CASI Pharmaceuticals, Inc. (CASI)

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The chart shows the growth of an initial investment of $10,000 in CASI Pharmaceuticals, Inc., comparing it to the performance of the S&P 500 index or another benchmark. All prices have been adjusted for splits and dividends.

CASI Pharmaceuticals, Inc. (CASI) has returned -75.59% so far this year and -90.39% over the past 12 months. Over the last ten years, CASI has returned -32.65% per year, falling short of the S&P 500 Index benchmark, which averaged 12.16% annually.

Based on dividend-adjusted daily data since Jun 12, 1996, CASI's average daily return is +0.11%, while the average monthly return is +1.04%. At this rate, your investment would double in approximately 5.6 years.

Historically, 39% of months were positive and 61% were negative. The best month was Feb 2000 with a return of +151.0%, while the worst month was Feb 2026 at -79.7%. The longest winning streak lasted 5 consecutive months, and the longest losing streak was 11 months.

On a daily basis, CASI closed higher 42% of trading days. The best single day was May 4, 1998 with a return of +329.6%, while the worst single day was Feb 25, 2026 at -74.1%.

CASI Pharmaceuticals, Inc. has an annualized alpha of 21.21%, beta of 0.89, and R² of 0.02 versus S&P 500 Index. Calculated based on daily prices since June 13, 1996.

• This stock participated in 173.87% of S&P 500 Index downside but only 28.65% of its upside — more exposed to losses than it benefited from rallies.
• R² of 0.02 means this stock moves largely independently of S&P 500 Index — capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.

CASI ranks 5 for risk / return — in the bottom 5% of stocks on our site. This means you're taking on significantly more risk than the returns justify. Consider whether the potential upside is worth the volatility, or explore alternatives with better risk / return profiles.

The table below present risk-adjusted performance metrics for CASI Pharmaceuticals, Inc. (CASI) and compare them to a chosen benchmark (S&P 500 Index).

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.

The table below displays the maximum drawdowns of the CASI Pharmaceuticals, Inc.. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the CASI Pharmaceuticals, Inc. was 100.00%, occurring on Feb 25, 2026. The portfolio has not yet recovered.

The current CASI Pharmaceuticals, Inc. drawdown is 100.00%.

The chart below shows the rolling one-month volatility.

The chart below illustrates the trends in the financial health of CASI Pharmaceuticals, Inc. over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.

The Valuation section provides an overview of how CASI Pharmaceuticals, Inc. is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.