually.


ProQR Therapeutics N.V.

1D
7.28%
1M
1.89%
YTD
-19.80%
6M
-23.94%
1Y
21.80%
3Y*
-8.72%
5Y*
-24.35%
10Y*
-10.62%

Benchmark (S&P 500 Index)

1D
2.91%
1M
-5.09%
YTD
-4.63%
6M
-2.39%
1Y
16.33%
3Y*
16.69%
5Y*
10.18%
10Y*
12.16%
*Multi-year figures are annualized to reflect compound growth (CAGR)

Monthly Returns

Based on dividend-adjusted daily data since Sep 18, 2014, PRQR's average daily return is +0.09%, while the average monthly return is +1.86%. At this rate, your investment would double in approximately 3.1 years.

Historically, 47% of months were positive and 53% were negative. The best month was Dec 2022 with a return of +200.8%, while the worst month was Feb 2022 at -80.4%. The longest winning streak lasted 4 consecutive months, and the longest losing streak was 5 months.

On a daily basis, PRQR closed higher 45% of trading days. The best single day was Oct 16, 2024 with a return of +122.1%, while the worst single day was Feb 11, 2022 at -75.4%.


JanFebMarAprMayJunJulAugSepOctNovDecTotal
2026-19.80%-1.85%1.89%-19.80%
2025-20.19%10.17%-42.92%24.81%-0.00%22.89%2.94%7.14%-5.33%29.11%-14.91%-13.68%-23.77%
20249.60%-7.14%13.64%-15.28%0.52%-14.87%16.27%4.66%-9.90%92.31%9.71%-30.99%33.84%
2023-25.41%6.88%-27.80%2.35%-20.18%-6.90%-7.41%7.00%-19.00%-11.54%34.78%27.74%-46.49%
2022-31.96%-80.37%-15.40%-23.44%-4.76%17.83%7.70%-5.69%-5.81%24.34%32.96%200.81%-53.81%
202110.48%-1.51%44.64%-5.90%0.32%8.01%-22.40%27.72%25.30%-7.77%-8.55%13.46%90.71%

Benchmark Metrics

ProQR Therapeutics N.V. has an annualized alpha of 11.22%, beta of 0.99, and R² of 0.03 versus S&P 500 Index. Calculated based on daily prices since September 19, 2014.

  • This stock participated in 150.74% of S&P 500 Index downside but only 26.09% of its upside — more exposed to losses than it benefited from rallies.
  • R² of 0.03 means this stock moves largely independently of S&P 500 Index — capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.

Alpha
11.22%
Beta
0.99
0.03
Upside Capture
26.09%
Downside Capture
150.74%

Return for Risk

Risk / Return Rank

PRQR ranks 50 for risk / return — on par with similar stocks. You're getting a typical balance of risk and reward. Not a standout, but not a red flag either — a reasonable choice if other factors align with your goals.


PRQR Risk / Return Rank: 5050
Overall Rank
PRQR Sharpe Ratio Rank: 5151
Sharpe Ratio Rank
PRQR Sortino Ratio Rank: 5353
Sortino Ratio Rank
PRQR Omega Ratio Rank: 5050
Omega Ratio Rank
PRQR Calmar Ratio Rank: 4747
Calmar Ratio Rank
PRQR Martin Ratio Rank: 4747
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

Return / Risk — by metrics

The table below present risk-adjusted performance metrics for ProQR Therapeutics N.V. (PRQR) and compare them to a chosen benchmark (S&P 500 Index).


PRQRBenchmarkDifference

Sharpe ratio

Return per unit of total volatility

0.30

0.90

-0.60

Sortino ratio

Return per unit of downside risk

0.95

1.39

-0.44

Omega ratio

Gain probability vs. loss probability

1.11

1.21

-0.10

Calmar ratio

Return relative to maximum drawdown

0.29

1.40

-1.11

Martin ratio

Return relative to average drawdown

0.58

6.61

-6.03

Explore PRQR risk-adjusted metrics in detail

Dive deeper into individual metrics with historical trends, benchmark comparisons, and performance across different time periods.

Dividends

Dividend History


ProQR Therapeutics N.V. doesn't pay dividends

Drawdowns

Drawdowns Chart

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.


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Worst Drawdowns

The table below displays the maximum drawdowns of the ProQR Therapeutics N.V.. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the ProQR Therapeutics N.V. was 97.76%, occurring on May 11, 2022. The portfolio has not yet recovered.

The current ProQR Therapeutics N.V. drawdown is 93.52%.


Depth

Start

To Bottom

Bottom

To Recover

End

Total

-97.76%Mar 11, 20151807May 11, 2022
-33.45%Oct 1, 201428Nov 7, 201419Dec 5, 201447
-26.9%Jan 2, 201523Feb 4, 201521Mar 6, 201544
-9.9%Dec 15, 20141Dec 15, 20144Dec 19, 20145
-6.67%Dec 22, 20144Dec 26, 20142Dec 30, 20146

Volatility

Volatility Chart

The chart below shows the rolling one-month volatility.


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Financials

Financial Performance

The chart below illustrates the trends in the financial health of ProQR Therapeutics N.V. over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.


Annual
Quarterly

0.0

Valuation

The Valuation section provides an overview of how ProQR Therapeutics N.V. is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.


PS Ratio

This chart shows the Price-to-Sales (P/S) ratio for PRQR relative to other companies in the Biotechnology industry. Currently, PRQR has a P/S ratio of 10.8. This P/S ratio falls within the average range for the industry, suggesting the stock is fairly valued based on its revenue.

PB Ratio

The chart illustrates the Price-to-Book (P/B) ratio for PRQR in comparison with other companies in the Biotechnology industry. Currently, PRQR has a P/B value of 3.4. This P/B ratio is in line with the industry average, suggesting the stock is valued fairly in relation to its book value.

Income Statement



TTM
Revenue

Total Revenue

Cost Of Revenue

Gross Profit

Operating Expenses

Selling, General & Admin Expenses

R&D Expenses

Depreciation And Amortization

Total Operating Expenses

Income

Income Before Tax

Operating Income

EBITDA

EBIT

Earnings From Continuing Operations

Net Income

Income Tax Expense

Other Non-Operating Income (Expenses)

Extraordinary Items

Discontinued Operations

Effect Of Accounting Charges

Non Recurring

Minority Interest

Other Items

Interest Income

Interest Expense

Net Interest Income

Values in undefined except per share items